The Center for Genetic Disorders of Cognition and Behavior (GCB) focuses on advancing research and clinical practice for genetic disorders associated with severe cognitive and behavioral impairment in order to improve the quality of life for patients and their families. Major disorders investigated by the GCB Center include Fragile X Syndrome, Rett Syndrome, Down Syndrome, X-Linked Intellectual Disabilities and Smith-Lemli-Opitz-Syndrome.

The Center's staff includes clinicians and scientists trained in basic and clinical neurosciences who collaborate in multidisciplinary activities and research projects. The Center's goal is to generate and integrate knowledge from bench to patient across disorders and disciplines, as well as to provide information and guidance for affected individuals and their families.