Research Publications from 2012

Kennedy Krieger’s scientists and researchers are leaders in the worldwide effort to prevent and treat disorders of the brain, spinal cord, and musculoskeletal system. Learn about our innovative research initiatives and latest findings through our faculty research publications, Research Frontiers articles, and research press releases.

Airan, R. D., Bar-Shir A., Liu G., Pelled G., McMahon M. T., van Zijl P. C. M., et al. (2012). MRI biosensor for protein kinase A encoded by a single synthetic gene.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 68(6), 1919-23. Abstract

Whitcomb, D. C., Larusch J., Krasinskas A. M., Klei L., Smith J. P., Brand R. E., et al. (2012). Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.. Nature genetics. 44(12), 1349-54. Abstract

Lin, X. - F., Wang X. - D., Sun D. - Q., Li Z., & Bai Y. (2012). High Serum CEA and CYFRA21-1 Levels after a Two-Cycle Adjuvant Chemotherapy for NSCLC: Possible Poor Prognostic Factors.. Cancer biology & medicine. 9(4), 270-3. Abstract

Bhat, A. N., Galloway J. C., & Landa R. J. (2012). Relation between early motor delay and later communication delay in infants at risk for autism.. Infant behavior & development. 35(4), 838-46. Abstract

Pledger, M., McDonald J., & Cumming J. (2012). Increases in support structures for healthy eating especially in low decile schools in New Zealand.. Australian and New Zealand journal of public health. 36(6), 543-9. Abstract

Becker, D., Adhikary A., Tetteh S. T., Bull A. W., & Sevilla M. D. (2012). Kr-86 ion-beam irradiation of hydrated DNA: free radical and unaltered base yields.. Radiation research. 178(6), 524-37. Abstract

Ho, P. - L., Siu J. T. P., Law P. Y. T., Lai E. L., Tse C. W. S., Lee R., et al. (2012). Low prevalence of vancomycin heteroresistance among meticillin-resistant Staphylococcus aureus causing bacteraemia in Hong Kong.. International journal of antimicrobial agents. 40(6), 564-6.

Nics, L., Hahn A., Zeilinger M., Vraka C., Ungersboeck J., Haeusler D., et al. (2012). Quantification of the radio-metabolites of the serotonin-1A receptor radioligand [carbonyl-11C]WAY-100635 in human plasma: an HPLC-assay which enables measurement of two patients in parallel.. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 70(12), 2730-6. Abstract

Weekes, A. J., Reddy A., Lewis M. R., & Norton J. H. (2012). E-point septal separation compared to fractional shortening measurements of systolic function in emergency department patients: prospective randomized study.. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 31(12), 1891-7. Abstract

Herrera, D. G., Schiefelbein E. L., Smith R., Rojas R., Mirchandani G. G., & McDonald J. A. (2012). Cervical cancer screening in the US-Mexico border region: a binational analysis.. Maternal and child health journal. 16 Suppl 2, 298-306. Abstract

Paasch, V., Hoosier T. M., Accardo J., Ewen J. B., & Slifer K. J. (2012). Technical tips: performing EEGs and polysomnograms on children with neurodevelopmental disabilities.. The Neurodiagnostic journal. 52(4), 333-48. Abstract

Conceição, F., King M. A., Yeadon M. R., Lewis M. G. C., & Forrester S. E. (2012). An isovelocity dynamometer method to determine monoarticular and biarticular muscle parameters.. Journal of applied biomechanics. 28(6), 751-9. Abstract

Wu, F. - Y., Heng K. K., Salleh R. B., Soh T. G., Lee J. J., Mah J., et al. (2012). Comparing peripheral blood stem cell collection using the COBE Spectra, Haemonetics MCS+, and Baxter Amicus.. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 47(3), 345-50. Abstract

Low, C., Scheffer S. J., Lewis M. L., & Gates M. W. (2012). The relationship between variable host grouping and functional responses among parasitoids of Antispila nysaefoliella (Lepidoptera: Heliozelidae).. Molecular ecology. 21(23), 5892-904. Abstract

Unschuld, P. G., Joel S. E., Pekar J. J., Reading S. A., Oishi K., McEntee J., et al. (2012). Depressive symptoms in prodromal Huntington's Disease correlate with Stroop-interference related functional connectivity in the ventromedial prefrontal cortex.. Psychiatry research. 203(2-3), 166-74. Abstract

Lu, H., & van Zijl P. C. M. (2012). A review of the development of Vascular-Space-Occupancy (VASO) fMRI.. NeuroImage. 62(2), 736-42. Abstract

van Zijl, P. C. M., Hua J., & Lu H. (2012). The BOLD post-stimulus undershoot, one of the most debated issues in fMRI.. NeuroImage. 62(2), 1092-102. Abstract

