Dr. Ann Choe has completed her undergraduate (2004) and Ph.D. (2010) degrees in Biomedical Engineering from the Vanderbilt University. She joined the International Center for Spinal Cord Injury (ICSCI) and the F.M. Kirby Center at Kennedy Krieger Institute as a postdoctoral fellow under the supervision of Drs. John W. McDonald and Peter van Zijl, respectively. Dr. Choe is currently an Assistant Professor in the Department of Radiology at the Johns Hopkins School of Medicine.
Early detection of response to therapeutic intervention is vital, as it will enable early termination of intervention in non-responding patients, prevent unnecessary financial burden, and allow for early changes of programs. Studies have shown that functional MRI (fMRI) can detect early brain functional network changes in patients with spinal cord injury (SCI) and that patterns of the functional reorganization may be predictive of recovery. Resting-state functional MRI (rs-fMRI) is an advanced MR imaging modality that allows non-invasive monitoring of cortical functional network changes. Additionally, rs-fMRI does not require the performance of sensorimotor tasks, which makes the method especially suitable for the SCI patient population. My primary research interest is to establish brain functional connectivity as an advanced neuroimaging biomarker of recovery in individuals with SCI. My ongoing studies' goals are: 1) to assess the effect of rehabilitative intervention – specifically, functional electric stimulation (FES) – in SCI patients using functional connectivity, and 2) to evaluate the reproducibility and reliability of various rs-fMRI derived outcome measures.
Kirby Center, Kennedy Krieger Institute
707 N. Broadway
Baltimore, Maryland, 21205
Click the link below for a list of Dr. Choe's publications: