This study is currently recruiting

Study Name: Anomalous Motor System Physiology in ADHD: Biomarker Validation and Modeling Domains of Function

Description: Diagnosing Attention Deficit Hyperactivity Disorder (ADHD) largely relies on subjective rating scales that neglect physiological differences between children with and without ADHD. The goal of this study is to identify and validate brain-based physiological biomarkers that can be used like measurements of ADHD and help improve treatment.

This study requires 2 or 3 full day visits, from about 8:45am-3:45pm, to the Kennedy Krieger Institute, 716 North Broadway, Baltimore, MD. During the research visit, participants will complete an IQ assessment, motor assessments, computer games, and two 2-hour transcranial magnetic stimulation (TMS) sessions. Participants with ADHD will also receive either a placebo or methylphenidate before one of the TMS sessions.

Participants will receive a check 4-6 weeks after their last research visit in the amount of $50 per day. Parents will receive an evaluation summary of their child's performance on the IQ assessment. This is no cost for participating in the study.

Eligibility & Criteria

IRB #: IRB00251063

Principal Investigator: Stewart Mostofsky

Eligible Age Range:  8 - 12 years

Gender: All

Diagnosis:  Children between the ages of 8-12 years old are eligible to participate. Children with and without an ADHD diagnoses are eligible. Children with a history of Autism Spectrum Disorders (ASD), traumatic brain injury, and/or developmental delays may not be eligible to participate.

Contact Information:  Alyssa DeRonda,, 443-923-9258

Study Keywords:  ADHD, typically developing