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IDDRC Supported Projects

2017 IDDRC Projects and Supporting Cores

    B C D E F
Grant Number and Title Translational Genetics Neuroscience Neuroimaging Behavior
    3 1 10 36 15
Aggarwal, Manisha R21NS096249-01A1: Oscillating Gradient Diffusion MRI and Quantitative Susceptibility Mapping in the Epileptogenic Brain       X  
Blue, Mary/Kanna, Sujatha R21 NS100085: Dendrimer Therapies for Treatment of Rett Syndrome     X X  
Boger, Ravit R01 AI093701: Novel Artemisinin derivatives for cytomegalovirus therapy X       X
Burd, Irina K08 HD073315: IL-1β Regulation of Perinatal Brain Injury     X X  
Capone, George UL1-TR001079 (NBRU): Depression and Sleep Disorders in Adolescents and Young Adults with Down syndrome         X
Celnik, Pablo R01 HD053793: Novel Strategies to enhance motor function after stroke         X
Celnik, Pablo R01 HD073147: Understanding motor behavior after stroke          X
Celnik, Pablo UL1-TR001079 (NBRU): Effects of Excitation and Inhibition of the Temporo-Parietal Cortex via tDCS on Reading Performance in Children with Dyslexia         X
Cheng, Dominic K01 AA020873: Neuroimaging of Eyeblink Conditioning in Subjects with Alcohol Use Disorders       X  
Comi, Anne Cannabidiol expanded access study in medically refractory Sturge-Weber syndrome X        
Comi, Anne Trial of sirolimus for cognitive impairments in Sturge-Weber syndrome X        
Crawford, Thomas/Butchbach, Matthew E.R./Shaffer, Thomas Trial of sirolimus for cognitive impairments in Sturge-Weber syndrome   X      
Cutting, Gary R01 DK044003: Molecular genetics of cystic fibrosis: Creation and characterization of an airway epithelial cell line for stable expression of exogenous genes    X      
Dooley, Kelly R01 HD074944: Optimizing Treatment to Improve TBM Outcomes in Children: The TBM KIDS Trial         X
Edden, Richard R21 MH098228: Dysfunction of sensory
inhibition in Autism
      X X

Edden, Richard

R01MH106564: Somatosensory Inhibitory Dysfunction in Autism Spectrum Disorder       X  

Everett, Allen

R01 HD68446: GFAP Biomarker of Whole Body Cooling Outcome and Efficacy in the Neonate with HIE X     X  
Ewen, Joshua K23 NS073626: EEG-Based Assessment of Functional Connectivity in Autism         X
Ewen, Joshua R21 NS091569: Direct examination of
imitation based learning in Autism

Fatemi, S. Ali

K08 NS063956: Study of White Matter Development in a Rodent Model of Perinatal Brain Injury     X X  
Fatemi, S. Ali Brian’s Hope Foundation: Nanodendrimer-Based Targeted Delivery of the N-Acetylcysteine for Adrenoleukodystrophy: A Pilot Study to Determine Feasibility of Clinical Translation     X    

