Research Frontiers

Research Frontiers: Trials of the Mind

Holly Lewis
Maddux
Kennedy Krieger Researchers Hope That Advancements in Alzheimer's Disease Will Address Early Memory Loss and Other Symptoms in Individuals with Down Syndrome

PrescriptionResearchers at Kennedy Krieger Institute are investigating two experimental treatments that it is hoped will slow or stop the progress of Alzheimer's disease in people with Down syndrome.

Research Frontiers: Mind Block

Courtney
McGrath
Study Probes Whether Drug Can Ease Neurological Decline Tied to Rett syndrome

Dr. SakkuBai NaiduSince the late Dr. Andreas Rett first identified the syndrome that bears his name more than 50 years ago, doctors have learned to treat the seizures, reflux and other symptoms of the disorder but they have not yet learned to alleviate the neurological impairment it causes. Researchers at Kennedy Krieger will begin a new drug trial this summer that represents an important step toward achieving that goal.

Research Frontiers: Communicating Milestones, When 2 Worry

Katherine
Holman
Kennedy Krieger Study Focuses on Following Children through the "Gray Period" of Language Development

Communication Milestones: When 2 WorryThe early years of a child's life are an exciting and promising time. Parents eagerly anticipate seeing their child's first steps and hearing her first words. But what happens when time passes and these milestones don't occur? When should parents seek help, and where can they find it?

Roots of A Dangerous Habit

Courtney
McGrath
New Study Investigates the Earliest Signs of Self-Injury in Children

Roots of a Dangerous HabitYoung children go through all sorts of phases, some of which can be alarming for parents. Tantrums, defiance, refusing to eat all can cause a great deal of stress. With time and patience, most of these habits fade quickly. A more disturbing problem for many families is self-injurious behavior like head banging, skin scratching or eye poking.

Research Frontiers: The Learning Curve

Anne
Hoffman
Kennedy Krieger awarded $9 million grant for Center for the Study of Reading Development.

Learning disabilities can be frustrating for the children who have them as well as for the parents trying to help. Not physically obvious, learning disabilities often create significant difficulties with academic and social skills when they are not properly identified or treated.

The Missing Link

Courtney
McGrath
Researcher Explores Connection Between Motor Learning Deficits and Communication and Socialization Impairments in Children with Autism

Dr. Stewart Mostofsky with ChildMost everyone knows the classic symptoms of autism: poor communication and difficulty interacting with others. Most treatment and research efforts focus on these deficits, but another area of concern is motor skill development.

Reading Between the Lines

Courtney
McGrath
In a First-of-Its-Kind Study, Researchers Will Learn Why So Many Adolescent Students Struggle to Read and How to Effectively Intervene.

The Importance of Effective Reading SkillsMost adults cannot recall exactly how they learned to read, or even remember a time when they couldn't. Reading is so integral to our lives that most of us take it for granted. It's fundamental to a quality education, essential to our jobs and an escape from mundane day-to-day rituals into worlds of adventure, glamour and intrigue.

The Study of Epigenetics

Martie
Callaghan

Are your genes turned on?

When scientists began The Human Genome Project in the early 1990s, their hope was to discover and interpret the entire blueprint for life, to decode not only how the human body is put together, but also to find the genetic cause and cure for every disease. Imagine their surprise when they discovered not the anticipated 100,000 genes, but rather 20,000 genes making up the human genome—about the same as that of fish and mice, and less than many plants!

Looking for an Alternative to Embryonic Stem Cells

Martie
Callaghan
Researchers hope that iPS cells may some day function as embryonic stem cells without the controversy

In 2009, the FDA approved the use of human embryonic stem cell-based therapy for the treatment of patients with spinal cord injuries. Cell-based therapy — the use of human cells transplanted into the human body to promote healing — is not a futuristic concept. Bone marrow transplant, for example, is a cell-based therapy that was proven to be safe and effective more than 50 years ago. Stem cells are particularly useful in these cell-based therapies because they are both immortal and flexible, meaning they can divide without end and they can become almost any type of cell.

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