Publications from the Brain Dynamics Lab

Geffrey AL, Kwon H, Shi W, Daly N, Philbin A, Sisterson ND, Williams ZM, Kahle KT, Richardson RM, Chu CJ. Seizure and quality-of-life outcomes following responsive neurostimulation treatment for drug-resistant epilepsy in children and young adults. Journal of Neurosurgery: Pediatrics. 2026;1–13. https://doi.org/10.3171/2025.9.PEDS25200.

McLaren JR, Muñoz W, Kwon H, Geffrey AL, Nanda P, Thibert R, Grossmann L, Stufflebeam S, Jaimes C, Emerton BC, Kahle KT, Richardson RM, Chu CJ. Expanding the scope of pediatric epilepsy surgery: Access, indications, and outcomes in a modern cohort. Epilepsia Open. 2026; https://doi.org/10.1002/epi4.70257.

Glass HC, Numis AL, Soul JS, Wusthoff CJ, Lemmon ME, Benedetti GM, Chu CJ, Massey SL, Thomas C, Anwar T, Sturza J, Berl MM, Li Y, Rogers EE, Rau S, Gidley Larson JC, Guerrero JL, Frank LS, McCulloch CE, Shellhaas RA. Ann Neurol. 2026 (in press). PMID: 41482857. https://doi.org/10.1002/ana.78100

Shaw DC Kondabolu K, Walsh KG, Abumuaileq M, Shi W, Isaac K, Steiner L, Rillosi E, Hsiung M, Dang L, Eden UT, Richardson RM, Kramer MA, Chu CJ^* Xan H^*. ^*co-senior authors. Photothrombosis-induced cortical stroke mouse model produces electrographic epileptic human biomarkers. Exp Neurol. 2026;396:115542. https://doi.org/10.1016/j.expneurol.2025.115542

Christison-Lagay KL, Khalaf A, Freedman NC, Micek C, Kronemer SI, Gusso MM, Kim L, Forman S, Ding J, Aksen M, Abdel-Aty A, Kwon H, Markowitz N, Yeagle E, Espinal E, Herrero J, Bickel S, Young J, Mehta A, Wu K, Gerrard J, Damisah E, Spencer D, Blumenfeld H. The neural activity of auditory conscious perception. Neuroimage. 2025;308:121041. https://doi.org/10.1016/j.neuroimage.2025.121041

Kwon H, Chinappen DM, Kinard EA, Goodman SK, Huang JF, Berja ED, Walsh KG, Shi W, Manoach DM, Kramer MA, Chu CJ. Association of sleep spindle rate with memory consolidation in children with Rolandic epilepsy. Neurology. 2025; 104(2):e210232. https://doi.org/10.1212/WNL.0000000000210232

Peng GS, Halsey K, Wusthoff CJ, Chu CJ, Massey SL, Lemmon ME, Thomas C, Numis AL, Benedetti GM, Sturza J, Rogers EE, Franck LS, McCulloch CE, Soul JS, Shellhaas RA, Bonifacio SL, Glass HC. Preferred parental language and neurodevelopmental outcomes among infants with acute provoked neonatal seizures in the United States. Ped Neurol. 2025;164;115-121. https://doi.org/10.1016/j.pediatrneurol.2024.12.010

Sjøgård M*, Baxter B*, Mylonas D, Thompson M, Kwok K, Driscoll B, Tolosa A, Shi W, Stickgold R, Vangel M, Chu CJ+, Manoach DM+. +co-last authors. Hippocampal ripples predict motor learning during brief rest breaks in humans. Nat Comm. 2025;16(1):6089. https://doi.org/10.1038/s41467-025-61136-y

Barbour K, Hussain S, Knupp K, Berg AT, Chu CJ, Coryell J, Sanchez-Fernandez I, Gaillard W, Harini C, Keator C, Loddenkemper T, Mitchell W, Mytinger J, Nordli D, Patel A, Shellhaas RA, Singhal N, Ingacio V, Wirrell E, Wusthoff CJ, Yozawt E, Grinspan ZA. Comparative effectiveness of second line treatments for epileptic spasms. Epilepsia. 2025 (in press). https://doi.org/10.1111/epi.18511

Sun C, Jing J, Turley N, Alcott C, Kang W, Cole AJ, Goldenholz D, Lam A, Amorim E, Chu CJ, Cas S, Moura V, Gupta A, Ghanta M, Nearing B, NascimentoFA, Struck A, Kim J, Sartipi S, Tauton A, Fernandes M, Sun H, Bayas G, Gallagher K, Wagenaar JB, Sinha N, Lee-Messer C, Silvers C, Gunapati B, Rosand J, Peters J, LoddenkemperT, Lee, JW, Zafar S, Westover MB. Harvard electroencephalography database: a comprehensive clinical electroencephalographic resources from four Boston hospitals. Epilepsia. 2025 (in press). https://doi.org/10.1111/epi.18487

Numis AL, Glass HC, Soul JS, Wusthoff CJ, Massey SL, Benedetti GM, Chu CJ, Thomas C, Anwar T, Lemmon ME, Franck LS, Berl MM, Pilon B, Rau SMD, Sturza J, McCulloch CE, Shellhaas RA. Post-neonatal epilepsy after acute provoked neonatal seizures: incidence, predictors, and clinical burden in a multicenter cohort followed through early childhood. Epilepsia. 2025 (in press). https://doi.org/10.1111/epi.18590

Shappell HM, Kramer MA, Chu CJ, Kolaczyk ED. Accounting for edge uncertainty in stochastic actor-oriented models for dynamic network analysis. Network Science. 2025 (in press). https://doi.org/10.1017/nws.2025.6

Frank LS, Lemmon ME, Grossbauer L, Pawlowski K, Sturza JS, Wusthoff CJ, Massey SL, Chu CJ, Soul JS, Numis AL, Thomas C, Benedett GM, Anwar T, Berl MM, Gidley Larson JC, Rogers EE, Chen C, McCulloch CE, Glass HC, Shellhaas RA. Parent and family well-being and associated risk factors as children with neonatal seizures reach preschool and school-age: a longitudinal cohort study. J Peds: Clin Prac. 2025 (in press). https://doi.org/10.1016/j.jpedcp.2025.200149

Kwon H, Chinappen DM, Wodeyar A, Kinard EA, Goodman SK, Shi W, Baxter BS, Manoach DS, Kramer MA, Chu CJ. Clin Neurophysiol. 2025; 183: 2111475. https://doi.org/10.1016/j.clinph.2025.2111475

Carbonero D, Noueihed J, Kramer MA, White JA. Nonnegative matrix factorization for analyzing state dependent neuronal network dynamics in calcium recordings. Scientific Reports. 2024;14(1):27899. https://doi.org/10.1038/s41598-024-78448-6

Mclaren JR, Kahle KT, Richardson RM, Chu CJ. Epilepsy surgery for cognitive improvement in epileptic encephalopathy. Neurosurg Clin N Am. 2024; 35(1): 49-59. https://doi.org/10.1016/j.nec.2023.08.002

Rifkin RA, Wu X, Pereira B, Gill BJA, Merricks EM, Michalak AJ, Goldberg AR, Humala N, Dovas A, Rai G, McKhann GM, Slesinger PA, Canoll P, Schevon CA. A selective small-molecule agonist of G protein-gated inwardly-rectifying potassium channels reduces epileptiform activity in mouse models of tumor-associated and provoked seizures. Neuropharmacology. 2025; 265:110259. https://doi.org/10.1016/j.neuropharm.2024.110259

Zarr VM, Liou JY, Merricks EM, Davis TS, Thomson K, Greger B, House PA, Emerson RG, Goodman RR, McKhann GM, Sheth SA, Schevon CA, Rolston JD, Smith EH. Protocol for detecting and analyzing non-oscillatory traveling waves from highspatiotemporal-resolution human electrophysiological recordings. STAR protocols. 2025; 6(1):103659. https://doi.org/10.1016/j.xpro.2025.103659

Goldberg AR, Dovas A, Torres D, Pereira B, Viswanathan A, Das Sharma S, Mela A, Merricks EM, Megino-Luque C, McInvale JJ, Olabarria M, Abrishami Shokooh L, Zhao HT, Chen C, Kotodis C, Calvaresi P, Banu MA, Razavilar A, Sudhaker TD, Saxena A, Chokran C, Humala N, Mahajan A, Xu W, Metz JB, Bushong EA, Boassa D, Ellisman MH, Hillman EMC, Hargus G, Bravo-Cordero JJ, McKhann GM, Gill BJA, Rosenfeld SS, Schevon CA, Bruce JN, Sims PA, Peterka DS, Canoll P. Gliomainduced alterations in excitatory neurons are reversed by mTOR inhibition. Neuron. 2025;113(6):858–875.E10. https://doi.org/10.1016/j.neuron.2024.12.026

Cowan RL, Davis TS, Merricks EM, Kundu B, Shofty B, Rahimpour S, Schevon CA, Rolston JD, Smith EH. Cell-type-specific responses to single-pulse electrical stimulation of the human brain. Brain Stimulation. 2025;18(4):1266–1278. https://doi.org/10.1016/j.brs.2025.06.017

Wusthoff CJ, Numis AL, Pressler RM, Chu CJ, Massey S, Clancy RR, Nguyen S, Hahn CD, Scher MS, Pilon B, King III DT. The American clinical neurophysiology society guideline on indications for continuous electroencephalography monitoring in neonates. Journal of Clinical Neurophysiology. 2025;42(1):1-1. https://doi.org/10.1097/WNP.0000000000001120

Shi W, Shaw D, Walsh KG, Han X, Eden UT, Richardson RM, Gliske SV, Jacobs J, Brinkmann BH, Worrell GA, Stacey WC, Kramer MA, Chu CJ. Spike ripples localize the epileptogenic zone better than other leading biomarkers: a multicenter intracranial study. Brain. 2024;147(7):2496-2506. https://doi.org/10.1101/2023.04.25.23289111
     Highlighted in the Editorial: Quraishi IH. Spike ripples: hidden clues to the mystery of the epileptogenic zone. Epilepsy Currents. 2025; 0(0). 

