Early characteristics of Sturge-Weber syndrome shown by perfusion MR imaging and proton MR spectroscopic imaging.

Mark McIntosh,'s picture
PubMed URL: 
http://www.ncbi.nlm.nih.gov/pubmed/14561628
Author: 
Comi A
Author List: 
Lin DD
Barker PB
Kraut MA
Comi A
Journal: 
AJNR Am J Neuroradiol
PubMed ID: 
14561628
Pagination: 
1912-5
Volume: 
24
Issue: 
9
Abstract: 
We report the case of a 9-month-old boy with Sturge-Weber syndrome and new onset of seizure. Perfusion MR imaging showed early changes compatible with impaired venous drainage in the affected hemisphere, whereas proton MR spectroscopic imaging revealed a focal parietal area of elevated choline without significant alteration of N-acetylaspartate levels. The perfusion and subtle metabolic abnormalities are comparable with the extent of the overlying leptomeningeal enhancement, illustrating the early pathophysiological manifestation of this disease.
Published Date: 
October, 2003

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