Li, X., Vikram D. S., Lim I. A. L., Jones C. K., Farrell J. A. D., & van Zijl P. C. M. (2012). Mapping magnetic susceptibility anisotropies of white matter in vivo in the human brain at 7 T.. NeuroImage. 62(1), 314-30. Abstract

Hornillos, V., van Zijl A. W., & Feringa B. L. (2012). Catalytic asymmetric synthesis of chromenes and tetrahydroquinolines via sequential allylic alkylation and intramolecular Heck coupling.. Chemical communications (Cambridge, England). 48(31), 3712-4. Abstract

Unschuld, P. G., Joel S. E., Liu X., Shanahan M., Margolis R. L., Biglan K. M., et al. (2012). Impaired cortico-striatal functional connectivity in prodromal Huntington's Disease.. Neuroscience letters. 514(2), 204-9. Abstract

Hess, C. R., & Landa R. J. (2012). Predictive and concurrent validity of parent concern about young children at risk for autism.. Journal of autism and developmental disorders. 42(4), 575-84. Abstract

Lin, C. - Y., Yadav N. N., Friedman J. I., Ratnakar J., Sherry D. A., & van Zijl P. C. M. (2012). Using frequency-labeled exchange transfer to separate out conventional magnetization transfer effects from exchange transfer effects when detecting ParaCEST agents.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 67(4), 906-11. Abstract

Liu, G., Moake M., Har-el Y. -el, Long C. M., Chan K. W. Y., Cardona A., et al. (2012). In vivo multicolor molecular MR imaging using diamagnetic chemical exchange saturation transfer liposomes.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 67(4), 1106-13. Abstract

Liao, Z., Duan X. - D., Xin L., Bo L. - M., Wang X. - H., Xiao G. - H., et al. (2012). Feasibility and safety of magnetic-controlled capsule endoscopy system in examination of human stomach: a pilot study in healthy volunteers.. Journal of interventional gastroenterology. 2(4), 155-160. Abstract

Arora, G., Mezencev R., & McDonald J. F. (2012). Human cells display reduced apoptotic function relative to chimpanzee cells.. PloS one. 7(9), e46182. Abstract

Pollard, B., Johnston M., & Dixon D. (2012). Exploring differential item functioning in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).. BMC musculoskeletal disorders. 13, 265. Abstract

Phillips, A. W., Falahati S., Desilva R., Shats I., Marx J., Arauz E., et al. (2012). Derivation of glial restricted precursors from E13 mice.. Journal of visualized experiments : JoVE. Abstract

Yap, J. L., Wachtel L. E., Ahn E. S., Sanz J. H., Slomine B. S., & Pidcock F. S. (2012). Treatment of cerebellar cognitive affective syndrome with aripiprazole.. Journal of pediatric rehabilitation medicine. 5(3), 233-8. Abstract

Gipson, T. T., & Johnston M. V. (2012). Plasticity and mTOR: towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disorders.. Neural plasticity. 2012, 486402. Abstract

Thibert, K. A., Raymond G. V., Nascene D. R., Miller W. P., Tolar J., Orchard P. J., et al. (2012). Cerebrospinal fluid matrix metalloproteinases are elevated in cerebral adrenoleukodystrophy and correlate with MRI severity and neurologic dysfunction.. PloS one. 7(11), e50430. Abstract

Mezencev, R., Wang L., & McDonald J. F. (2012). Identification of inhibitors of ovarian cancer stem-like cells by high-throughput screening.. Journal of ovarian research. 5(1), 30. Abstract

Becker, D., Willems L. M., Vnencak M., Zahn N., Schuldt G., Jedlicka P., et al. (2012). Functional and structural properties of dentate granule cells with hilar basal dendrites in mouse entorhino-hippocampal slice cultures.. PloS one. 7(11), e48500. Abstract

Eccles, M. P., Grimshaw J. M., Maclennan G., Bonetti D., Glidewell L., Pitts N. B., et al. (2012). Explaining clinical behaviors using multiple theoretical models.. Implementation science : IS. 7, 99. Abstract

McDonald, J. P., Vaisman A., Kuban W., Goodman M. F., & Woodgate R. (2012). Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol V.. PLoS genetics. 8(11), e1003030. Abstract

McDonald, J. W., Tsoulis D. J., Macdonald J. K., & Feagan B. G. (2012). Methotrexate for induction of remission in refractory Crohn's disease.. Cochrane database of systematic reviews (Online). 12, CD003459. Abstract