Wodeyar A, Chinappen D, Mylonas D, Baxter B, Manoach D, Eden UT, Kramer MA, Chu CJ. Thalamic epileptic spikes disrupt sleep spindles in patients with epileptic encephalopathy. Brain. 2024; 147(8):2803-2816. https://doi.org/10.1093/brain/awae119

Berja ED, Kwon H, Walsh KG, Bates SV, Kramer MA, Chu CJ. Infant sleep spindle measures from EEG improve prediction of cerebral palsy. Clinical Neurophysiology. 2024;167:51-60. https://doi.org/10.1016/j.clinph.2024.08.017

Field NK, Franck LS, Shellhaas RA, Glass HC, Young KA, Dhar S, Hamlett A, Pilon B, Means K, Soul JS, Massey SL, Wusthoff CJ, Chu CJ, Thomas C, Rogers E, Berl MM, Benedetti GM, Anwar T, Lemmon ME. Life After Neonatal Seizures: Characterizing the Longitudinal Parent Experience. Pediatr Neurol.  2024;161:76-83.  https://doi.org/10.1016/j.pediatrneurol.2024.08.007

Schlafly ED, Carbonero D, Chu CJ, Kramer MA. A data augmentation procedure to improve detection of spike ripples in brain voltage recordings. Neurosci Res. 2024. [Epub ahead of print]. https://doi.org/10.1016/j.neures.2024.07.005

Nanda P, Sisterson N, Walton A, Chu CJ, Cash SS, Moura L, Oster J, Urban A, Richardson RM. Centromedian-region thalamic responsive neurostimulation mitigates primary and rapidly generalized multifocal epilepsies: a case series. Epilepsia. 2024 (in press). https://doi.org/10.1111/epi.18070

Kramer MA, Chu CJ.  A General, Noise-Driven Mechanism for the 1/f-Like Behavior of Neural Field Spectra.  Neural Comput. 2024;36(8):1643-1668. https://doi.org/10.1162/neco_a_01682

Mattes AM, Shellhaas RA, Glass HC, Sturza J, Rau S, Lemmon M, Rogers EE, Numis A, Soul JS, Berl M, Wusthoff CJ, Chu CJ, Massey SL, Thomas C, Franck LS, McCulloch CE, Benedetti GM, Means J, Anwar T, Gidley Larson JC. Neonatal seizures and associated neurobehavioral profiles in preschool age children. Pediatr Neurol. 2024;163:76-81. https://doi.org/10.1016/j.pediatrneurol.2024.11.008

Shellhaas RA, Franck LS, Pilon B, Wusthoff CJ, Massey SL, Chu CJ, Soul JS, Lemmon ME, Numis AL, Sturza JS, Thomas C, Benedetti GM, Rau SMD, Anwar T, Berl MM, McCulloch Ce, Glass HC. Sleep disorders five years after acute provoked neonatal seizures. J Pediatr. 2024;278:114412. https://doi.org/10.1016/j.jpeds.2024.114412

Juan E, Górska U, Kozma C, Papantonatos C, Bugnon T, Denis C, Kremen V, Worrell G, Struck AF, Bateman LM, Merricks EM, Blumenfeld H, Tononi G, Schevon CA, Boly M. Distinct signatures of loss of consciousness during focal impaired awareness versus focal to bilateral tonic clonic seizures. Brain. 2023; 146(1):109–123. https://doi.org/10.1101/2021.10.01.462586

Lee S, Deshpande SS, Merricks EM, van Putten MJAM, Schevon CA, van Drongelen W. Spatiotemporal spike-centered averaging reveals symmetry of temporal and spatial components of the spike-LFP relationship during human focal seizures. Communications Biology. 2023;6(1):317. https://doi.org/10.1038/s42003-023-04696-3

Agopyan-Miu AH¹,Merricks EM¹, Smith EH, McKhann GM, Sheth SA, Feldstein, NA, Trevelyan AJ, Schevon CA. Cell-type specific and multiscale dynamics of human focal seizures in limbic structures. Brain. 2023;146(12):5209–5223. Co-first author¹. https://doi.org/10.1093/brain/awad262

Shellhaas RA, Lemmon ME, Gosselin BN, Sturza J, Frank LS, Glass HC, for the Neonatal Seizure Registry. Toward equity in research participation: association of financial impact with in-person study participation. Ped Neurol. 2023; 144:107-109. https://doi.org/10.1016/j.pediatrneurol.2023.04.019

Chinappen DM, Xiao G, Jing J, Spencer ER, Eden UT, Kramer MA, Westover MB, Chu CJ. Spike height improves prediction of future seizure risk. Clin Neurophysiol 2023; 150:49-55. https://doi.org/10.1016/j.clinph.2023.02.180

Khalaf A, Kronemer SI, Christison-Lagay K, Kwon H, Li J, Wu K, Blumenfeld H. Early neural activity changes associated with stimulus detection during visual conscious perception. Cereb Cortex. 2023; 33(4):1347–1360. https://doi.org/10.1093/cercor/bhac140

Kwon H, Walsh KG, Berja ED, Manoach DS, Eden UT, Kramer MA, Chu CJ. Sleep spindles in the healthy brain from birth through 18 years. Sleep. 2023 [Epub ahead of print]. https://doi.org/10.1093/sleep/zsad017

Sun H, Ye E, Paixao L, Gangleberger W, Chu CJ, Zhang C, Rosand J, Mignot E, Cash SS, Gozal D, Thomas RJ, Westover MB. The sleep and wake electroencephalogram over the lifespan. Neurobiology of Aging. 2023;124:60-70. https://doi.org/10.1016/j.neurobiolaging.2023.01.006

Ostrowski LM, Chinappen DM, Stoyell SM, Song DY, Ross EE, Kramer MA, Emerton BC, Chu CJ. Children with Rolandic epilepsy have micro- and macrostructural abnormalities in white matter constituting networks necessary for language function. Epilepsy and Behavior. 2023;144:109254. https://doi.org/10.1016/j.yebeh.2023.109254

McLaren JR*, Luo Y*, Kwon H*, Shi W, Kramer MA, Chu CJ. Preliminary evidence of a relationship between sleep spindles and treatment response in epileptic encephalopathy. Annals Clin Transl Neurol 2023;10(9):1513-1524. https://doi.org/10.1002/acn3.51840

Roberts KH, Barks JDE, Glass HC, Soul JS, Chant T, Wusthoff CJ, Chu CJ, Massey SL, Abend NS, Lemmon ME, Thomas C, Guillet R, Rogers EE, Franck LS, McCaffery H, Li Y, McCulloch CE, Shellhaas RA. Feeding and developmental outcomes after neonatal seizures-A prospective observational study. Ann Child Neurol Soc .2023;1(3):209217. https://doi.org/10.1002/cns3.6

Mount RA, Athif M, O’Connor M, Saligrama A, Tseng HA, Sridhar S, Zhou C, Bortz E, San Antonio E, Kramer MA, Man HY. The autism spectrum disorder risk gene NEXMIF over-synchronizes hippocampal CA1 network and alters neuronal coding. Frontiers in Neuroscience. 2023;17:1277501. https://doi.org/10.3389/fnins.2023.1277501

Chinappen DM, Ostrowski LM, Spencer ER, Kwon H, Kramer MA, Hamalainen MS, Chu CJ. Decreased thalamocortical connectivity in resolved Rolandic epilepsy. Clin Neurophysiol. 2023;153:21-27. https://doi.org/10.1016/j.clinph.2023.05.013

Zhu X, Shappell H, Kramer MA, Chu CJ, Kolaczyk ED. Distinguishing between different percolation regimes in noisy dynamic networks with an application to epileptic seizures. PloS Comput Biol. 2023; 19:e1011188. https://doi.org/10.1371/journal.pcbi.1011188

Wodeyar A, Marshall FA, Chu CJ, Eden UT, Kramer MA. Different methods to estimate the phase of neural rhythms agree but only during time of low uncertainty. ENeuro. 2023;10(11):eneuro.0507-22.2023. https://doi.org/10.1523/ENEURO.0507-22.2023

Li Y, Scheffler A, Barkovich AJ, Chang T, Chu CJ, Massey SL, Abend NS, Lemmon ME, Thomas C, Numis A, Franck LS, Rogers E, Callen A, McCulloch CE, Shellhaas RA, Glass HC. Neonatal brain MRI and short-term outcomes after acute provoked seizures. J Perinatology. 2023;43:1392-1397. https://doi.org/10.1038/s41372-023-01723-3

Norman-Haignere SV, Long LK, Devinsky O, Doyle W, Irobunda I, Merricks EM, Feldstein NA, McKhann GM, Schevon CA, Flinker A, Mesgarani N. Multiscale temporal integration organizes hierarchical computation in human auditory cortex. Nature Human Behaviour. 2022; 6 (3):455-469. https://doi.org/10.1038/s41562-021-01261-y

Zemel D, Gritton H, Cheung C, Shankar S, Kramer M, Han X. Dopamine depletion selectively disrupts interactions between striatal neuron subtypes and LFP oscillations. Cell reports. 2022;38(3). https://doi.org/10.1016/j.celrep.2021.110265

Salami P, Borzello M, Kramer MA, Westover MB, Cash SS. Quantifying seizure termination patterns reveals limited pathways to seizure end. Neurobiology of disease. 2022;165:105645. https://doi.org/10.1016/j.nbd.2022.105645

Salami P, Borzello M, Kramer MA, Westover MB, Cash SS. Quantifying seizure termination patterns reveals limited pathways to seizure end. Neurobiology of disease. 2022165:105645. https://doi.org/10.1016/j.nbd.2022.105645

Smith EH, Liou JY, Merricks EM, Davis TS, Thomson K, Greger B, House PA, Emerson RG, Goodman RR, McKhann II GM, Sheth SA, Schevon CA, Rolston JD. Human interictal epileptiform discharges are bidirectional traveling waves echoing ictal discharges. ELife. 2022;11:e73541. https://doi.org/10.7554/eLife.73541

Schlafly E, Marshall F, Merricks EM, Eden UT, Cash SS, Schevon CA, Kramer MA. Multiple sources of fast traveling waves during human seizures: resolving a controversy. Journal of Neuroscience. 2022;42(36):6966-6982. https://doi.org/10.1523/JNEUROSCI.0338-22.2022

