Kathleen M. Zackowski, Ph.D., O.T.R.

Kathleen M. Zackowski, Ph.D., O.T.R.'s picture
Faculty Member, Kennedy Krieger Institute

Kennedy Krieger Institute
707 N. Broadway
Baltimore, MD 21205
Phone: (443) 923-2717
Email: zackowski@kennedykrieger.org

Kathleen M. Zackowski, PhD, OTR, is an associate professor at the Kennedy Krieger Institute and the Johns Hopkins University School of Medicine in the Departments of Physical Medicine & Rehabilitation, and Neurology.

Biographical Sketch: 

Dr. Zackowski earned her bachelor's of science in occupational therapy from Texas Tech University and went on to complete her master's of science in exercise and sport science from the University of Arizona. She worked as an occupational therapist in Texas, Arizona and California for several years before pursuing her doctorate. She completed her PhD in movement science through the program in physical therapy at Washington University in St. Louis. Dr. Zackowski completed her post-doctoral work at the Kennedy Krieger Institute/Johns Hopkins School of Medicine in the Department of Neurology. Dr. Zackowski is currently an Associate Professor in the Departments of Physical Medicine & Rehabilitation, and Neurology.

Research Summary: 

Dr. Zackowski studies the motor control problems that occur as a result of neurodegenerative disease processes such as multiple sclerosis and adrenomyeloneuropathy. Her research interests are to investigate the mechanisms that underlie sensorimotor impairments and disability resulting from damage to the central nervous system so as to improve disability. Dr. Zackowski has developed a model using advanced neuro-imaging, within the Kirby Imaging Center, in combination with quantitative impairment measures to understand pathologically relevant structure-function relationships in individuals with neurodegenerative disease. In this model she links impairment measures to performance measures (i.e., measures of walking and balance) to enable the development of pathologically specific rehabilitative interventions. This type of model may be very helpful in tracking disease progression and evaluating rehabilitative and pharmacologic treatments for people with neurodegenerative diseases. Dr. Zackowski’s studies extend broadly from clinical questions that can be addressed in the laboratory, and results applied in the clinic, to more theoretic questions that evaluate the mechanisms responsible for motor dysfunction.

Research Publications:

Zackowski KM (2016). Gait and Balance Assessment. Semin Neurol. 36(5), 474-478. Abstract
Oh J, Zackowski K, Chen M, Newsome S, Saidha S, Smith SA, Diener-West M, Prince J, Jones CK, Van Zijl PC, Calabresi PA, Reich DS (2013). Multiparametric MRI correlates of sensorimotor function in the spinal cord in multiple sclerosis. Mult Scler. 19(4), 427-35. Abstract
Davalos-Bichara M, Lin FR, Carey JP, Walston JD, Fairman JE, Schubert MC, Barron JS, Hughes J, Millar JL, Spar A, Weber KL, Ying HS, Zackowski KM, Zee DS, Agrawal Y (2013). Development and validation of a falls-grading scale. J Geriatr Phys Ther. 36(2), 63-7. Abstract
Keller JL, Wang JI, Kang JY, Hanson JA, Kamath P, Swain JO, Raymond GV, Zackowski KM (2012). Strength: a relevant link to functional performance in the neurodegenerative disease of adrenomyeloneuropathy. Neurorehabil Neural Repair. 26(9), 1080-8. Abstract
Shiee N, Bazin PL, Zackowski KM, Farrell SK, Harrison DM, Newsome SD, Ratchford JN, Caffo BS, Calabresi PA, Pham DL, Reich DS (2012). Revisiting brain atrophy and its relationship to disability in multiple sclerosis. PLoS One. 7(5), e37049. Abstract
Newsome SD, Wang JI, Kang JY, Calabresi PA, Zackowski KM (2011). Quantitative measures detect sensory and motor impairments in multiple sclerosis. J Neurol Sci. 305(1-2), 103-11. Abstract
Morton SM, Tseng YW, Zackowski KM, Daline JR, Bastian AJ (2010). Longitudinal tracking of gait and balance impairments in cerebellar disease. Mov Disord. 25(12), 1944-52. Abstract
Zackowski KM, Smith SA, Reich DS, Gordon-Lipkin E, Chodkowski BA, Sambandan DR, Shteyman M, Bastian AJ, van Zijl PC, Calabresi PA (2009). Sensorimotor dysfunction in multiple sclerosis and column-specific magnetization transfer-imaging abnormalities in the spinal cord. Brain. 132(Pt 5), 1200-9. Abstract
Reich DS, Zackowski KM, Gordon-Lipkin EM, Smith SA, Chodkowski BA, Cutter GR, Calabresi PA (2008). Corticospinal tract abnormalities are associated with weakness in multiple sclerosis. AJNR Am J Neuroradiol. 29(2), 333-9. Abstract
Reich DS, Smith SA, Zackowski KM, Gordon-Lipkin EM, Jones CK, Farrell JA, Mori S, van Zijl PC, Calabresi PA (2007). Multiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis. Neuroimage. 38(2), 271-9. Abstract
Reich DS, Smith SA, Jones CK, Zackowski KM, van Zijl PC, Calabresi PA, Mori S (2006). Quantitative characterization of the corticospinal tract at 3T. AJNR Am J Neuroradiol. 27(10), 2168-78. Abstract

Other Publications:

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