Kennedy Krieger Institute, 801 North Broadway, Baltimore, MD 21205

Participate in Research Studies

George Capone, M.D.

The mission of the Down Syndrome Clinic team is to help each individual with Down Syndrome reach his or her full potential and function as independently as possible in all aspects of family, school and community life. To this end, the clinic team provides initial and follow-up evaluations, preventive medical screening, medical consultation, parent-training and ongoing therapy.

Goals of Clinic:

The clinic strives to optimize the health and quality of life for children and adults with Down syndrome. As part of this goal, the clinic team continues to develop and conduct clinical research studies into the neurobiologic basis of cognitive impairment and co-morbid psychiatric disorders in Down syndrome; to study potential therapies for safety and efficacy; and to investigate genetic and environmental factors relevant to AV Canal defect.

Interesting trends over the last few years:

The Down Syndrome Clinic team continues to see children with complex neurobehavioral disorders (autistic-spectrum, self injury and aggressive/disruptive behaviors) as well as adults with mental health problems (depression, obsessive compulsive traits, motor slowing and functional decline). Several clinical research protocols are currently being used to study these issues in greater detail. The staff anticipates further development in this area of research as they seek to identify the neurobiologic basis for these disorders.

Research projects:

DS Mental Health:

• Down syndrome and autistic spectrum disorder
• Down syndrome and neuropsychiatric disorders

Development of Memory and Learning Skills
Usefulness of Computer-Based Testing to Measure Visual Memory and Movement

DS - Genetics of Congenital Heart Disease
DS Heart Project
Additional sites for DS Heart Project

DS - Clinical Trials:
Double-Blind Placebo-Controlled Study of FDA-Approved Drug, Rivastigmine

Down Syndrome Clinic: Every Tuesday, 8:30 a.m. - 4:00 p.m.

DS Research Evaluations: Wednesday and Thursday mornings by arrangement through DSC office.

Holly Center : - Salisbury, MD*

Washington Co Health Dept.: - Hagerstown, MD*

*The clinic meets at these satelite locations four times a year, by arrangement through CMO. This allows the clinic to serve more families and to accommodate those who are unable to travel to Baltimore.

To make a referral or request an initial evaluation:
Contact our Care Management Office
Toll-Free Referral: (888) 554-2080
Local Referral: (443) 923-9400

For follow-up appointments:
Lobby Care Center
Phone: (443) 923-3292

For Research:
Char Koller
(443) 923-9131
koller@kennedykrieger.org

·Down Syndrome
·Genetic Disorders

·Assistive Technology Clinic
·Audiology Clinic
·Behavioral Psychology Outpatient Programs
·Feeding Disorders Clinic
·Neurobehavioral Outpatient Clinic
·Neurology and Clinical Neurophysiology Clinic
·Neuropsychology and Developmental Psychology Clinic
·Occupational Therapy Clinic
·Orthopedic Outpatient Clinic
·Outpatient Psychiatry Clinic
·Physical Therapy Clinic
·Speech and Language Outpatient Clinic

·Center for Genetic Disorders of Cognition and Behavior
·Learning and Other Cognitive Disorders Research

The Resource Finder: A Project of Kennedy Krieger Institute

Kennedy Krieger Institute Down Syndrome Guide Articles

Additional Disability Solutions Articles

Disability Solutions Website
(http://www.diabilitysolutions.org)

Disability Solutions Down Syndrome / Autism Listserv
(http://groups.yahoo.com/group/ds-autism)

National Down Syndrome Society
(http://www.ndss.org)

National Down Syndrome Congress
(http://www.ndsccenter.org)

Down Syndrome: Health Issues
(http://www.ds-health.com)

Down Syndrome Association of the UK
(http://www.dsa-uk.com)

European Down Syndrome Association
(http://www.nas.com/downsyn/)

Down Syndrome Quarterly
(http://www.denison.edu/dsq/)


Outpatient Programs l Inpatient Programs l Community Programs l
Continuums l GeneticClinical Laboratories l Clinical Disciplines/Depts.