Gill BJA1, Khan,FA1, Goldberg AR1, Merricks EM1, Wu X, Sosunov AA, Sudhaker TD, Dovas A, Lado W, Michalak AJ, Liou J-Y, Frankel WN, McKhann GM, Canoll P, Schevon CA. Single unit analysis and wide-field imaging reveal alterations in excitatory and inhibitory neurons in glioma. Brain. 2022; 145(10), 3666–3680. Co-first author1. https://doi.org/10.1093/brain/awac168

Massey SL, Glass HC, Shellhaas RA, Bonifacio S, Chang T, Chu C, Cilio MR, Lemmon ME, McCulloch CE, Soul JS, Thomas C, Wusthoff CJ, Xiao R, Abend NS. Characteristics of Neonates with Cardiopulmonary Disease Who Experience Seizures: A Multicenter Study. J Pediatr. 2022;242:63-73. https://doi.org/10.1016/j.jpeds.2021.10.058

Baumer FM, Mytinger JR, Neville K, Briscoe Abath C, Gutierrez CA, Numis AL, Harini C, He Z, Hussain SA, Berg AT, Chu CJ, Gaillard WD, Loddenkemper T, Pasupuleti A, Samanta D, Singh RK, Singhal NS, Wusthoff CJ, Wirrell EC, Yozawitz E, Knupp KG, Shellhaas RA, Grinspan ZM; Pediatric Epilepsy Research Consortium; National Infantile Spasms Consortium. Inequities in Therapy for Infantile Spasms: A Call to Action. Ann Neurol. 2022;92(1):32-44. https://doi.org/10.1002/ana.26363

Peyton C, Girvan O, Shellhaas RA, Lemmon ME, Rogers EE, Soul JS, Chang T, Hamlett A, Wusthoff CJ, Chu CJ, Massey SL, Thomas C, Guillet R, Franck LS, Glass HC; Neonatal Seizure Registry. Impact of COVID-19 Pandemic on Developmental Service Delivery in Children With a History of Neonatal Seizures. Pediatr Neurol. 2022;129:14-18. https://doi.org/10.1016/j.pediatrneurol.2022.01.004

Spencer ES*, Shi W*, Komoroski R, Gilber J, Ostrowski L, Bird L, Thibert R, Bao C, Molloy F, Calhoun M, Koirala S, Jafar-Najad P, Rigo F, Kramer M, Chu CJ. Longitudinal EEG model detects antisense oligonucleotide treatment effect and increased UBE3A in Angelman syndrome. Brain Communications 2022; PMID: 35611307, PMCID: PMC9123847. https://doi.org/10.1093/braincomms/fcac106

Spencer ER, Chinappen D, Emerton BC, Morgan AK, Hamalainen MS, Manoach DS, Eden UT, Kramer MA, Chu CJ. Source EEG reveals that Rolandic epilepsy is a regional encephalopathy. Neuroimage Clinical. 2022;33:102956. https://doi.org/10.1016/j.nicl.2022.102956

Shi W, Zemel D, Sridhar S, Mount RA, Richardson RM, Eden UT, Han X, Kramer MA, Chu CJ. Spike ripples in striatum correlate with seizure risk in two mouse models. Epilepsy and Behavior Reports. 2022;18:100529. https://doi.org/10.1016/j.ebr.2022.100529

Kramer MA. Golden rhythms as a theoretical framework for cross-frequency organization. Neurons, behavior, data analysis and theory. 2022;1:10-51628. https://doi.org/10.51628/001c.38960

Kronemer SI, Aksen M, Ding JZ, Ryu JH, Xin Q, Ding Z, Prince JS, Kwon H, Khalaf A, Forman S, Jin DS, Wang K, Chen K, Hu C, Agarwal A, Saberski E, Wafa SMA, Morgan OP, Wu J, Christison-Lagay KL, Hasulak N, Morrell M, Urban A, Constable RT, Pitts M, Richardson RM, Crowley MJ, Blumenfeld H. Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity. Nat Commun. 2022;13:7342. https://doi.org/10.1038/s41467-022-35117-4

Mehta N, Shellhaas RA, McCulloch CE, Chang T, Wusthoff CJ, Abend NS, Lemmon ME, Chu CJ, Massey SL, Franck LS, Thomas C, Soul JS, Rogers E, Numis A, Glass HC. Seizure Burden, EEG, and Outcome in Neonates With Acute Intracranial Infections: A Prospective Multicenter Cohort Study.  Pediatr Neurol. 2022;137:54-61. https://doi.org/10.1016/j.pediatrneurol.2022.09.001

Kwon H, Chinappen DM, Huang JF, Berja ED, Walsh KG, Wen S, Kramer MA, Chu CJ. Transient, developmental functional and structural connectivity abnormalities in the thalamocortical motor network in Rolandic epilepsy. Neuroimage Clin. 2022;35:103102. https://doi.org/10.1016/j.nicl.2022.103102

Frohlich J, Chiang JN, Mediano PAM, Mespeca M, Saravanapandian V, Toker D, Dell-Italia J, Hipp JF, Jeste SS, Chu CJ, Bird LM, Monti MM. Neural complexity is a common denominator of human consciousness across diverse regimes of cortical dynamics. Commun Biol. 2022;5(1):1374. https://doi.org/10.1038/s42003-022-04331-7

Mehta N, Shellhaas RA, McCulloch CE, Change T, Wusthoff CJ, Abend NS, Lemmon ME, Chu CJ, Massey SL, Franck LS, Thomas C, Soul JS, Rogers E, Numis A, Glass HC. Seizure burden, EEG and outcome in neonates with acute intracranial infections: a prospective multicenter cohort. Pediatr Neurol. 2022;137:54-61. https://doi.org/10.1016/j.pediatrneurol.2022.09.001

Merricks, E.M., Smith, E.H., Emerson, R.G., Bateman, L.M., McKhann, G.M., Goodman, R.R., Sheth, S.A., Greger, B., House, P.A., Trevelyan, A.J., Schevon, C.A. Neuronal firing and waveform alterations through ictal recruitment in humans. Journal of Neuroscience. 2021; 41(4): 766-779. https://doi.org/10.1523/JNEUROSCI.0417-20.2020

Kramer MA, Stoyell SM, Chinappen D, Ostrowski LM, Spencer ER, Morgan AK, Emerton BC, Jing J, Westover MB, Eden UT, Stickgold R, Manoach DS, Chu CJ. Focal sleep spindle deficits reveal focal thalamocortical dysfunction and predict cognitive deficits in sleep activated developmental epilepsy. J Neuroscience. 2021;41(8):1816-29. https://doi.org/10.1523/JNEUROSCI.2009-20.2020

Crocker B, Ostrowski L, Williams ZM, Doughterty DD, Eskandar E, Widge AS, Chu CJ, Cash SS, Paulk AC. Local and distant responses to single pulse electrical stimulation reflect different forms of connectivity. Neuroimage. 2021;237:118094. https://doi.org/10.1016/j.neuroimage.2021.118094

Ostrowski LM, Spencer ER, Bird LM, Thibert R, Komorowski RW, Kramer MA, Chu CJ. Delta power robustly predicts cognitive function in Angelman syndrome. Annals of Clinical and Translational Neurology, 2021;8(7):1433-1445. https://doi.org/10.1002/acn3.51385

Qiang L, Westover MB*, Zhang R*, Chu CJ*. Computational evidence for a competitive thalamocortical model of spikes and spindle activity in Rolandic epilepsy. Front Comp Neurosci. 2021; 15:680549. https://doi.org/10.3389/fncom.2021.680549

Wusthoff CJ, Sundaram V, Abend NS, Massey SL, Lemmon ME, Thomas C, McCulloch CE, Chang T, Soul JS, Chu CJ, Rogers EE, Bonifacio SL, Cilio MR, Glass HC, Shellhaas RA. Seizure control in neonates undergoing screening versus confirmatory EEG monitory. Neurology. 2021;97(6):e587-e596. https://doi.org/10.1212/WNL.0000000000012293

Glass HC, Soul JS, Chang T, Wusthoff CJ, Chu CJ, Massey SL, Abend NS, Lemmon M, Thomas C, Numis AL, Guillet R, Sturza J, McNarma NA, Rogers EE, Franck LS, McCulloch CE, Shellhaas RA. Safety of early discontinuation of antiseizure medication after acute symptomatic neonatal seizures. JAMA Neurology. 2021;78(7):817-825. https://doi.org/10.1001/jamaneurol.2021.1437

Shellhaas R, Wusthoff C, Numis A, Chu CJ, Massey S, Abend N, Soul J, Change T, Lemmon M, McNamara N, Guillet R, Franck L, Sturza J, Glass H. Early-life epilepsy after acute symptomatic neonatal seizures: a prospective multicenter study. Epilepsia. 202162(8):1871-1882. PMID: 34212365. https://doi.org/10.1111/epi.16978

Nadalin JK, Eden UT, Han X, Richardson RM, Chu CJ*, Kramer MA*. Application of a convolutional neural network for fully-automated detection of spike ripples in the scalp electroencephalogram. J Neurosci Methods. 2021;360:109239. https://doi.org/10.1016/j.jneumeth.2021.109239

Grinspan ZM, Knupp KG, Patel AD, Yozawitz EG, Wusthoff CJ, Wirrell E, Valencia I, Singhal NS, Nordlii DR, Mytinger JR, Mitchell W, Keator CG, Loddenkemper T, Hussain SA, Harini C, Gaillard WD, Fernandez IS, Coryell J, Chu CJ, Berg AT, Shellhaas RA. Comparative effectiveness of initial treatment for infantile spasms in a contemporary US cohort. Neurology. 2021; 97(12):e1217–28. https://doi.org/10.1212/WNL.0000000000012511

Lemmon ME, Glass HC, Shellhaas RA, Bark MC, Bansala S, Annisf D, Guerrierog JL, Piloni B, Wusthoff CJ, Chang T, Soul JS, Chu CJ, Thomas C, Massey SL, Abend NS, Rau S, Rogers EE, Franck LS, E on behalf of the Neonatal Seizure Registry. Family-centered care for children and families impacted by neonatal seizures: advice from parents. Arch Dis Childhood. 2021;124:26-32. https://doi.org/10.1016/j.pediatrneurol.2021.07.013

