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Regulation of Glioblastoma Stem Cells by Kruppel-like Factors

Principal Investigator:

This research will examine mechanisms by which the family of Kruppel-like factors regulate the behavior, differentiation and tumor initiating ability of human GBM-derived stem cells.

We will obtain de-identified GBM-stem cells derived by Dr. Alfredo Quinones from discarded JHH pathological brain tumor specimens under approved IRB protocol #NA_00023842. These neoplastic stem cells will be used for experiments in vitro and to generate tumor xenografts for experimentation in vivo.

Kennedy Krieger Institute Announces Retirement of President and CEO

Dr. Gary W. GoldsteinThe Institute’s board of directors is conducting a national search and is expected to name a new CEO in the coming months.
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