Longitudinal ADHD Research Study for Adolescents Ages 12-17 years old
This study is currently recruiting
Study Name: Adolescent Changes in Brain and Behavior in Boys and Girls with ADHD
Description: This research study is being done to learn more about response control and anatomical brain differences in adolescents, between the ages of 12 and 17 years old, with and without ADHD. This research study will help to evaluate brain development and functional outcomes over the course of childhood and adolescence. The study takes place over two days, from about 8:45am – 3:45pm, with an hour break for lunch. The testing is completed at the Kennedy Krieger Institute in Baltimore City, 716 North Broadway, 3rd Floor. During the first visit, participants will receive an IQ test, participate in a semi-structured interview, and complete computer games. During the second visit, participants will complete motor testing, a 60-minute MRI scan, and a 90-minute electroencephalogram (EEG). Parents will complete a 1-2-hour semi-structured interview. No radiation or dyes are used, only magnets. For their participation, children will receive a check for $50.00 per day of study participation; they will also receive a picture of their brain if they are able to complete the MRI scan. Parents will receive an evaluation report on the IQ and achievement test results of their child. There is no charge to participate in the study.
Eligibility & Criteria
IRB #: IRB00064633
Principal Investigator: Stewart Mostofsky
Eligible Age Range: 12 - 17 years
Gender: All
Diagnosis: Are typically developing OR have ADHD. Children with a history of Autism Spectrum Disorders (ASD), traumatic brain injury, and/or developmental delays may not be eligible to participate.
Contact Information: Alyssa DeRonda, deronda@kennedykrieger.org, 443-923-9258
Study Keywords: ADHD
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Understanding Motor Movement in Children With and Without ADHD
This study is currently recruiting
Study Name: Anomalous Motor System Physiology in ADHD: Biomarker Validation and Modeling Domains of Function
Description: Diagnosing Attention Deficit Hyperactivity Disorder (ADHD) largely relies on subjective rating scales that neglect physiological differences between children with and without ADHD. The goal of this study is to identify and validate brain-based physiological biomarkers that can be used like measurements of ADHD and help improve treatment.
This study requires 2 or 3 full day visits, from about 8:45am-3:45pm, to the Kennedy Krieger Institute, 716 North Broadway, Baltimore, MD. During the research visit, participants will complete an IQ assessment, motor assessments, computer games, and two 2-hour transcranial magnetic stimulation (TMS) sessions. Participants with ADHD will also receive either a placebo or methylphenidate before one of the TMS sessions.
Participants will receive a check 4-6 weeks after their last research visit in the amount of $50 per day. Parents will receive an evaluation summary of their child's performance on the IQ assessment. This is no cost for participating in the study.
Eligibility & Criteria
IRB #: IRB00251063
Principal Investigator: Stewart Mostofsky
Eligible Age Range: 8 - 12 years
Gender: All
Diagnosis: Children between the ages of 8-12 years old are eligible to participate. Children with and without an ADHD diagnoses are eligible. Children with a history of Autism Spectrum Disorders (ASD), traumatic brain injury, and/or developmental delays may not be eligible to participate.
Contact Information: Alyssa DeRonda, deronda@kennedykrieger.org, 443-923-9258
Study Keywords: ADHD, typically developing