Yang JC, Paulk AC, Salami P, Lee SH, Ganji M, Soper DJ, Clearly D, Simon M, Maus D, Lee JW, Nahed BV, Jones PS, Cahill DP, Cosgrove GR, Chu CJ, Williams Z, Halgren E, Dayeh S, Cash SS. Microscale dynamics of electrophysiological markers of epilepsy. Clin Neurophysiol. 2021;S1388-2457(21):00670-2. https://doi.org/10.1016/j.clinph.2021.06.024

Wodeyar A, Schatza M, Widge AS, Eden UT, Kramer MA. A state space modeling approach to real-time phase estimation. Elife. 2021;10:e68803. https://doi.org/10.7554/eLife.68803

Herzberg EM, Machie M, Glass HC, Shellhaas RA, Wusthoff CJ, Chang T, Abend NS, Chu CJ, Cilio MR, Bonifacio SL, Massey SL. Seizure severity and treatment response in newborn infants with seizures attributed to intracranial hemorrhage. The Journal of pediatrics. 2022;242:121-8. https://doi.org/10.1016/j.jpeds.2021.11.012

Keene JC, Morgan LA, Abend NS, Bates SV, Bauer Huang SL, Chang T, Chu CJ, Glass HC, Massey SL, Ostrander B, Pardo AC, Press CA, Soul JS, Shellhaas RA, Thomas C, Natarajan N. Treatment of Neonatal Seizures: Comparison of Treatment Pathways from 11 Neonatal Intensive Care Units. Pediatr Neurol. 2021; [Epub ahead of print] PubMed PMID: 34750046. https://doi.org/10.1016/j.pediatrneurol.2021.10.004

Zhu X, Shappell H, Kramer MA, Chu CJ, Kolaczyk E. Inferring the type of phase transitions undergone in epileptic seizures using random graph hidden Markov models for percolation in noisy dynamic networks. arXiv: 2021. https://doi.org/10.48550/arXiv.2102.11948

Stoyell S, Baxter BS, McLaren J, Kwon H, Chinappen DM, Ostrowski L, Zhu L, Grieco JA, Kramer MA, Morgan AK, Emerton BC, Manoach DS, Chu CJ. Diazepam induced sleep spindle increase correlates with cognitive recovery in a child with epileptic encephalopathy: case report. BMC Neurol. 2021;21(1):355. https://doi.org/10.1186/s12883-021-02376-5

Kwon H, Kronemer SI, Christison-Lagay K, Khalaf A, Li J, Ding JZ, Freedman NC, Blumenfeld H. Early cortical signals in visual signal detection. Neuroimage. 2021;244:118608. https://doi.org/10.1016/j.neuroimage.2021.118608

Stacey W, Kramer M, Gunnarsdottir K, Gonzalez-Martinez J, Zaghloul K, Inati S, Sarma S, Stiso J, Khambhati AN, Bassett DS, Smith RJ. Emerging roles of network analysis for epilepsy. Epilepsy research. 2020;159:106255. https://doi.org/10.1016/j.eplepsyres.2019.106255

Ross EE*, Stoyell SM*, Kramer MA, Berg AT, Chu CJ. The natural history of seizures and neurophychiatric symptoms in childhood epilepsy with centrotemporal spikes (CECTS). Epilepsy Behav. 2020;103(Pt A):106437. https://doi.org/10.1016/j.yebeh.2019.07.038

Smith EH, Merricks EM, Liou J-Y, Casadei C, Melloni L, Friedman D, Doyle W, Goodman RR, Emerson RG, McKhann GM, Sheth SA, Rolston J, Schevon CA. Dual mechanisms of ictal high frequency oscillations in rhythmic onset seizures. Scientific Reports. 2020; 10(1): 19166. https://doi.org/10.1101/2020.01.09.20017053

Franck LS, Shellhaas RA, Lemmon M, Sturza J, Soul JS, Chang T, Wusthoff CJ, Chu CJ, Massey SL, Abend NS, Thomas C, Rogers EE, McCulloch CE, Grant K, Grossbauer L, Pawlowski K, Glass HC. Associations between Infant and Parent Characteristics and Measures of Family Well-Being in Neonates with Seizures: A Cohort Study. J Pediatr. 2020;221:64-71.e4. https://doi.org/10.1016/j.jpeds.2020.02.024

Rubin DB, Angelini B, Shoukat M, Chu CJ, Zafar SF, Westover MB, Cash SS, Rosenthal ES. Electrographic predictors of successful weaning from anaesthetics in refractory status epilepticus. Brain. 2020;143(4):1143-57. https://doi.org/10.1093/brain/awaa069

Martinet LE*, Kramer MA*, Viles W, Perkins N, Spencer E, Chu CJ, Cash SS, Kolaczyk ED. Robust dynamic community tracking with applications in human brain functional networks. Nat Comm. 2020;131(8):1782-97. https://doi.org/10.1038/s41467-020-16285-7

Lemmon M, Glass H, Shellhaas RA, Barks MC, Bailey B, Grank K, Grossbauer L, Pawlowski K, Wusthoff CJ, Chant T, Soul J, Chu CJ, Thomas C, Massey SL, Abend NS, Rogers EE, Franck LS. Parent experience of caring for neonates with seizures. Arch Dis Child Fetal Neonatal Ed. 2020;105:634-9. https://doi.org/10.1136/archdischild-2019-318612

Thorn EL, Ostrowski LM, Chinappen DM, Jing J, Westover MB, Stufflebeam SM, Kramer MA, Chu CJ. Persistent abnormalities in Rolandic thalamocortical white matter circuits in childhood epilepsy with centrotemporal spikes. Epilepsia. 2020;61(11):2500-8. https://doi.org/10.1111/epi.16681

Yoo HS, Chung SJ, Lee YH, Ye BS, Sohn YH, Kwon H* , Lee PH*. Urate is closely linked to white matter integrity in multiple system atrophy. Ann Clin Transl Neurol. 2020;7(6):1029–1039. *Equal contributions as a corresponding author. https://doi.org/10.1002/acn3.51073

Salami P, Peled N, Nadalin JK, Martinet LE, Kramer MA, Lee JW, Cash SS. Seizure onset location shapes dynamics of initiation. Clinical Neurophysiology. 2020;131(8):1782-97. https://doi.org/10.1016/j.clinph.2020.04.168

Kim BR, Kwon H, Chun MY, Park KD, Lim SM, Jeong JH, Kim GH. White matter integrity is associated with the amount of physical activity in older adults with superaging. Front Aging Neurosci. 2020;12:549983. https://doi.org/10.3389/fnagi.2020.549983

Glass HC, Grinspan ZM, Li Y, McNamara NA, Chang T, Chu CJ, Massey SL, Abend NS, Lemmon ME, Thomas C, McCulloch CE, Shellhaas RA. Risk for infantile spasms after acute symptomatic neonatal seizures. Epilepsia. 2020;105:634-9. https://doi.org/10.1111/epi.16749

Lemmon ME, Bonifacio SL, Shellhaas RA, Wusthoff CJ, Greenberg RG, Souls JS, Chang T, Chu CJ, Bates S, Massey SL, Abend NS, Cilio MR, Glass HC. Characterization of death in infants with neonatal seizures. Pediatr Neurol. 2020;113:21-5. https://doi.org/10.1016/j.pediatrneurol.2020.08.002

Kim KW, Kwon H, Kim YE, Yoon CW, Kim YJ, Kim YB, Lee JM, Yoon WT, Kim HJ, Lee JS, Jang YK, Kim YS, Jang H, Ki CS, Youn YC, Shin BS, Bang OY, Kim GM, Chung CS, Kim SJ, Na DR, Duering M, Cho H, Seo SW. Multimodal imaging analyses in patients with genetic and sporadic forms of small vessel disease. Sci Rep. 2019;9(1):787. https://doi.org/10.1038/s41598-018-36580-0

Glass HC, Soul JS, Chu CJ, Massey SL, Wusthoff CJ, Chang T, Cilio MR, Bonifacio SL, Abend NS, Thomas C, Lemmon M, McCulloch CE, Shellhaas RA; Neonatal Seizure Registry study group. Response to antiseizure medications in neonates with acute symptomatic seizures. Epilepsia. 2019;60(3):e20-e4. https://doi.org/10.1111/epi.14671

Kwon H, Choi YH, Lee JM. A Physarum centrality measure of the human brain network. Sci Rep. 2019;9(1):5907. Code available at: https://github.com/Hunki-Kwon/Physarum-Centrality. https://doi.org/10.1038/s41598-019-42322-7

Gritton HJ, Howe WM, Romano MF, DiFeliceantonio AG, Kramer MA, Saligrama V, Bucklin ME, Zemel D, Han X. Unique contributions of parvalbumin and cholinergic interneurons in organizing striatal networks during movement. Nature neuroscience. 2019;22(4):586-97. https://doi.org/10.1038/s41593-019-0341-3

Chung SJ, Park YH, Yun HJ, Kwon H, Yoo HS, Sohn YH, Lee JM, Lee PH. Clinical relevance of amnestic versus nonamnestic MCI subtyping in Parkinson's disease. Eur J Neurol. 2019;26(5):766–773. https://doi.org/10.1111/ene.13886

Youn JH, Ryu SH, Lee JY, Park S, Cho SJ, Kwon H, Yang JJ, Lee JM, Lee J, Kim S, Livingston G, Yoon DH. Brain structural changes after multi-strategic metamemory training in older adults with subjective memory complaints: A randomized controlled trial. Brain Behav. 2019;9(5):e021278. https://doi.org/10.1002/brb3.1278

Kramer MA, Ostrowski LM, Song DY, Thorn EL, Stoyell SM, Parnes M, Xiao G, Staley KJ, Stufflebeam SM, Chu CJ. Scalp recorded spike ripples predict seizure risk in childhood epilepsy better than spikes. Brain. 2019;142(5):1296-309. https://doi.org/10.1093/brain/awz059

Tryba AK¹, Merricks EM¹, Lee S, Pham T, Cho S, Nordli DR Jr, Eissa TL, Goodman RR, McKhann GM, Emerson RG, Schevon CA, van Drongelen W. Role of paroxysmal depolarization in focal seizure activity. Journal of Neurophysiology. 2019;122:1861–1873. Co –first author¹. https://doi.org/10.1152/jn.00392.2019

Schevon CA, Tobochnik S, Eissa TL, Merricks EM, Gill BJ, Bateman LM, McKhann, GM, Emerson RG, Trevelyan AJ. Multiscale recordings reveal the dynamic spatial structure of human seizures. Neurobiology of Disease. 2019;127:303-311. https://doi.org/10.1016/j.nbd.2019.03.015

Chung SJ, Yoo HS, Lee YH, Lee HS, Ye BS, Sohn YH, Kwon H^* , Lee PH*. Frontal atrophy as a marker for dementia conversion in Parkinson's disease with mild cognitive impairment. Hum Brain Mapp. 2019;40(13):3784- 3794. ^*Equal contributions as a corresponding author. https://doi.org/10.1002/hbm.24631

Li J, Kronemer SI, Herman WX, Kwon H, Ryu JH, Micek C, Wu Y, Gerrard J, Spencer DD, Blumenfeld H. Default mode and visual network activity in an attention task: Direct measurement with intracranial EEG. Neuroimage. 2019;201:116003. https://doi.org/10.1016/j.neuroimage.2019.07.016

Song D, Ross EE, Xie W, Ostrowski LM, Thorn EL, Sheehan S, Stufflebeam SM, Kramer MA, Chu CJ. Beta rhythm power in the perirolandic region correlates with time from seizure. Brain and Behavior. 2019;9(3):e01237. https://doi.org/10.1002/brb3.1237

Peters JM, Hyde DE, Chu CJ, Boom M, Scherrer B, Madsen JR, Stone SS, Ouaalam H, Prabhu SP, Sahin M. Warfield SK. Lesion-Constrained Electrical Source Imaging: A Novel Approach in Epilepsy Surgery for Tuberous Sclerosis Complex. J Clin Neurophysiol. 2020;3791:79-86. https://doi.org/10.1097/WNP.0000000000000615

Berg AR, Wusthoff C, Shellhaas RA, Loddenkemper T, Grinspan ZM, Saneto RP, Knupp KG, Patel A, Sullivan JE, Kossoff EH, Chu CJ, Massey S, Valencia I, Keator C, Wirrel EC Coryell J, Millichap JJ, Gaillard WD. Immediate outcomes in early life epilepsy: A conte,porary account. Epilepsy Behav 2019; 97:44-50. https://doi.org/10.1016/j.yebeh.2019.05.011

Ostrowski LM, Song DY, Thorn EL, Ross EE, Stoyell SM, Eden UT, Kramer MA, Emerton BC, Morgan AK, Stufflebeam SM, Chu CJ. Dysmature superficial white matter microstructure in developmental focal epilepsy. Brain Commun. 2019;1(1):fcz002. https://doi.org/10.1093/braincomms/fcz002

Jing J, Herlopian A, Karakis I, Ng M, Halford JJ, Lam A, Maus D, Chan F, Dolatshahi M, Muniz C, Chu C, Sacca V, Pathmanathan J, Ge W, Sun H, Dauwels J, Cole AJ, Hoch DB, Cash SS, Westover MB. Interrater Reliability of Experts in Identifying Interictal Epileptiform Discharges in Electroencephalograms. JAMA Neurol. 2019;77(1):49-57. https://doi.org/10.1001/jamaneurol.2019.3531

Nadalin JK, Martinet LE, Blackwood EB, Lo MC, Widge AS, Cash SS, Eden UT, Kramer MA. A statistical framework to assess cross-frequency coupling while accounting for confounding analysis effects. Elife. 2019;8:e44287. https://doi.org/10.7554/eLife.44287

Jing J, Sun H, Kin JA, Herlopian A, Karakis I, Ng M, Halford JJ, Maus D, Chan F, Dolatshahi M, Muniz C, Chu C, Sacca V, Pathmanathan J, Ge W, Dauwels J, Lam A, Cole AJ, Cash SS, Westover MB. Development of Expert-Level Automated Detection of Epileptiform Discharges During Electroencephalogram Interpretation. JAMA Neurol. 2019;77(1):103-8. https://doi.org/10.1001/jamaneurol.2019.3485

Worden L, Chinappen DK, Gold J, De Carvalho Paixao LC, Kramer MA, Westover MB, Chu CJ. The probability of seizures during continuous EEG monitoring in high-risk neonates. Epilepsia 2019;60(12):2508-18. https://doi.org/10.1001/jamaneurol.2019.3485
   Highlighted in the Editorial:
    Kotagal, P. (2020) ‘Continuous EEG Monitoring in Neonates: One Size Does Not Fit All’, Epilepsy Currents. https://doi.org/10.1177/1535739720923292

Park S, Ryu SH, Yoo YJ, Yang JJ, Kwon H, Youn JH, Lee JM, Cho SJ, Lee JY. Neural predictors of cognitive improvement by multi-strategic memory training based on metamemory in older adults with subjective memory complaints. Sci Rep. 2018;8(1):1095. https://doi.org/10.1038/s41598-018-19390-2

Park KH, Chung WH, Kwon H, Lee JM. Evaluation of cerebral white matter in prelingually deaf children using diffusion tensor imaging. Biomed Res Int. 2018;2018:7. https://doi.org/10.1155/2018/6795397

Banerjee G, Jang H, Kim HJ, Kim ST, Kim JS, Lee JH, Im K, Kwon H, Lee JM, Na DL, Seo SW, Werring DJ. Total MRI small vessel disease burden correlates with cognitive performance, cortical atrophy, and network measures in a memory clinic population. J Alzheimers Dis. 2018;63(4):1485–1497. https://doi.org/10.3233/JAD-170943

González-Ramírez LR, Kramer MA. The effect of inhibition on the existence of traveling wave solutions for a neural field model of human seizure termination. Journal of computational neuroscience. 2018;44(3):393-409. https://doi.org/10.1007/s10827-018-0685-9

Naftulin JS, Ahmed OJ, Piantoni G, Eichenlaub JB, Martinet LE, Kramer MA, Cash SS. Ictal and preictal power changes outside of the seizure focus correlate with seizure generalization. Epilepsia. 2018;59(7):1398-409. https://doi.org/10.1111/epi.14449

Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff CJ, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Epilepsy. JAMA Pediatr 2018;172:352-60. https://doi.org/10.1001/jamapediatrics.2017.5211

Berg AT, Chakravorty S, Joh S, Grinspan ZM, Shellhaas RA, Saneto RP, Poduri A, Wirrell EC, Coryell J, Chu CJ, Mytinger JR, Gaillard WD, Valencia I, Knupp KG, Loddenkemper T, Sullivan JE, Millichap JJ, Keator C, Wusthoff CJ, Ryan N, Dobyns WB, Hedge M. Why West? A comparative analysis of the clinical, genetic, and biological features in infants with and without infantile spasms. PlosOne. 2018;13(3):e0193599. https://doi.org/10.1371/journal.pone.0193599

Kim YS, Jang H, Kim SJ, Cho SH, Kim SE, Kim ST, Kim HJ, Moon SH, Ewers M, Im K, Kwon H, Na DL, Seo SW. Vascular effects on depressive symptoms in cognitive impairment. J Alzheimers Dis. 2018;65(2):597–605. https://doi.org/10.3233/JAD-180394

Coryell J, Gaillard WD, Shellhaas RA, Grinspan ZM, Wirrell EC, Knupp KG, Wusthoff CJ, Keator C, Sullivan JE, Loddenkemper T, Patel A, Chu CJ, Massey S, Novotny EJ Jr, Saneto RP, Berg AT. Neuroimaging of Early Life Epilepsy. Pediatrics. 2018;142(3). https://doi.org/10.1542/peds.2018-0672

Spencer E, Martinet LE, Eskandar EN, Chu CJ, Kolaczyk ED, Cash SS, Eden UT, Kramer MA. A procedure to increase the power of Granger-casual analysis through temporal smoothing. J Neurosci Methods. 2018;308:48-61. https://doi.org/10.1016/j.jneumeth.2018.07.010 

Xie W, Ross EE, Kramer MA, Chu CJ. Timing matters: impact of anticonvulsant drug treatment and spikes on seizure risk in benign epilepsy with centrotemporal spikes. Epilepsia Open. 2018;3:409-17. https://doi.org/10.1002/epi4.12248

den Bakker H, Sidorov MS, Fan Z, Lee DJ, Bird LM, Chu CJ, Philpot BD. Abnormal coherence and sleep composition in children with Angelman syndrome: a retrospective EEG study. Mol Autism. 2018;9:32. https://doi.org/10.1186/s13229-018-0214-8

Basu I, Crocker B, Farnes K, Robertson MM, Paulk AC, Vallejo DI, Dougherty DD, Cash SS, Eskandar EN, Kramer MA, Widge AS. A neural mass model to predict electrical stimulation evoked responses in human and non-human primate brain. Journal of neural engineering. 2018;15(6):066012. https://doi.org/10.1088/1741-2552/aae136

Widge AS, Ellard KK, Paulk AC, Basu I, Yousefi A, Zorowitz S, Gilmour A, Afzal A, Deckersbach T, Cash SS, Kramer MA. Treating refractory mental illness with closed-loop brain stimulation: progress towards a patient-specific transdiagnostic approach. Experimental neurology. 2017;287:461-72. https://doi.org/10.1016/j.expneurol.2016.07.021

Shellhaas RA, Wusthoff CJ, Tsuchida T, Glass JC, Chu CJ, Massey S, Soul JS, Wiwattanadittakun N, Abend N, Cilio MR. Management variability for treatment of seizures in neonates: a multi-center cohort study. J Pediatrics. 2017; 181:298-301. https://doi.org/10.1016/j.jpeds.2016.10.039

Chu CJ, Chan A, Song D, Staley KJ, Stufflebeam SM, Kramer MA. A semi-automated method for rapid detection of ripple events on interictal voltage discharges in the scalp electroencephalogram. J Neurosci Methods. 2017; 277:46-55. https://doi.org/10.1016/j.jneumeth.2016.12.009

