Human brain white matter atlas: identification and assignment of common anatomical structures in superficial white matter.

Mark McIntosh,'s picture
PubMed URL: 
http://www.ncbi.nlm.nih.gov/pubmed/18692144
Author: 
Mori S
Author List: 
Oishi K
Zilles K
Amunts K
Faria A
Jiang H
Li X
Akhter K
Hua K
Woods R
Toga AW
Pike GB
Rosa-Neto P
Evans A
Zhang J
Huang H
Miller MI
van Zijl PC
Mazziotta J
Mori S
Journal: 
Neuroimage
PubMed ID: 
18692144
Pagination: 
447-57
Volume: 
43
Issue: 
3
Abstract: 
Structural delineation and assignment are the fundamental steps in understanding the anatomy of the human brain. The white matter has been structurally defined in the past only at its core regions (deep white matter). However, the most peripheral white matter areas, which are interleaved between the cortex and the deep white matter, have lacked clear anatomical definitions and parcellations. We used axonal fiber alignment information from diffusion tensor imaging (DTI) to delineate the peripheral white matter, and investigated its relationship with the cortex and the deep white matter. Using DTI data from 81 healthy subjects, we identified nine common, blade-like anatomical regions, which were further parcellated into 21 subregions based on the cortical anatomy. Four short association fiber tracts connecting adjacent gyri (U-fibers) were also identified reproducibly among the healthy population. We anticipate that this atlas will be useful resource for atlas-based white matter anatomical studies.
Published Date: 
November, 2008

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