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Bone Disorders Program

Kennedy Krieger Institute • 707 N. Broadway • Baltimore, MD 21205


Mahim Jain, MD, PhD

About Our Program:

Throughout our careers, we've watched as children and young adults with a range of injuries or disorders have overcome significant challenges during rehabilitation. The journey to regain abilities and function can be a slow one, and certain individuals seem to face more roadblocks than others. In some cases, their progress is slowed or stalled by underlying and sometimes overlooked bone related disorders that can result in painful fractures and other skeletal complications that inhibit recovery and care.

Too often, bone loss, low bone mass, or systemic bone disorders go unrecognized and undiagnosed, and rehabilitation efforts can seem to lose ground as quickly as it's gained. It was these types of situations that made it clear that a more comprehensive approach to disorders of the bone was necessary to provide a solid foundation for patient care. We are able to do this thanks to advances in the measurement of bone density and new therapeutic options.

Over the years, the Kennedy Krieger Institute has made important strides in treating Osteogenesis Imperfecta (OI), or brittle bone disease, and the OI Clinic at Kennedy Krieger Institute is recognized internationally as a major center for the treatment of this and related diseases. Our OI and bone specialists -- in accordance with the unique mission of the Institute -- also work as part of interdisciplinary teams treating children and young adults with a wide range of injuries and disorders of the brain and spinal cord.

Who We Serve:

Our program provides comprehensive support for a variety of complex medical and surgical issues involving acquired and inherited bone disorders including:

  • Idiopathic osteoporosis in children and young adults
  • Osteopenia due to cerebral palsy, spinal cord injury, immobilization, glucocorticoid use, or celiac disease
  • Unexplained frequent fracture syndromes
  • Mineral disorders such as Vitamin D deficiency, hypophosphatasia and hypophosphatemic syndromes
  • Genetic disorders such as Albright syndrome, fibrous dysplasia, osteogenesis imperfecta and Rett syndrome

Our Team:

Working as an interdisciplinary team, patient care is provided by the list of specialists below in the following fields:

  • Endocrinology
  • Orthopedics
  • Physical medicine and rehabilitation
  • Spinal cord injury
  • Nutrition
  • Pain management

Our Treatment Approach:

We are equipped with the latest technology, which allows us to offer a variety of diagnostic services, including:

  • Bone density measurements made by a DXA machine
  • Analysis of bone biomarkers (serum CTx, osteocalcin, bone specific alkaline phosphatase)
  • Complete bone density assessment
  • Genetic DNA analysis in collaboration with Matrix DNA Diagnostics at Tulane University in New Orleans, Louisiana

We also offer a variety of treatment options:

  • Nutritional modification
  • Swallowing function studies
  • Oral and intravenous bisphosphonates
  • Forteo, calcium, and vitamin supplementation

Schedule your initial appointment:

We welcome your questions and referrals. To schedule an appointment, for more information about a referral or evaluation, or to speak to someone by phone, please contact:

Care Management Office
Toll-free Referral: (888) 554-2080
Local Referral: (443) 923-9400

Change your appointment date/time or schedule a follow-up appointment:

To reschedule an appointment or to schedule a follow-up appointment, please call the Medical Care Center at (443) 923-2600.

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