Findling, Robert

R01 MH073967: Longitudinal Assessment of Manic Symptoms  X     X  
Findling, Robert Software Treatment for Actively Reducing Severity of ADHD (STARS-ADHD) X        
Findling, Robert A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Molindone Hydrochloride Extended-Release Tablets for the Treatment of Impulsive Aggression in Pediatric Patients with Attention Deficit/Hyperactivity Disorder (ADHD) in Conjunction with Standard ADHD Treatment Objectives X       X
Findling, Robert Dasotraline Pediatric Extension Study X        
Findling, Robert Safety and Tolerability Study of SPD489 in Preschool Children Aged 4-5 Years, Diagnosed With Attention-deficit/Hyperactivity Disorder X        
Frazier, Jean R01 MH083320: A knowledge environment
for neuroimaging in child psychiatry
Germain-Lee, Emily R21 HD078864: The Role of G Protein-Coupled Signaling in Neurocognitive and Psychosocial Abnormalities         X
Hagopian, Louis R01 HD076653: Delineating subtypes of self-injurious behavior maintained by automatic reinforcement         X
Hardwick, JM R01 NS083373: Mechanisms of Neurodegeneration      X    
Hoon, Alexander UL1-TR001079 (NBRU): Interrelationships among quantitative measures of white matter injury, sensorimotor function and learning profiles in children with CP         X
Hoon, Alexander/Barker, Peter P41 RR015241 Sub-Project: Diffusion Tensor Imaging in Children with Cerebral Palsy         X
Hoover-Fong, Julie/Gunay-Aygun, Meral 03-HG-0264, NCT00068224: Clinical and Molecular Investigations into Ciliopathies   X      
Jacobson, Lisa PCORI Research Institute: Surviving Cancer, Thriving in Life: Health-related Quality of Life after Pediatric Cancer         X
Jacobson, Lisa R03 MH111965:  Defining the Sluggish Cognitive Tempo (SCT) Phenotype in Children         X
Johnston, Michael 2K12 NS001696: Neurology Sciences Academic Development Award (NSADA) X X     X
Jonas, Richard R01 HL104173: Protection of developing white matter during cardiac surgery      X X  
Kadam, Shilpa R21 HD073105: Neonatal Ischemic Seizures: Age and Gender Susceptibility to Refractoriness     X    
Kannan, Sujatha R01 HD069562: Mechanisms and Novel Therapy in Intrauterine Inflammation Induced Brain Injury     X X  
Kanna, Sujatha R01 NS093416: Targeting Glutamate Carboxypeptidase in Perinatal Brain Injury     X X  
Krinsky-McHale, Sharon/Silverman, Wayne P01 HD035897: Aging and Dementia in Adults with Down syndrome.  Subproject 2: (8402) Validation of Criteria for Identifying “MCI” in Adults with Down syndrome.  X       X
Landa, Rebecca R01 MH059630: Autism social and communication predictors in siblings X        
Landa, Rebecca R40 MC26193: Improving Part C Services and Outcomes for Underserved children with ASD X        
Laterra, John R01 NS076759: Suppression of Glioblastoma Stem Cells by Kruppel-Like Factor 9     X    
Laterra, John R01 NS096754: Chromatin Modifications in GBM-Propagating Cells     X X  
Lee, Gabsang R01 NS093213: Cell extrinsic factors’ roles on direct conversion to human induced neural crest   X      
Li, Rongfeng R35 GM 118172: Cellular Dynamics in Division, Motility, and Evolutionary Adaptation     X    
Lin, Doris UL1-TR001079 (NBRU): Noninvasive imaging and functional correlation of intracranial pial angiomatosis (SWS)       X  
Maegawa, Gustavo R01 NS079655: Development of an HTS assay for a neurological lysosomal disease    X      
Maegawa, Gustavo R21 NS071535: A HTS assay to identify molecular probes for arylsulfatase A      X    
Mahone, E. Mark R01 HD068425: Development of ADHD in Preschool Children: Neuroimaging and Behavioral Correlates        X X
Mahone, E. Mark UL1-TR001079 (NBRU): Neuroimaging of Motor Stereotypies in Children with and without Autism       X X
Mahone, E. Mark UL1-TR001079 (NBRU): DNA Methylation in Children with ADHD and/or Dyslexia         X
Mahone E. Mark Maryland State Department of Education (MSDE): Improving Equity in Access and Opportunity for Students with Disabilities         X
Mahone, E. Mark Maryland State Department of Education (MSDE):  School-Based Uses of Applied Behavior Analysis: Open Online Modules for Teachers, Administrators, and Special Education Student Support Staff         X
Meador, Kimford U01 NS038455: Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)         X
Miller, Michael R01 EB020062:  Neurogenerative and Neurodevelopmental Subcortical Shape Diffeomorphometry       X X
Moler, Frank U01 HL094345: Therapeutic Hypothermia After Pediatric Cardiac Arrest: A Randomized Controlled Trial (THAPCA)       X X
