Before completing a postdoctoral fellowship under the auspices of Dr. Richard Edden at Johns Hopkins, Dr. Oeltzschner received his undergraduate degree in Physics (2010) and graduate degree in Natural Sciences (2015) from Heinrich Heine University in Düsseldorf, Germany. From 2016 to 2020, he completed a postdoctoral fellowship in Neuroradiology at Johns Hopkins University under the supervision of Prof. Richard Edden. In 2020, he assumed a faculty position as an Instructor in the Department of Radiology and Radiological Science at Johns Hopkins. Dr. Oeltzschner’s research interests concern the development of advanced magnetic resonance spectroscopy (MRS) acquisition techniques for low-concentration brain metabolites, novel data processing and quantification methods, and new clinical applications of these techniques.
Dr. Oeltzschner's research is dedicated to developing modern techniques to measure levels of important biochemicals in the living human brain using magnetic resonance spectroscopy. He is particularly focused on improving the detection of neurotransmitters (GABA, glutamate, aspartate), antioxidants (glutathione, ascorbate), and potential molecular markers of brain tumor mutations (2-hydroxyglutarate, cystathionine). The techniques he develops are used to investigate the neurochemical confounds in a wide range of neurological and psychiatric disorders. Currently, he studies the levels of brain metabolites in patients with mild cognitive impairment. Further research projects he is involved in concern various neurodevelopmental disorders (autism spectrum disorder, attention-deficit/hyperactivity disorder, Tourette’s syndrome), tuberous sclerosis, hepatic encephalopathy, and glioma. A recent major focus of his attention is the standardization of data acquisition and analysis. He believes that the magnetic resonance community can reap great benefit from embracing the practices of the Open Science movement: adapting code sharing, standardizing data acquisition, and streamlining pipelines for processing, quantifying, and interpreting spectroscopic data.
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