Shellhaas RA, Chang T, Wusthoff CJ, Soul JS, Massey SL, Chu CJ, Cilio MR, Bonifacio SL, Abend NS, Tsuchida TN, Glass HC; Neonatal Seizure Registry Study Group. Treatment Duration After Acute Symptomatic Seizures in Neonates: A Multicenter Cohort Study. J Pediatr. 2017;181:298-301. https://doi.org/10.1016/j.jpeds.2016.10.039

Chung SJ, Choi YH, Kwon H, Park YH, Yun HJ, Yoo HS, Lee PH, Lee PH, Lee PH. Sleep disturbance may alter white matter and resting state functional connectivity in Parkinson’s disease. Sleep. 2017 Mar;40(3):zsx009. https://doi.org/10.1093/sleep/zsx009

Martinet LE, Fiddyment G, Madsen JR, Eskandar EN, Truccolo W, Eden UT, Cash SS, Kramer MA. Human seizures couple across spatial scales through travelling wave dynamics. Nature communications. 2017;8(1):14896. https://doi.org/10.1038/ncomms14896

Kwon H, Choi YH, Seo SW, Lee JM. Scale-integrated network hubs of the white matter structural network. Sci Rep. 2017;7(1):42849. https://doi.org/10.1038/s41598-017-02342-7

Shellhaas RA, Wusthoff CC, Tsuchida T, Glass HC, Chu CJ, Massey S, Soul JS, Wiwattanadittakun N, Abend N, Cilio MR. Profile of neonatal epilepsies: characteristics of a prospective US cohort. Neurology. 2017;89:893-899. https://doi.org/10.1212/WNL.0000000000004284

Jang H* , Kwon H* , Yang JJ, Kim YS, Kim KW, Lee JS, Jang YK, Kim ST, Lee JH, Na DL, Seo SW, Lee JM, Kim HJ. Correlations between gray matter and white matter in pure Alzheimer’s disease, pure subcortical vascular dementia, and mixed dementia. Sci Rep. 2017;7(1):9541. *Equal contributions as a first author. https://doi.org/10.1038/s41598-017-10074-x

Glass HC, Shellhaas RA, Tsuchida TN, Chang T, Wusthoff CJ, Chu CJ, Cilio MR, Bonifacio SL, Massey SL, Abend NS, Soul JS; Neonatal Seizure Registry study group. Seizures in Preterm Neonates: A Multicenter Observational Cohort Study. Pediatr Neurol. 2017;72:19-24. https://doi.org/10.1016/j.pediatrneurol.2017.04.016

Shellhaas RA, Berg AT, Grinspan ZM, Wusthoff CJ, Millichap JJ, Loddenkemper T, Coryell J, Saneto RP, Chu CJ, Joshi SM, Sullivan JE, Knupp KG, Kossoff EH, Keator C, Wirrell EC, Mytinger JR, Valencia I, Massey S, Gaillard WD. Initial Treatment for Nonsyndromic Early-Life Epilepsy: An Unexpected Consensus. Pediatr Neurol. 2017;75:73-9. https://doi.org/10.1016/j.pediatrneurol.2017.06.011

Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff CJ, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S. Early-Life Epilepsies and the Emerging Role of Genetic Testing. JAMA Pediatr. 2017;171(9):863-71. https://doi.org/10.1001/jamapediatrics.2017.1743

Edlow BL, Chatelle C, Spencer CA, Chu CJ, Bodien YG, O’Connor KL, Hirschberg RE, Hochberg LR, Giacino JT, Rosenthal ES, Wu O. Early detection of consciousness in patients with acute severe traumatic brain injury. Brain. 2017;140(9):2399-414. https://doi.org/10.1093/brain/awx176

Tang W, Liu H, Douw L, Kramer MA, Eden UT, Hämäläinen MS, Stufflebeam SM. Dynamic connectivity modulates local activity in the core regions of the default-mode network. Proceedings of the National Academy of Sciences. 2017;114(36):9713-8. https://doi.org/10.1073/pnas.1702027114

Østergaard J, Kramer MA, Eden UT. Capturing spike variability in noisy Izhikevich neurons using point process generalized linear models. Neural computation. 2017;30(1):125-48. https://doi.org/10.1162/neco_a_01030

Sidorov MS, Deck GM, Dolatshahi M, Thibert RL, Bird LM, Chu CJ^*, Philpot BD^* (co-last authors). Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome. J Neurodev Disord. 2017;9:17. https://doi.org/10.1186/s11689-017-9195-8

Demarest ST, Shellhaas RA, Gaillard WD, Keator C, Nickels KC, Hussain SA, Loddenkemper T, Patel AD, Saneto RP, Wirrell E, Sánchez Fernández I, Chu CJ, Grinspan Z, Wusthoff CJ, Joshi S, Mohamed IS, Stafstrom CE, Stack CV, Yozawitz E, Bluvstein JS, Singh RK, Knupp KG; Pediatric Epilepsy Research Consotrium. The impact of hypsarrhythmia on infantile spasms treatment response: Observational cohort study from the National Infantile Spasms Consortium. Epilepsia. 2017;58(12):2098-103. https://doi.org/10.1111/epi.13937

Park S, Lee JM, Kim JW, Kwon H, Choi SC, Han DH, Cheong JH, Kim BN. Increased white matter connectivity in traumatized children with attention-deficit hyperactivity disorder. Psychiatry Res Neuroimaging. 2016;247:57–63. https://doi.org/10.1016/j.pscychresns.2015.09.012

Kim GH, Seo SW, Jung K, Kwon H, Kim OH, Roh JH, Kim MJ, Lee BH, Hwang JW, Lee JM, Jeong JH, Na DL. The neural correlates of motor intentional disorders in patients with subcortical vascular cognitive impairment. J Neurol. 2016;263(1):89–99. https://doi.org/10.1007/s00415-015-7946-6

Jang YK, Kwon H, Kim YJ, Jung NY, Lee JS, Lee J, Chin J, Im K, Kim YJ, Noh Y, Kim GH, Ko ED, Kim JS, Kim ST, Kim JH, Lee JH, Ewers M, Weiner MW, Na DL, Seo SW, Kim HJ. Early- versus late-onset subcortical vascular cognitive impairment. Neurology. 2016;86(6):527–34. https://doi.org/10.1212/WNL.0000000000002357

Kim HJ, Kwon H, Lee JM, Cho H, Kim YJ, Lee JH, Kim HE, Kim SJ, Lee JS, Jang YK, Kim ST, Choe YS, Kim YJ, Na DL, Seo SW. Gray and white matter changes linking cerebral small vessel disease to gait disturbances. Neurology. 2016;86(13):1199–207. https://doi.org/10.1212/WNL.0000000000002516

Smith EH, Liou JY, Davis TS, Merricks EM, Kellis SS, Weiss SA, Greger B, House PA, McKhann GM, Goodman RR, Emerson RG, Bateman LM, Trevelyan AJ, Schevon CA. The ictal wavefront is the spatiotemporal source of discharges during spontaneous human seizures. Nature Communications. 2016; 7(1): 11098. https://doi.org/10.1038/ncomms11098

Yang JJ, Kwon H, Lee JM. Complementary characteristics of correlation patterns in morphometric correlation networks of cortical thickness, surface area, and gray matter. Sci Rep. 2016;6:26682. https://doi.org/10.1038/srep26682

Viles W, Ginestet CE, Tang A, Kramer MA, Kolaczyk ED. Percolation under noise: Detecting explosive percolation using the second-largest component. Physical Review E. 2016;93(5):052301. https://doi.org/10.1103/PhysRevE.93.052301

Kim GH, Im K, Kwon H, Seo SW, Ye BS, Cho H, Noh Y, Lee JM, Park SE, Kim HJ, Kim ST, Kim JS, Choe YS, Jeong JH, Na DL. Higher physical activity is associated with increased attentional network connectivity in the healthy elderly. Front Aging Neurosci. 2016;8:198. https://doi.org/10.3389/fnagi.2016.00198

Kim HJ, Yang JJ, Kwon H, Kim C, Lee JM, Kim YJ, Jung YK, Chin J, Seo SW, Woo SW, Choe YS, Lee KH, Kim ST, Kim JH, Lee JH, Ewers M, Weiner MW, Na DL, Seo SW. Relative impact of amyloid-β, lacunes, and downstream imaging markers on cognitive trajectories. Brain. 2016;139(9):2516–27. https://doi.org/10.1093/brain/aww148

Glass HC, Shellhaas RA, Wusthoff CJ, Chang T, Abend NS, Chu CJ, Cilio RC, Glidden DV, Bonafacio SL, Massey S, Tsuchida TN, Silvertein FS, Soul JS. Contemporary profile of seizures in neonates: A prospective cohort study of the Neonatal Seizure Registry. J Pediatrics. 2016;174:98-103. https://doi.org/10.1016/j.jpeds.2016.03.035

Knupp KG, et al and the Pediatric Epilepsy Research Consortium. Response to treatment in a prospective national infantile spasms cohort. Annals of Neurology. 2016; 79: 475-84. https://doi.org/10.1002/ana.24594

Knupp KG, Leister E, Coryell J, Nickels KC, Ryan N, Juarez-Colunga E, Gaillard WD, Mytinger JR, Berg AT, Millichap J, Nordi DR, Joshi S, Shellhaas RA, Loddenkemper T, Dlugos D, Wirrell E, Sullivan J, Hartman AL, Kossoff EH, Grinspan ZM, Hamikawa L, and the Pediatric Epilepsy Research Consortium. Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort. Epilepsia. 2016;57(11):1834-1842. https://doi.org/10.1111/epi.13557

Vo T, Kramer MA, Kaper TJ. Amplitude-modulated bursting: a novel class of bursting rhythms. Physical review letters. 2016;117(26):268101. https://doi.org/10.1103/PhysRevLett.117.268101

Moon Y, Moon WJ, Kwon H, Lee JM, Han SH. Vitamin D Deficiency Disrupts Neuronal Integrity in Cognitively Impaired Patients. J Alzheimers Dis, 2015;45(4):1089-96. https://doi.org/10.3233/JAD-143063

