Amy J.
Bastian
,
PhD, PT

Amy J. Bastian, PhD, PT's picture
Chief Science Officer, Kennedy Krieger Institute Director, Motion Analysis Laboratory
Phone: 443-923-2716
Kennedy Krieger Institute

707 N. Broadway
Baltimore, MD 21205
United States

Research Departments

About

Dr. Amy Bastian is the chief science officer at Kennedy Krieger Institute, a role in which she identifies and promotes new directions for breakthrough research into the developing brain, spinal cord, and musculoskeletal system. She is also director of the Motion Analysis Laboratory that studies the neural control of human movement. Dr. Bastian is a professor of neuroscience and neurology at the Johns Hopkins University School of Medicine.

Education

After completing her undergraduate degree in physical therapy at the University of Oklahoma, Dr. Bastian completed her doctoral degree in movement science at Washington University in 1995, and a post-doctoral fellowship in neuroscience at Washington University under Dr. W.T. Thach. Dr. Bastian came to Kennedy Krieger Institute in Summer 2001. Prior to that, she was an assistant professor in physical therapy in the Department of Anatomy and Neurobiology at the Washington University School of Medicine in St. Louis.

Research

Dr. Bastian’s research uses computerized movement tracking techniques, non-invasive brain stimulation, novel devices and robotics to control walking and reaching movements. She studies how people with and without neurological damage control movement and learn new patterns. Some of her recent accomplishments include a series of papers on learning new walking patterns using a novel ‘split-belt’ treadmill published in the Journal of Neuroscience, Brain, and Nature Neuroscience. She has coauthored over 100 scientific papers and numerous book chapters and served as chair of the Musculoskeletal Rehabilitation Study Section at the National Institutes of Health (NIH). Dr. Bastian has given many named lectures, including a special lecture at the Society for Neuroscience meeting in 2014. She is currently the primary investigator on two R01 grants from the NIH, one of which recently received a prestigious Javits award from the National Institute of Neurological Disorders and Stroke (NINDS). Dr. Bastian has served on many national neuroscience and rehabilitation committees.

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Elsevier Fingerprint Engine Profile for Amy Bastian

Research Publications

Leech KA, Roemmich RT, Bastian AJ (2018). Creating flexible motor memories in human walking. Sci Rep. 8(1), 94.

Weeks HM, Therrien AS, Bastian AJ (2017). The cerebellum contributes to proprioception during motion. J Neurophysiol. , jn.00417.2016. Abstract

Roemmich RT, Long AW, Bastian AJ (2016). Seeing the Errors You Feel Enhances Locomotor Performance but Not Learning. Curr Biol. 26(20), 2707-2716. Abstract

Bar H, Mentch L (2016). R-CMap-An open-source software for concept mapping. Eval Program Plann. , . Abstract

Weeks HM, Therrien AS, Bastian AJ (2016). Proprioceptive Localization Deficits in People With Cerebellar Damage. Cerebellum. , .

Seitz J, Hueck M, Dahmen B, Schulte-Rüther M, Legenbauer T, Herpertz-Dahlmann B, Konrad K (2016). Attention Network Dysfunction in Bulimia Nervosa - An fMRI Study. PLoS One. 11(9), e0161329. 

Long AW, Finley JM, Bastian AJ (2015). A marching-walking hybrid induces step length adaptation and transfers to natural walking. J Neurophysiol. 113(10), 3905-14. 

Roemmich RT, Bastian AJ (2015). Two ways to save a newly learned motor pattern. J Neurophysiol. 113(10), 3519-30. 

Keller JL, Bastian AJ (2014). A home balance exercise program improves walking in people with cerebellar ataxia. Neurorehabil Neural Repair. 28(8), 770-8.

Bhanpuri NH, Okamura AM, Bastian AJ (2014). Predicting and correcting ataxia using a model of cerebellar function. Brain. 137(Pt 7), 1931-44.

Musselman KE, Stoyanov CT, Marasigan R, Jenkins ME, Konczak J, Morton SM, Bastian AJ(2014). Prevalence of ataxia in children: a systematic review. Neurology. 82(1), 80-9.

Gibo TL, Bastian AJ, Okamura AM (2013). Cerebellar ataxia impairs modulation of arm stiffness during postural maintenance. J Neurophysiol. 110(7), 1611-20.

Bhanpuri NH, Okamura AM, Bastian AJ (2013). Predictive modeling by the cerebellum improves proprioception. J Neurosci. 33(36), 14301-6.

Gibo TL, Criscimagna-Hemminger SE, Okamura AM, Bastian AJ (2013). Cerebellar motor learning: are environment dynamics more important than error size? J Neurophysiol. 110(2), 322-33.

Reisman DS, McLean H, Keller J, Danks KA, Bastian AJ (2013). Repeated split-belt treadmill training improves poststroke step length asymmetry. Neurorehabil Neural Repair. 27(5), 460-8.

Hoyer EH, Bastian AJ (2013). The effects of task demands on bimanual skill acquisition.Exp Brain Res. 226(2), 193-208.

