Restoring function after spinal cord injury: promoting spontaneous regeneration with stem cells and activity-based therapies.

Mark McIntosh,'s picture
PubMed URL: 
http://www.ncbi.nlm.nih.gov/pubmed/17244561
Author: 
McDonald JW
Author List: 
Belegu V
Oudega M
Gary DS
McDonald JW
Journal: 
Neurosurg Clin N Am
PubMed ID: 
17244561
Pagination: 
143-68, xi
Volume: 
18
Issue: 
1
Abstract: 
Although neural regeneration is an active research field today, no current treatments can aid regeneration after spinal cord injury. This article reviews the feasibility of spinal cord repair and provides an overview of the range of strategies scientists are taking toward regeneration. The major focus of this article is the future role of stem cell transplantation and similar rehabilitative restorative approaches designed to optimize spontaneous regeneration by mobilizing endogenous stem cells and facilitating other cellular mechanisms of regeneration, such as axonal growth and myelination.
Published Date: 
January, 2007

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