Youn J, Lee JM, Kwon H, Kim JS, Son TO, Cho JW. Alterations of mean diffusivity of pedunculopontine nucleu pathway in Parkinson’s disease patients with freezing of gait. Parkinsonism Relat Disord. 2015;21(1):12-7. https://doi.org/10.1016/j.parkreldis.2014.10.003

Aoi MC, Lepage KQ, Kramer MA, Eden UT. Rate-adjusted spike–LFP coherence comparisons from spike-train statistics. Journal of neuroscience methods. 2015;240:141-53. https://doi.org/10.1016/j.jneumeth.2014.11.012

Yaffe RB, Borger P, Megevand P, Groppe DM, Kramer MA, Chu CJ, Santaniello S, Meisel C, Mehta AD, Sarma SV. Physiology of functional and effective networks in epilepsy. Clinical Neurophysiology. 2015;126(2):227-36. https://doi.org/10.1016/j.clinph.2014.09.009

González-Ramírez LR, Ahmed OJ, Cash SS, Wayne CE, Kramer MA. A biologically constrained, mathematical model of cortical wave propagation preceding seizure termination. PLoS computational biology. 2015;11(2):e1004065. https://doi.org/10.1371/journal.pcbi.1004065

Shafi M, Vernet M, Klooster D, Barnard M, Romatoski K, Westover MB, Chu CJ, Boric K, Christodoulou J, Gabrieli J, Whitfield-Gabrieli S, Pascuel-Leone A, Chang B. Physiological consequences of abnormal connectivity in a developmental epilepsy. Annals of Neurology. 2015;7793:487-503. https://doi.org/10.1002/ana.24343

Chu CJ, Tanaka N, Diaz J, Edlow B, Wu O, Hamalainen M, Stufflebean SM, Cash SS, Kramer MA. EEG functional connectivity is partially predicted by underlying white matter connectivity. Neuroimage 2015;108:23-33. https://doi.org/10.1016/j.neuroimage.2014.12.033

Finzi AC, Abramoff RZ, Spiller KS, Brzostek ER, Darby BA, Kramer MA, Phillips RP. Rhizosphere processes are quantitatively important components of terrestrial carbon and nutrient cycles. Global change biology. 2015;21(5):2082-94. https://doi.org/10.1111/gcb.12816

Kim GH, Jeon S, Im K, Kwon H, Lee BH, Kim GY, Jeong H, Han NE, Seo SW, Cho H, Noh Y, Park SE, Kim HJ, Hwang JW, Yoon CW, Jin SH, Ye BS, Chin JH, Kim JH, Suh MK, Lee JM, Kim ST, Kim MT, Heilman KM, Jeong JH, Na DL. Structural brain changes after traditional and robot-assisted multi-domain cognitive training in community-dwelling healthy elderly. PLoS One. 2015;10(4):e0123251. https://doi.org/10.1371/journal.pone.0123251

Kim YJ, Kwon H, Lee JM, Kim YJ, Kim HJ, Jung NY, Kim ST, Lee KH, Na DL, Seo SW. White matter microstructural changes in pure Alzheimer’s disease and subcortical vascular dementia. Eur J Neurol. 2015;22(4):709-716. https://doi.org/10.1111/ene.12645

Martinet LE, Ahmed OJ, Lepage KQ, Cash SS, Kramer MA. Slow spatial recruitment of neocortex during secondarily generalized seizures and its relation to surgical outcome. Journal of Neuroscience. 2015;35(25):9477-90. https://doi.org/10.1523/JNEUROSCI.0049-15.2015

Matlis S, Boric K, Chu CJ, Kramer MA. Robust disruptions in electroencephalogram cortical oscillations and large-scale functional networks in autism. BMC neurology. 2015;15(1):97. https://doi.org/10.1186/s12883-015-0355-8

Kim HJ, Seo SW, Jang JW, Lee JI, Kim CH, Chin J, Choi SJ, Kwon H, Yun HJ, Lee JM, Kim ST, Choe YS, Lee KH, Na DL. Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: A phase I clinical trial. Alzheimers Dement Transl Res Clin Interv. 2015;1(2):95-102. https://doi.org/10.1016/j.trci.2015.06.007

Kim HJ, Im K, Kwon H, Lee JM, Kim C, Kim YJ, Jung NY, Cho H, Ye BS, Noh Y, Kim GH, Ko ED, Kim JS, Choe YS, Lee KH, Kim ST, Lee JH, Ewers M, Weiner MW, Na DL, Seo SW. Clinical effect of white matter network disruption related to amyloid and small vessel disease. Neurology. 2015;85(1):63-70. https://doi.org/10.1212/WNL.0000000000001705

Kim HJ, Im K, Kwon H, Lee JM, Ye BS, Kim YJ, Cho H, Choe YS, Lee KH, Kim ST, Kim JS, Kim JH, Na DL, Seo SW. Effects of amyloid and small vessel disease on white matter network disruption. J Alzheimers Dis. 2015;44(3):963-75. https://doi.org/10.3233/JAD-141623

Park S, Lee JM, Baik Y, Kim KH, Yun HJ, Kwon H, Jung YK, Kim BN. A preliminary study of the effects of an arts education program on executive function, behavior, and brain structure in a sample of nonclinical school-aged children. J Child Neurol. 2015;30(13):1757-66. https://doi.org/10.1177/0883073815579710

Alfonsa H, Merricks EM, Codadu NK, Cunningham MO, Deisseroth K, Racca C, Trevelyan AJ. The contribution of raised intraneuronal chloride to epileptic network activity. Journal of Neuroscience. 2015; 35(20), 7715–7726. https://doi.org/10.1523/JNEUROSCI.4105-14.2015

Trevelyan AJ, Muldoon SF, Merricks EM, Racca C, Staley K. The role of inhibition in epileptic networks. Journal of Clinical Neurophysiology. 2015; 32(3), 227–234. https://doi.org/10.1097/WNP.0000000000000160

Merricks EM, Smith EH, McKhann GM, Goodman RR, Bateman LM, Emerson RG, Schevon CA, Trevelyan AJ. Single unit action potentials in humans and the effect of seizure activity. Brain. 2015; 138(10), 2891–2906. https://doi.org/10.1093/brain/awv208

Matlis S, Kramer MA, Chu CJ. Disruptions in cortical oscillations and large-scale functional networks in autism. BMC Neurology. 2015;15(1):97-105. https://doi.org/10.1186/s12883-015-0355-8

Voytek B, Kramer MA, Case J, Lepage KQ, Tempesta ZR, Knight RT, Gazzaley A. Age-related changes in 1/f neural electrophysiological noise. Journal of neuroscience. 2015;35(38):13257-65. https://doi.org/10.1523/JNEUROSCI.2332-14.2015

Meng L, Kramer MA, Middleton SJ, Whittington MA, Eden UT. A unified approach to linking experimental, statistical and computational analysis of spike train data. PloS one. 2014;9(1):e85269. https://doi.org/10.1371/journal.pone.0085269

Stephen EP, Lepage KQ, Eden UT, Brunner P, Schalk G, Brumberg JS, Guenther FH, Kramer MA. Assessing dynamics, spatial scale, and uncertainty in task-related brain network analyses. Frontiers in computational neuroscience. 2014;8:31. https://doi.org/10.3389/fncom.2014.00031

Chu CJ, Leahy JT, Pathmanathan J, Kramer MA, Cash SS. The maturation of cortical sleep rhythms and networks over early development. Clin Neurophys. 2014; 125(7):1360-70. https://doi.org/10.1016/j.clinph.2013.11.028

Ahmed OJ, Kramer MA, Truccolo W, Naftulin JS, Potter NS, Eskandar EN, Cosgrove GR, Blum AS, Hochberg LR, Cash SS. Inhibitory single neuron control of seizures and epileptic traveling waves in humans. BMC Neuroscience. 2014;15(Suppl 1):F3. https://doi.org/10.1186/1471-2202-15-S1-F3

Kopell NJ, Gritton HJ, Whittington MA, Kramer MA. Beyond the connectome: the dynome. Neuron. 2014;83(6):1319-28. https://doi.org/10.1016/j.neuron.2014.08.016

Lepage KQ, Kramer MA, Chu CJ. A statistically robust EEG re-referencing procedure to mitigate reference effect. J Neurosci Methods. 2014;235:101‐116. https://doi.org/10.1016/j.jneumeth.2014.05.008

Westover MB, Shafi MM, Bianchi MT, Veras Rocha Moura LM, O’Rourke D, Rosenthal E, Chu CJ, Hoch DB, Kilbride R, Cole AJ, Cash SS. The probability of seizure detection among critically ill adults. Clin Neurophysiol. 2014;126:463-71. https://doi.org/10.1016/j.clinph.2014.05.037

Shore JC, Chu CJ, Bianchi MT. Spontaneous power law degree distributions and turbulent dynamics in flow networks. Social Networks. 2013;35:116-123. https://doi.org/10.1016/j.socnet.2013.01.005

Drake JE, Darby BA, Giasson MA, Kramer MA, Phillips RP, Finzi AC. Stoichiometry constrains microbial response to root exudation-insights from a model and a field experiment in a temperate forest. Biogeosciences. 2013;10(2):821-38. https://doi.org/10.5194/bg-10-821-2013

Lepage KQ, Gregoriou GG, Kramer MA, Aoi M, Gotts SJ, Eden UT, Desimone R. A procedure for testing across-condition rhythmic spike-field association change. Journal of neuroscience methods. 2013;213(1):43-62. https://doi.org/10.1016/j.jneumeth.2012.10.010

Lepage KQ, Ching S, Kramer MA. Inferring evoked brain connectivity through adaptive perturbation. Journal of computational neuroscience. 2013;34(2):303-18. https://doi.org/10.1007/s10827-012-0422-8

Lepage KQ, Kramer MA, Eden UT. Some sampling properties of common phase estimators. Neural computation. 2013;25(4):901-21. https://doi.org/10.1007/s10827-012-0422-8

Gerhard F, Kispersky T, Gutierrez GJ, Marder E, Kramer M, Eden U. Successful reconstruction of a physiological circuit with known connectivity from spiking activity alone. PLoS computational biology. 2013;9(7):e1003138. https://doi.org/10.1371/journal.pcbi.1003138