Mostofsky, Stewart UL1-TR001079 (NBRU): Tourette syndrome neuroimaging consortium pilot       X X
Mostofsky, Stewart R01 MH078160: 1/2 Anamalous Motor Physiology in ADHD       X X
Mostofsky, Stewart R01 MH085328: Adolescent Changes in Brain and Behavior in Boys and Girls with ADHD of deficient response control in ADHD       X X
Mostofsky, Stewart/Gilbert, Daniel R01 NS096207: GABAergic Sensorimotor Dysfunction in Tourette Syndrome       X X
Naidu, Sakkubai R01 FD004247: PH2 Study of dextromethorpan in the treatment of Rett syndrome X X X   X
Nebel, Mary Beth K01MH109766: Visual-Motor Development in Infants at High Risk for Autism       X  
Northington, Frances R01 HD070996: Mechanisms of hypothermic neuroprotection in neonates     X X  
Pelled, Galit R01 NS072171: The role of transcallosal pathway to neuroplasticity following nerve injury     X    
Pelled, Galit/Gilad, Assaf R01 NS079288: Adaptive control of epileptic seizures using a genetically encoded sensor     X X  
Pevsner, Jonathan U01 MH106884: Role of somatic mosaicism
in autism, schizophrenia and bipolar
disorder brain
Pritchard, Alison R03 EB023359: Role of Peripheral and Brain Iron in the Development of Attention and Cognitive Control       X X
Puts, Nicholaas K99 MH107719: A Multimodal Investigation of Inhibitory Dysfunction in Autism Spectrum Disorder       X  
Reeves, Roger R01 HD038384: Genomic Approaches to Aneuploidy     X    
Reinblatt, Shauna K23 MH083000: Pediatric Binge Eating, Impulsivity and Treatment         X
Robertson, Courtney 5U01NS081041-02: Approaches and Decisions in Acute Pediatric TBI (ADAPT)          
Rosch, Keri K23 MH101322: Delay discounting in Children with ADHD: Neuroimaging and Behavioral Correlates       X X
Scafidi, Susanna K08 NS069815: Metabolic dysfunction and neuroprotection after pediatric head injury      X    
Schupf, Nicole/Lott, Ira/Silverman, Wayne U01 AG051412: Biomarkers of Alzheimer’s disease in adults with Down syndrome X X   X X
Schupf, Nicole/Silverman, Wayne P01 HD035897: Aging and Dementia in Adults with Down syndrome. Subproject 4: (8404) Genetic Epidemiology of Alzheimer’s Disease in Down syndrome X        
Schwarz, Kathleen UL1-TR001079 (NBRU): A prospective database of infants with cholestasis         X
Schwarz, Kathleen UL1-TR001079 (NBRU): Biliary Artesia Research Consortium (BARC)         X
Seymour, Karen K23 MH107734:  Neurobehavioral correlates
of frustration in ADHD
      X X
Silverman, Wayne P01 HD035897: Aging and Dementia in Adults with Down syndrome         X
Singer, Harvey Tourette Association of America (TAA): Home-based Behavioral Intervention for Tics, Comparison of Home-based DVD Therapy and Psychologist-directed CBIT Treatment         X
Song, Xiaolei R21EB020905: In Vivo Molecular MR
Imaging of Inflammation Using NSAIDs as CEST
Suskauer, Stacy R21HD080378: Somatosensory processing-assessing youth sport-related concussion and recovery       X X
Suskauer, Stacy UL1-TR001079 (NBRU): Neural Basis of Impairments in Response Inhibition and Processing Speed         X
Tycko, Benjamin/Silverman, Wayne P01HD035897: Aging and dementia in adults with Down syndrome. Subproject 3: (8403) Epigenetic Modifiers in Down syndrome X        
Valle, David UM1 HG006542: Baylor-Johns Hopkins Center for Mendelian Genetics X X      
Vernon, Hilary K08HD073492: Metabolic studies in disorders of branch chain amino acid metabolism   X X    
Wagner, Kathryn U54 HD060848: Biomarkers for Therapy of FSHD     X    
Wagner, Kathryn Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of HT-100 in Duchenne Muscular Dystrophy X        
Wang, Tao R21NS085358: DHHC 15 palmitoylation modulates striatal dopamine system    X      
Watkins, Paul R21NS091988: Drug Discovery for X-Linked Adrenoleukodystrophy    X X    
Wilson, Mary Ann U54HD079123: IDDRC Research Component (6271): Multi-modal Treatment for Neonatal HIE: Hypothermia and Dendrimer Nanotherapy     X X X
Wu, Dan R21NS098018: In-Utero Characterization of Embryonic Mouse Brain Development and Injury with MRI       X  
Xia, Shuli R01NS091165: Methyl-CpG-Dependent Transcription Factor Function in Human Gliomas     X    
Yau, King-Wai R01EY014596: Melanopsin Photoreception and Signaling     X    
Zhang, Jiangyang R01HD074593: Imaging neonatal hypoxic ischemic injury       X  
Zhang, Jiangyanh R01NS070909: Mapping gene expression in the developing mouse brain       X  
Zhou, Jinyuan R21 EB015555: Molecular MRI of radiation necrosis in preclinical models     X