Kurtzer I, Trautman P, Rasquinha RJ, Bhanpuri NH, Scott SH, Bastian AJ (2013). Cerebellar damage diminishes long-latency responses to multijoint perturbations. J Neurophysiol. 109(8), 2228-41. Abstract

Finley JM, Bastian AJ, Gottschall JS (2013). Learning to be economical: the energy cost of walking tracks motor adaptation. J Physiol. 591(4), 1081-95. Abstract

Charles SK, Okamura AM, Bastian AJ (2013). Does a basic deficit in force control underlie cerebellar ataxia? J Neurophysiol. 109(4), 1107-16.

Fuentes CT, Mostofsky SHBastian AJ (2011). No proprioceptive deficits in autism despite movement-related sensory and execution impairments. J Autism Dev Disord. 41(10), 1352-61.

Jayaram G, Galea JM, Bastian AJ, Celnik P (2011). Human locomotor adaptive learning is proportional to depression of cerebellar excitability. Cereb Cortex. 21(8), 1901-9.

Vasudevan EV, Torres-Oviedo G, Morton SM, Yang JF, Bastian AJ (2011). Younger is not always better: development of locomotor adaptation from childhood to adulthood. J Neurosci. 31(8), 3055-65.

Torres-Oviedo G, Bastian AJ (2010). Seeing is believing: effects of visual contextual cues on learning and transfer of locomotor adaptation. J Neurosci. 30(50), 17015-22.

Fuentes CT, Mostofsky SHBastian AJ (2010). Perceptual reasoning predicts handwriting impairments in adolescents with autism. Neurology. 75(20), 1825-9. 

Malone LA, Bastian AJ (2010). Thinking about walking: effects of conscious correction versus distraction on locomotor adaptation. J Neurophysiol. 103(4), 1954-62. 

Criscimagna-Hemminger SE, Bastian AJ, Shadmehr R (2010). Size of error affects cerebellar contributions to motor learning. J Neurophysiol. 103(4), 2275-84. 

Block HJ, Bastian AJ (2010). Sensory reweighting in targeted reaching: effects of conscious effort, error history, and target salience. J Neurophysiol. 103(1), 206-17. 

Fuentes CT, Bastian AJ (2010). Where is your arm? Variations in proprioception across space and tasks. J Neurophysiol. 103(1), 164-71.

Vasudevan EV, Bastian AJ (2010). Split-belt treadmill adaptation shows different functional networks for fast and slow human walking. J Neurophysiol. 103(1), 183-91. 

Fuentes CT, /patient-care/faculty-staff/amy-bastian" target="_blank">Bastian AJ (2009). Children with autism show specific handwriting impairments. Neurology. 73(19), 1532-7. 

Zackowski KMSmith SA, Reich DS, Gordon-Lipkin E, Chodkowski BA, Sambandan DR, Shteyman M, Bastian AJvan Zijl PC, Calabresi PA (2009). Sensorimotor dysfunction in multiple sclerosis and column-specific magnetization transfer-imaging abnormalities in the spinal cord. Brain. 132(Pt 5), 1200-9. 

/patient-care/faculty-staff/amy-bastian" target="_blank">Bastian AJ (2009). Walking flexibility after hemispherectomy: split-belt treadmill adaptation and feedback control. Brain. 132(Pt 3), 722-33. 

 

Bastian AJ (2008). Understanding sensorimotor adaptation and learning for rehabilitation.Curr Opin Neurol. 21(6), 628-33. 

Bo J, Block HJ, Clark JE, Bastian AJ (2008). A cerebellar deficit in sensorimotor prediction explains movement timing variability. J Neurophysiol. 100(5), 2825-32.

Gidley Larson JC, Bastian AJ, Donchin O, Shadmehr R, Mostofsky SH (2008). Acquisition of internal models of motor tasks in children with autism. Brain. 131(Pt 11), 2894-903.

Kluzik J, Diedrichsen J, Shadmehr R, Bastian AJ (2008). Reach adaptation: what determines whether we learn an internal model of the tool or adapt the model of our arm? J Neurophysiol. 100(3), 1455-64. 

Thakur PH, Bastian AJ, Hsiao SS (2008). Multidigit movement synergies of the human hand in an unconstrained haptic exploration task. J Neurosci. 28(6), 1271-81. 

Choi JT, Bastian AJ (2007). Adaptation reveals independent control networks for human walking. Nat Neurosci. 10(8), 1055-62. Abstract

Tseng YW, Diedrichsen J, Krakauer JW, Shadmehr R, Bastian AJ (2007). Sensory prediction errors drive cerebellum-dependent adaptation of reaching. J Neurophysiol. 98(1), 54-62.

Fuentes CT, Bastian AJ (2007). 'Motor cognition' - what is it and is the cerebellum involved? Cerebellum. 6(3), 232-6. 

Bastian AJ (2006). Learning to predict the future: the cerebellum adapts feedforward movement control. Curr Opin Neurobiol. 16(6), 645-9. 

Gordon LM, Keller JL, Stashinko EE, Hoon AH, Bastian AJ (2006). Can spasticity and dystonia be independently measured in cerebral palsy? Pediatr Neurol. 35(6), 375-81. 

Zackowski KM, Dubey P, Raymond GVMori SBastian AJMoser HW (2006). Sensorimotor function and axonal integrity in adrenomyeloneuropathy. Arch Neurol. 63(1), 74-80.