Ryoo NY, Yoon BN, Yoon CW, Ahn JH, Choi JY, Lim MK, Kwon H, Park JS, Lee JM, Choi SH. Diffusion Tensor Imaging Changes Correlate with Clinical Progression in Vascular Mild Cognitive Impairment and Vascular Dementia of Subcortical Type. Dementia and Neurocognitive Disorders. 2013;12(3):61-71. https://doi.org/10.12779/dnd.2013.12.3.61

Kramer MA, Eden UT. Assessment of cross-frequency coupling with confidence using generalized linear models. Journal of Neuroscience Methods. 2013;220(1):64-74. https://doi.org/10.1016/j.jneumeth.2013.08.006

Chung SJ, Kwon H, Lee DK, Hong JY, Sunwoo MK, Sohn YH, Lee JM, Lee PH. Neuroanatomical Heterogeneity of Essential Tremor According to Propranolol Response. PLoS One. 2013;8(12):e84054. https://doi.org/10.1371/journal.pone.0084054

Kaper TJ, Kramer MA, Rotstein HG. Introduction to focus issue: rhythms and dynamic transitions in neurological disease: modeling, computation, and experiment. Chaos: An Interdisciplinary Journal of Nonlinear Science. 2013;23(4). https://doi.org/10.1063/1.4856276

Van Eeghan AM, Chu CJ, Pulsifer MB, Camposano SE, Thiele EA. Cognitive and adaptive development of patients with tuberous sclerosis complex: A retrospective, longitudinal investigation. Epilepsy Beh. 2012;23(1):10-5. PMID: 22099526. https://doi.org/10.1016/j.yebeh.2011.10.005

Desroches M, Burke J, Kaper TJ, Kramer MA. Canards of mixed type in a neural burster. Physical Review E—Statistical, Nonlinear, and Soft Matter Physics. 2012;85(2):021920. https://doi.org/10.1103/PhysRevE.85.021920

Burke J, Desroches M, Barry AM, Kaper TJ, Kramer MA. A showcase of torus canards in neuronal bursters. The Journal of Mathematical Neuroscience. 2012;2(1):3. https://doi.org/10.1186/2190-8567-2-3

Kramer MA, Truccolo W, Eden UT, Lepage KQ, Hochberg LR, Eskandar EN, Madsen JR, Lee JW, Maheshwari A, Halgren E, Chu CJ, Cash SS. Spontaneous seizure termination across spatial scales via a critical transition. Proc Natl Acad Sci USA. 2012;109(51):21116-21. https://doi.org/10.1073/pnas.1210047110

Chu CJ, Kramer MA, Pathmanathan J, Bianchi MT, Westover MB, Wizon L, Cash SS. Emergence of stable functional networks in long-term human EEG. J Neurosci. 2012;32(8):2703-13. https://doi.org/10.1523/JNEUROSCI.5669-11.2012

Kramer MA, Cash SS. Epilepsy as a disorder of cortical network organization. The Neuroscientist. 2012;18(4):360-72. https://doi.org/10.1177/1073858411422754

Lillis KP, Kramer MA, Mertz J, Staley KJ, White JA. Pyramidal cells accumulate chloride at seizure onset. Neurobiology of disease. 2012;47(3):358-66. https://doi.org/10.1016/j.nbd.2012.05.016

Ching S, Brown EN, Kramer MA. Distributed control in a mean-field cortical network model: implications for seizure suppression. Physical Review E—Statistical, Nonlinear, and Soft Matter Physics. 2012;86(2):021920. https://doi.org/10.1103/PhysRevE.86.021920

Kramer MA, Truccolo W, Eden UT, Lepage KQ, Hochberg LR, Eskandar EN, Madsen JR, Lee JW, Maheshwari A, Halgren E, Chu CJ. Human seizures self-terminate across spatial scales via a critical transition. Proceedings of the National Academy of Sciences. 2012;109(51):21116-21. https://doi.org/10.1073/pnas.1210047110

Numis AL, Yellen MB, Chu CJ, Pfeifer HH, Thiele EA. The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. Epilepsy Res. 2011;96(1-2):172-5. https://doi.org/10.1016/j.eplepsyres.2011.05.012

Kopell N, Whittington MA, Kramer MA. Neuronal assembly dynamics in the beta1 frequency range permits short-term memory. Proceedings of the National Academy of Sciences. 2011;108(9):3779-84. https://doi.org/10.1073/pnas.1019676108

Benes GN, Barry AM, Kaper TJ, Kramer MA, Burke J. An elementary model of torus canards. Chaos: An Interdisciplinary Journal of Nonlinear Science. 2011;21(2). https://doi.org/10.1063/1.3592798

Lepage KQ, Kramer MA, Eden UT. The dependence of spike field coherence on expected intensity. Neural computation. 2011;23(9):2209-41. https://doi.org/10.1162/NECO_a_00169

Kramer MA, Eden UT, Lepage KQ, Kolaczyk ED, Bianchi MT, Cash SS. Emergence of persistent networks in long-term intracranial EEG recordings. Journal of Neuroscience. 2011;31(44):15757-67. https://doi.org/10.1523/JNEUROSCI.2287-11.2011

Meng L, Kramer MA, Eden UT. A sequential Monte Carlo approach to estimate biophysical neural models from spikes. Journal of neural engineering. 2011;8(6):065006. https://doi.org/10.1088/1741-2560/8/6/065006

Tort AB, Fontanini A, Kramer MA, Jones-Lush LM, Kopell NJ, Katz DB. Cortical networks produce three distinct 7–12 Hz rhythms during single sensory responses in the awake rat. Journal of Neuroscience. 2010;30(12):4315-24. https://doi.org/10.1523/JNEUROSCI.6051-09.2010

Eden UT, Kramer MA. Drawing inferences from Fano factor calculations. Journal of neuroscience methods. 2010;190(1):149-52. https://doi.org/10.1016/j.jneumeth.2010.04.012

Kramer MA, Eden UT, Kolaczyk ED, Zepeda R, Eskandar EN, Cash SS. Coalescence and fragmentation of cortical networks during focal seizures. Journal of Neuroscience. 2010;30(30):10076-85. https://doi.org/10.1523/JNEUROSCI.6309-09.2010

Kopell N, Kramer MA, Malerba P, Whittington MA. Are different rhythms good for different functions?. Frontiers in human neuroscience. 2010;4:187. https://doi.org/10.3389/fnhum.2010.00187

Chu CJ and Thiele Ea. Tumor growth in patients with tuberous sclerosis complex on the ketogenic died. Brain and Development. 2010;32(4):318-22. (Case Series) https://doi.org/10.1016/j.braindev.2009.04.009

Chu CJ, Major P, Camposano S, Muzykewicz D, Thiele EA. The natural history of epilepsy in tuberous sclerosis complex. Epilepsia. 2010;51(7):1236-41. https://doi.org/10.1111/j.1528-1167.2009.02474.x

Xin W, Mullen TE, Kiely R, Min J, Feng X, Cao Y, O’Mally L, Shen Y, Chu, CJ, Mole SE, Goebel HH, Sims K. CLN5 mutations are surprisingly frequent in both juvenile and late-onset non-Finnish NCL patients. Neurology. 2010;74(7):565-71. PMID: 20157158. https://doi.org/10.1212/WNL.0b013e3181cff70d

Tort AB, Fontanini A, Kramer MA, Jones-Lush LM, Kopell NJ, Katz DB. Cortical networks produce three distinct 7–12 Hz rhythms during single sensory responses in the awake rat. Journal of Neuroscience. 2010;30(12):4315-24. https://doi.org/10.1523/JNEUROSCI.6051-09.2010

Eden UT, Kramer MA. Drawing inferences from Fano factor calculations. Journal of neuroscience methods. 2010;190(1):149-52. https://doi.org/10.1016/j.jneumeth.2010.04.012

Kramer MA, Eden UT, Kolaczyk ED, Zepeda R, Eskandar EN, Cash SS. Coalescence and fragmentation of cortical networks during focal seizures. Journal of Neuroscience. 2010;30(30):10076-85. https://doi.org/10.1523/JNEUROSCI.6309-09.2010

Kopell N, Kramer MA, Malerba P, Whittington MA. Are different rhythms good for different functions?. Frontiers in human neuroscience. 2010;4:187. https://doi.org/10.3389/fnhum.2010.00187

Chu CJ and Thiele Ea. Tumor growth in patients with tuberous sclerosis complex on the ketogenic died. Brain and Development. 2010;32(4):318-22. (Case Series) https://doi.org/10.1016/j.braindev.2009.04.009

Chu CJ, Major P, Camposano S, Muzykewicz D, Thiele EA. The natural history of epilepsy in tuberous sclerosis complex. Epilepsia. 2010;51(7):1236-41. https://doi.org/10.1111/j.1528-1167.2009.02474.x

Xin W, Mullen TE, Kiely R, Min J, Feng X, Cao Y, O’Mally L, Shen Y, Chu, CJ, Mole SE, Goebel HH, Sims K. CLN5 mutations are surprisingly frequent in both juvenile and late-onset non-Finnish NCL patients. Neurology. 2010;74(7):565-71. PMID: 20157158. https://doi.org/10.1212/WNL.0b013e3181cff70d

Tort AB, Kramer MA, Thorn C, Gibson DJ, Kubota Y, Graybiel AM, Kopell N J. Dynamic cross-frequency couplings of local field potential oscillations in rat striatum and hippocampus during performance of a T-maze task. Proceedings of the National Academy of Sciences. 2008;105(51):20517-20522. https://doi.org/10.1073/pnas.0810524105

Jones TA, Chu CJ, Grande LA, Gregory AD. Motor skills training enhances lesion-induced structural plasticity in the motor cortex of adult rats. J Neuroscience. 1999;19(22):10153-63. https://doi.org/10.1523/JNEUROSCI.19-22-10153.1999

Chu CJ, Jones TA. Experience-dependent structural plasticity in cortex heterotopic to focal sensorimotor cortical damage. Experemental Neurology. 2000;166(2):403-14. https://doi.org/10.1006/exnr.2000.7509