Lisa Kratz, Ph.D.

Lisa Kratz, Ph.D.'s picture
Director, Biochemical Genetics Laboratory

Kennedy Krieger Institute
707 N. Broadway
Baltimore, MD 21205
Phone: (443)923-2782

Dr. Lisa Kratz is the director of the Biochemical Genetics Laboratory at Kennedy Krieger Institute and an assistant professor in pediatrics at Johns Hopkins School of Medicine.

Biographical Sketch: 

Dr. Kratz received her Bachelor of Arts degree from Western Maryland College in 1985, and her doctorate in human genetics from the University of Maryland at Baltimore in 1989. She completed a post-doctoral fellowship in biochemical genetics at the University of Colorado Health Sciences Center in 1991, and was the assistant director of the Biochemical Diseases Detection Laboratory at Yale University from 1991 to 1993. Dr. Kratz was certified by the American Board of Medical Genetics and Genomics in biochemical genetics in 1993 and is a member of the Society For Inherited Metabolic Disorders (SIMD) and the Society for the Study of Inborn Errors of Metabolism (SSIEM). She has been with the Kennedy Krieger Institute since 1993. 

Research Summary: 

Dr. Kratz’s interests focus on the diagnosis of certain inborn errors of metabolism and clinical research related to these disorders. One area of interest involves disorders of cholesterol biosynthesis including Smith-Lemli-Opitz syndrome, Desmosterolosis, X-Linked Dominant Conradi Hünermann Syndrome, and SC4MOL deficiency. Other areas of interest include disorders of creatine synthesis and transport, Barth syndrome, and Mevalonate Kinase deficiency.

Research Publications:

Wassif CA, Kratz L, Sparks SE, Wheeler C, Bianconi S, Gropman A, Calis KA, Kelley RI, Tierney E, Porter FD (2016). A placebo-controlled trial of simvastatin therapy in Smith-Lemli-Opitz syndrome. Genet Med. , . Abstract
Gabitova L, Restifo D, Gorin A, Manocha K, Handorf E, Yang DH, Cai KQ, Klein-Szanto AJ, Cunningham D, Kratz LE, Herman GE, Golemis EA, Astsaturov I (2015). Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR. Cell Rep. 12(11), 1927-38. Abstract
Herman GE, Kratz L (2012). Disorders of sterol synthesis: beyond Smith-Lemli-Opitz syndrome. Am J Med Genet C Semin Med Genet. 160C(4), 301-21. Abstract

Other Publications:

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