Amy J. Bastian, Ph.D., P.T.

Dr. Amy Bastian
Amy Bastian
Chief Science Officer, Kennedy Krieger Institute; Director, Motion Analysis Laboratory

Kennedy Krieger Institute
707 N. Broadway
Baltimore, MD 21205
Phone: (443) 923-2716

Dr. Amy Bastian is the chief science officer at Kennedy Krieger Institute, a role in which she identifies and promotes new directions for breakthrough research into the developing brain, spinal cord, and musculoskeletal system. She is also director of the Motion Analysis Laboratory that studies the neural control of human movement. Dr. Bastian is a professor of neuroscience and neurology at the Johns Hopkins University School of Medicine.

Biographical Sketch:

After completing her undergraduate degree in physical therapy at the University of Oklahoma, Dr. Bastian completed her doctoral degree in movement science at Washington University in 1995, and a post-doctoral fellowship in neuroscience at Washington University under Dr. W.T. Thach. Dr. Bastian came to Kennedy Krieger Institute in Summer 2001. Prior to that, she was an assistant professor in physical therapy in the Department of Anatomy and Neurobiology at the Washington University School of Medicine in St. Louis.

Research Summary:

Dr. Bastian’s research uses computerized movement tracking techniques, non-invasive brain stimulation, novel devices and robotics to control walking and reaching movements. She studies how people with and without neurological damage control movement and learn new patterns. Some of her recent accomplishments include a series of papers on learning new walking patterns using a novel ‘split-belt’ treadmill published in the Journal of Neuroscience, Brain, and Nature Neuroscience. She has coauthored over 100 scientific papers and numerous book chapters and served as chair of the Musculoskeletal Rehabilitation Study Section at the National Institutes of Health (NIH). Dr. Bastian has given many named lectures, including a special lecture at the Society for Neuroscience meeting in 2014. She is currently the primary investigator on two R01 grants from the NIH, one of which recently received a prestigious Javits award from the National Institute of Neurological Disorders and Stroke (NINDS). Dr. Bastian has served on many national neuroscience and rehabilitation committees.

Dr. Bastian’s work has been featured in the mass media, including:

The Wall Street Journal: After a Stroke, Therapy Gets Faster
National Public Radio (NPR): Does the Fight for a Cursive Comeback Miss the Point?
USA Today: Odd Treadmill May Help Stroke Survivors

She has also appeared on the Emmy Award-nominated series on National Geographic called "Brain Games". The show explores topics related to the human brain and uses experts in cognitive science, neuroscience and psychology to explain various concepts.

LINK: SciVal Experts Research Profile for Amy Bastian

Research Publications:

Roemmich R.T., Bastian A.J. (2015). Two ways to save a newly learned motor patternJournal of Neurophysiology. doi: 10.1152/jn.00965.2014.

Long A.W., Finley J.M., Bastian A.J. (2015). A marching-walking hybrid induces step length adaptation and transfers to natural walkingJournal of Neurophysiology. doi: 10.1152/jn.00779.2014.

Therrien A.S., Bastian A.J. (2015). Cerebellar damage impairs internal predictions for sensory and motor functionCurrent Opinion in Neurobiology. doi: 10.1016/j.conb.2015.03.013.

Keller J.L., Bastian A.J. (2014). A home balance exercise program improves walking in people with cerebellar ataxiaNeurorehabilitation and Neural Repair, 28(8), 770-778.

Bhanpuri N.H., Okamura A.M., Bastian A.J. (2014). Predicting and correcting ataxia using a model of cerebellar functionBrain, 137(Pt 7), 1931-1944.

Musselman K.E., Stoyanov C.T., Marasigan R., Jenkins M.E., Konczak J., Morton S.M., Bastian A.J. (2014). Prevalence of ataxia in children: a systematic reviewNeurology, 82(1), 80-89.

Finley J.M., Bastian A.J., Gottschall J.S. (2013). Learning to be economical: the energy cost of walking tracks motor adaptation. The Journal of Physiology, 591(Pt 4), 1081-1095.

Reisman D.S., McLean H., Keller J., Danks K.A., Bastian A.J. (2013). Repeated Split-Belt Treadmill Training Improves Poststroke Step Length Asymmetry. Neurorehabilitation and Neural Repair, 27(5), 460-468.

Gibo T.L., Criscimagna-Hemminger S.E., Okamura A.M., Bastian A.J. (2013). Cerebellar motor learning: are environment dynamics more important than error size? Journal of Neurophysiology, 110(2), 322-333.

Bhanpuri N.H., Okamura A.M., Bastian A.J. (2013). Predictive modeling by the cerebellum improves proprioception. The Journal of Neuroscience, 33(36), 14301-14306.

Gibo T. L., Bastian A. J., Okamura A. M. (2013). Cerebellar ataxia impairs modulation of arm stiffness during postural maintenance. Journal of Neurophysiology, 110(7), 1611-1620.

Charles S. K., Okamura A. M., Bastian A. J. (2013). Does a basic deficit in force control underlie cerebellar ataxia? Journal of Neurophysiology, 109(4), 1107-16.

Hoyer E. H., Bastian A. J. (2013). The effects of task demands on bimanual skill acquisition. Experimental Brain Research, 226(2), 193-208.

