Necrostatin-1 inhibits the degeneration of neural cells induced by aluminum exposure.

TitleNecrostatin-1 inhibits the degeneration of neural cells induced by aluminum exposure.
Publication TypeJournal Article
Year of Publication2013
AuthorsQinli Z, Meiqing L, Xia J, Li X, Weili G, Xiuliang J, Junwei J, Hailan Y, Ce Z, Qiao N
JournalRestorative neurology and neuroscience
Volume31
Issue5
Pagination543-55
Date Published2013
Abstract

There are many in vivo and in vitro studies suggested the involvement of apoptosis in neurodegenerative processes. There is considerable evidence that various complex events may contribute to neural cell death. The present study focuses on the underlined neurodegenerative mechanism and the preventive effect of necrostatin-1 (Nec-1) on neural cell death induced by aluminum (Al).

DOI10.1099/ijs.0.056010-0
Alternate JournalRestor. Neurol. Neurosci.