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Funded Research Projects

Biomarkers for Therapy of FSHD
Principal Investigator:
Wagner, Kathryn R.
The goal of this Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center is to define modifying genes of FSHD and to determine, through novel animal models of FSHD, whether these are...
Magnetic Resonance Spectroscopy Imaging as a Biomarker for FSHD
Principal Investigator:
Wagner, Kathryn R.
Sponsored by the American Academy of Neurology -- 2011 AAN Clinical Research Training Fellowship. Recent advances in the study of heritable neuromuscular disorders have led to multiple promising...
Acupressure and Acupuncture as an Intervention with Children with Autism II
Principal Investigator:
Warren, Lana
The purpose of this feasibility study is to see if children with autism spectrum disorder (ASD) will tolerate an acupressure and acupuncture intervention twice weekly over a 3 month period of time...
Acyl-CoA Synthetase ACSVL3 in Malignant Glioma: Metabolism and Oncogenic Cellular
Principal Investigator:
Watkins, Paul
Malignant glioma accounts for a significant percentage of brain tumors. As these tumors are typically refractory to treatment, there is a need for new and novel therapeutic approaches. Levels of...
Modeling Aggressive Medulloblastoma Using Human Induced Pluripotent Stem Cells
Principal Investigator:
Ying, Mingyao
Brain tumors are the most common cause of childhood oncological death, and medulloblastoma (MB) is the most common malignant pediatric brain tumor. Group 3 MB is characterized by amplification and...
Understanding Mechanisms of Lower Extremity Strengthening in Women Heterozygous for X-ALD
Principal Investigator:
Zackowski, Kathleen
Sponsored by the ELA Foundation. X-linked adrenoleukodystrophy (X-ALD), a sex-linked progressive neurodegenerative disease, is caused by a defect in the ABCD1 gene. The disease is expressed in...
Predicting Intervention Responsiveness to Improve Rehabilitation in People with Multiple Sclerosis
Principal Investigator:
Zackowski, Kathleen
Sponsored by the National Multiple Sclerosis Society -- RG 4668-A-1. Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) distinguished pathologically by...
Mechanisms of Locomotor Recovery in Multiple Sclerosis
Principal Investigator:
Zackowski, Kathleen
The study will test the general hypothesis that, in multiple sclerosis (MS) and following an acute exacerbation, damage of cerebellar white matter tracts (i.e. cerebellar peduncles) will show greater...

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