Kurtzer I., Trautman P., Rasquinha R. J., Bhanpuri N. H., Scott S. H., Bastian A. J. (2013). Cerebellar damage diminishes long-latency responses to multijoint perturbations. Journal of Neurophysiology, 109(8), 2228-2241.

Fuentes C. T., Mostofsky S. H., Bastian A. J. (2011). No proprioceptive deficits in autism despite movement-related sensory and execution impairments. Journal of Autism and Developmental Disorders, 41(10), 1352-61.

Vasudevan E. V. L., Torres-Oviedo G., Morton S. M., Yang J. F., Bastian A. J. (2011). Younger is not always better: development of locomotor adaptation from childhood to adulthood. The Journal of Neuroscience, 31(8), 3055-65.

Jayaram G., Galea J. M., Bastian A. J., Celnik P. (2011). Human locomotor adaptive learning is proportional to depression of cerebellar excitability. Cerebral Cortex, 21(8), 1901-1909.

Fuentes, C. T., Mostofsky S. H., Bastian A. J. (2010). Perceptual reasoning predicts handwriting impairments in adolescents with autism. Neurology, 75(20), 1825-1829.

Block, H. J., Bastian A. J. (2010). Sensory reweighting in targeted reaching: effects of conscious effort, error history, and target salience. Journal of neurophysiology, 103(1), 206-217.

Fuentes, C. T., Bastian A. J. (2010). Where is your arm? Variations in proprioception across space and tasks. Journal of neurophysiology, 103(1), 164-71.

Vasudevan, E. V. L., Bastian A. J. (2010). Split-belt treadmill adaptation shows different functional networks for fast and slow human walking. Journal of Neurophysiology, 103(1), 183-191.

Torres-Oviedo G., Bastian A. J. (2010). Seeing is believing: effects of visual contextual cues on learning and transfer of locomotor adaptation. The Journal of Neuroscience, 30(50), 17015-17022.

Malone L. A., Bastian A. J. (2010). Thinking about walking: effects of conscious correction versus distraction on locomotor adaptation. Journal of Neurophysiology, 103(4), 1954-62.

Criscimagna-Hemminger S. E., Bastian A. J., Shadmehr R. (2010). Size of error affects cerebellar contributions to motor learning. Journal of Neurophysiology, 103(4), 2275-84.

Fuentes C. T., Mostofsky S. H., Bastian A. J. (2009). Children with autism show specific handwriting impairments. Neurology, 73(19), 1532-1537.

Zackowski K.M., Smith S.A., Reich D.S., Gordon-Lipkin E., Chodkowski B.A., Sambandan D.R., Shteyman M., Bastian A.J., Van Zijl P.C., Calabresi P.A. (2009). Sensorimotor dysfunction in multiple sclerosis and column-specific magnetization transfer-imaging abnormalities in the spinal cord. Brain: A Journal of Neurology, 132(Pt 5), 1200-1209.

Choi J. T., Vining E. P. G., Reisman D. S., Bastian A. J. (2009). Walking flexibility after hemispherectomy: split-belt treadmill adaptation and feedback control. Brain: A Journal of Neurology, 132(Pt 3), 722-733.

Kluzik J. A., Diedrichsen J., Shadmehr R., Bastian A. J. (2008). Reach adaptation: what determines whether we learn an internal model of the tool or adapt the model of our arm? Journal of Neurophysiology, 100(3), 1455-1464.

Bo J., Block H. J., Clark J. E., Bastian A. J. (2008). A cerebellar deficit in sensorimotor prediction explains movement timing variability. Journal of Neurophysiology, 100(5), 2825-2832.

Gidley Larson J. C., Bastian A. J., Donchin O., Shadmehr R., Mostofsky S. H. (2008). Acquisition of internal models of motor tasks in children with autism. Brain: A Journal of Neurology, 131(Pt 11), 2894-2903.

Thakur P. H., Bastian A. J., Hsiao S. S. (2008). Multidigit movement synergies of the human hand in an unconstrained haptic exploration task. The Journal of Neuroscience, 28(6), 1271-1281.

Bastian, A. J. (2008). Understanding sensorimotor adaptation and learning for rehabilitation. Current Opinion in Neurology, 21(6), 628-633.

Tseng Y.- W., Diedrichsen J., Krakauer J. W., Shadmehr R., Bastian A. J. (2007). Sensory prediction errors drive cerebellum-dependent adaptation of reaching. Journal of Neurophysiology, 98(1), 54-62.

Choi J. T., Bastian A. J. (2007). Adaptation reveals independent control networks for human walking. Nature Neuroscience, 10(8), 1055-1062.

Fuentes C. T., Bastian A. J. (2007). 'Motor cognition' - what is it and is the cerebellum involved? Cerebellum, 6(3), 232-236.

Zackowski K. M., Dubey P., Raymond G. V., Mori S., Bastian A. J., Moser H. W. (2006). Sensorimotor function and axonal integrity in adrenomyeloneuropathy. Archives of Neurology, 63(1), 74-80.

Bastian, A. J. (2006). Learning to predict the future: the cerebellum adapts feedforward movement control. Current Opinion in Neurobiology, 16(6), 645-649.

Gordon L. M., Keller J. L., Stashinko E. E., Hoon A. H., Bastian A. J. (2006). Can spasticity and dystonia be independently measured in cerebral palsy? Pediatric Neurology, 35(6), 375-381.