Elbers, C. C., Guo Y., Tragante V., van Iperen E. P. A., Lanktree M. B., Castillo B. A., et al. (2012). Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.. PloS one. 7(12), e50198. Abstract

Wagner, K. D., Moynihan M. J., Strathdee S. A., Cuevas-Mota J., Clark M., Zúñiga M. L., et al. (2012). The social and environmental context of cross-border drug use in Mexico: findings from a mixed methods study of young injection drug users living in San Diego, CA.. Journal of ethnicity in substance abuse. 11(4), 362-78. Abstract

Fischer, A. H., Becker D., & Veenstra L. (2012). Emotional mimicry in social context: the case of disgust and pride.. Frontiers in psychology. 3, 475. Abstract

Tan, J., Lim P. - E., Phang S. - M., Hong D. D., Sunarpi H., & Hurtado A. Q. (2012). Assessment of four molecular markers as potential DNA barcodes for red algae Kappaphycus Doty and Eucheuma J. Agardh (Solieriaceae, Rhodophyta).. PloS one. 7(12), e52905. Abstract

Furberg, R. D., Uhrig J. D., Bann C. M., Lewis M. A., Harris J. L., Williams P., et al. (2012). Technical Implementation of a Multi-Component, Text Message-Based Intervention for Persons Living with HIV.. JMIR research protocols. 1(2), e17. Abstract

Zumaya-Estrada, F. A., Messenger L. A., Lopez-Ordonez T., Lewis M. D., Flores-Lopez C. A., Martínez-Ibarra A. J., et al. (2012). North American import? Charting the origins of an enigmatic Trypanosoma cruzi domestic genotype.. Parasites & vectors. 5, 226. Abstract

Ibana, J. A., Myers L., Porretta C., Lewis M., Taylor S. N., Martin D. H., et al. (2012). The major CD8 T cell effector memory subset in the normal and Chlamydia trachomatis-infected human endocervix is low in perforin.. BMC immunology. 13, 66. Abstract

Xu, W., Mezencev R., Kim B., Wang L., McDonald J., & Sulchek T. (2012). Cell stiffness is a biomarker of the metastatic potential of ovarian cancer cells.. PloS one. 7(10), e46609. Abstract

Cataldo, M. J., Bonini-Domingos A. C., & Bonini-Domingos C. R. (2012). Heterozygosis for hemoglobin Porto Alegre identified by a combination of laboratory diagnostic methodologies.. Revista brasileira de hematologia e hemoterapia. 34(4), 305-6.

McDonald, J. U., Rosas M., Brown G. D., Jones S. A., & Taylor P. R. (2012). Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation.. PloS one. 7(9), e45781. Abstract

Bhattacharya, C., Wang X., & Becker D. (2012). The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas.. Molecular cancer. 11, 82. Abstract

Li, S., Eloyan A., Joel S., Mostofsky S., Pekar J., Bassett S. S., et al. (2012). Analysis of group ICA-based connectivity measures from fMRI: application to Alzheimer's disease.. PloS one. 7(11), e49340. Abstract

Ho, J., Barbi de Moura M., Lin Y., Vincent G., Thorne S., Duncan L. M., et al. (2012). Importance of glycolysis and oxidative phosphorylation in advanced melanoma.. Molecular cancer. 11, 76. Abstract

Chen, D. T., Shepherd L., & Becker D. M. (2012). The HPV vaccine and parental consent.. The virtual mentor : VM. 14(1), 5-12.

Lewis, M. A., & Hobday T. J. (2012). Treatment of neuroendocrine tumor liver metastases.. International journal of hepatology. 2012, 973946. Abstract

Sadler, N. C., Angel T. E., Lewis M. P., Pederson L. M., Chauvigné-Hines L. M., Wiedner S. D., et al. (2012). Activity-based protein profiling reveals mitochondrial oxidative enzyme impairment and restoration in diet-induced obese mice.. PloS one. 7(10), e47996. Abstract

Astobiza, I., Tilburg J. J., Piñero A., Hurtado A., García-Pérez A. L., Nabuurs-Franssen M. H., et al. (2012). Genotyping of Coxiella burnetii from domestic ruminants in northern Spain.. BMC veterinary research. 8, 241. Abstract

Deib, G., Poretti A., Meoded A., Cohen K. J., Raymond G. V., Abromowitch M., et al. (2012). Onset of adreno-leukodystrophy after medulloblastoma therapy: causal connection or coincidence?. JIMD reports. 2, 29-32. Abstract

