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Funded Research Projects
A Three Dimensional Environment for Skeletal Muscle Stem Cell Transplantation
Wagner, Kathryn R.
The purpose of this collaborative project is to develop and test and injectable scaffold embedded with muscle stem cells and a Pfizer drug to facilitate muscle regeneration. Cell based therapies...
Biomarkers for Therapy of FSHD
Wagner, Kathryn R.
The goal of this Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center is to define modifying genes of FSHD and to determine, through novel animal models of FSHD, whether these are...
Acupressure and Acupuncture as an Intervention with Children with Autism II
The purpose of this feasibility study is to see if children with autism spectrum disorder (ASD) will tolerate an acupressure and acupuncture intervention twice weekly over a 3 month period of time...
Acyl-CoA Synthetase ACSVL3 in Malignant Glioma: Metabolism and Oncogenic Cellular
Malignant glioma accounts for a significant percentage of brain tumors. As these tumors are typically refractory to treatment, there is a need for new and novel therapeutic approaches. Levels of...
Modeling Aggressive Medulloblastoma Using Human Induced Pluripotent Stem Cells
Brain tumors are the most common cause of childhood oncological death, and medulloblastoma (MB) is the most common malignant pediatric brain tumor. Group 3 MB is characterized by amplification and...
Mechanisms of Locomotor Recovery in Multiple Sclerosis
The study will test the general hypothesis that, in multiple sclerosis (MS) and following an acute exacerbation, damage of cerebellar white matter tracts (i.e. cerebellar peduncles) will show greater...
Understanding Mechanisms of Lower Extremity Strengthening in Women Heterozygous for X-ALD
Sponsored by the ELA Foundation. X-linked adrenoleukodystrophy (X-ALD), a sex-linked progressive neurodegenerative disease, is caused by a defect in the ABCD1 gene. The disease is expressed in...
Predicting Intervention Responsiveness to Improve Rehabilitation in People with Multiple Sclerosis
Sponsored by the National Multiple Sclerosis Society -- RG 4668-A-1. Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) distinguished pathologically by...
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