Physical deconditioning is a process that affects all areas of the body after a long period of inactivity. This could include an inactive lifestyle or extended bedrest, especially after a severe injury or chronic disease. Physical deconditioning can affect patients of all ages and result in musculoskeletal system issues, including decreased muscle size and increased weakness. Some patients may also experience problems with their lungs, heart, and digestive tract.

In some cases, those with physical deconditioning may have a hard time completing tasks such as dressing themselves or sitting up in bed. Physical deconditioning may also cause psychological problems, such as depression and confusion.