Inoue, J., Wada J., Teshigawara S., Hida K., Nakatsuka A., Takatori Y., et al. (2012). The serum vaspin levels are reduced in Japanese chronic hemodialysis patients.. BMC nephrology. 13, 163. Abstract

Szkutnik-Fiedler, D., Kus K., Balcerkiewicz M., Grześkowiak E., Nowakowska E., Burda K., et al. (2012). Concomitant use of tramadol and venlafaxine - evaluation of antidepressant-like activity and other behavioral effects in rats.. Pharmacological reports : PR. 64(6), 1350-8. Abstract

Rachagani, S., Torres M. P., Kumar S., Haridas D., Baine M., Macha M. A., et al. (2012). Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy.. Journal of hematology & oncology. 5, 68. Abstract

Chau, D., Becker D., Coombes M., Ioannidis G., Adachi J., & Goeree R. (2012). Cost-effectiveness of denosumab in the treatment of postmenopausal osteoporosis in Canada.. Journal of medical economics. 15 Suppl 1, 3-14. Abstract

Fair, D. A., Nigg J. T., Iyer S., Bathula D., Mills K. L., Dosenbach N. U. F., et al. (2012). Distinct neural signatures detected for ADHD subtypes after controlling for micro-movements in resting state functional connectivity MRI data.. Frontiers in systems neuroscience. 6, 80. Abstract

Docherty, C. J., Lin C. - T., Joyce H. J., Nicholas R. J., Herz L. M., Li L. - J., et al. (2012). Extreme sensitivity of graphene photoconductivity to environmental gases.. Nature communications. 3, 1228. Abstract

Smith, S. A., Pekar J. J., & van Zijl P. C. M. (2012). Advanced MRI strategies for assessing spinal cord injury.. Handbook of clinical neurology. 109, 85-101. Abstract

Franzén, O., Talavera-López C., Ochaya S., Butler C. E., Messenger L. A., Lewis M. D., et al. (2012). Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei.. BMC genomics. 13, 531. Abstract

McDonald, J. W., Sadowsky C. L., & Stampas A. (2012). The changing field of rehabilitation: optimizing spontaneous regeneration and functional recovery.. Handbook of clinical neurology. 109, 317-36. Abstract

Gallun, F. J., Diedesch A. C., Kubli L. R., Walden T. C., Folmer R. L., Lewis S. M., et al. (2012). Performance on tests of central auditory processing by individuals exposed to high-intensity blasts.. Journal of rehabilitation research and development. 49(7), 1005-25. Abstract

Becker, D., & McDonald J. W. (2012). Approaches to repairing the damaged spinal cord: overview.. Handbook of clinical neurology. 109, 445-61. Abstract

Gallun, F. J., Lewis S. M., Folmer R. L., Diedesch A. C., Kubli L. R., McDermott D. J., et al. (2012). Implications of blast exposure for central auditory function: a review.. Journal of rehabilitation research and development. 49(7), 1059-74. Abstract

Suktitipat, B., Mathias R. A., Vaidya D., Yanek L. R., Young H. J., Becker L. C., et al. (2012). The robustness of generalized estimating equations for association tests in extended family data.. Human heredity. 74(1), 17-26. Abstract

Verhaagen, J., & McDonald J. W. (2012). Preface.. Handbook of clinical neurology. 109, ix.

Stevens, E. L., Baugher J. D., Shirley M. D., Frelin L. P., & Pevsner J. (2012). Unexpected relationships and inbreeding in HapMap phase III populations.. PloS one. 7(11), e49575. Abstract

Switzeny, O. J., Müllner E., Wagner K. - H., Brath H., Aumüller E., & Haslberger A. G. (2012). Vitamin and antioxidant rich diet increases MLH1 promoter DNA methylation in DMT2 subjects.. Clinical epigenetics. 4(1), 19.

Figueroa-Romero, C., Hur J., Bender D. E., Delaney C. E., Cataldo M. D., Smith A. L., et al. (2012). Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis.. PloS one. 7(12), e52672. Abstract

Newschaffer, C. J., Croen L. A., Fallin D. M., Hertz-Picciotto I., Nguyen D. V., Lee N. L., et al. (2012). Infant siblings and the investigation of autism risk factors.. Journal of neurodevelopmental disorders. 4(1), 7. Abstract

Alhasan, M. K., Liu L., Lewis M. A., Magnusson J., & Mason R. P. (2012). Comparison of optical and power Doppler ultrasound imaging for non-invasive evaluation of arsenic trioxide as a vascular disrupting agent in tumors.. PloS one. 7(9), e46106. Abstract