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Research Publications from 2006

Kennedy Krieger’s scientists and researchers are leaders in the worldwide effort to prevent and treat disorders of the brain, spinal cord, and musculoskeletal system. Learn about our innovative research initiatives and latest findings through our faculty research publications, Research Frontiers articles, and research press releases.

Shindle, M. K., Khanna J. A., Bhatnagar R., & Sponseller P. D. (2006).  Adolescent idiopathic scoliosis: modern management guidelines.. Journal of surgical orthopaedic advances. 15(1), 43-52. Abstract
Hubbard, W. C., Moser A. B., Tortorelli S., Liu A., Jones D., & Moser H. (2006).  Combined liquid chromatography-tandem mass spectrometry as an analytical method for high throughput screening for X-linked adrenoleukodystrophy and other peroxisomal disorders: preliminary findings.. Molecular genetics and metabolism. 89(1-2), 185-7. Abstract
Leet, A. I., Mesfin A., Pichard C., Launay F., Brintzenhofeszoc K., Levey E. B., et al. (2006).  Fractures in children with cerebral palsy.. Journal of pediatric orthopedics. 26(5), 624-7. Abstract
Mori, S., & Zhang J. (2006).  Principles of diffusion tensor imaging and its applications to basic neuroscience research.. Neuron. 51(5), 527-39. Abstract
Tierney, E., Bukelis I., Thompson R. E., Ahmed K., Aneja A., Kratz L., et al. (2006).  Abnormalities of cholesterol metabolism in autism spectrum disorders.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 141B(6), 666-8. Abstract
Budimirovic, D. B., Bukelis I., Cox C., Gray R. M., Tierney E., & Kaufmann W. E. (2006).  Autism spectrum disorder in Fragile X syndrome: differential contribution of adaptive socialization and social withdrawal.. American journal of medical genetics. Part A. 140A(17), 1814-26. Abstract
Davis, L. M., Pei Z., Trush M. A., Cheskin L. J., Contoreggi C., McCullough K., et al. (2006).  Bromocriptine reduces steatosis in obese rodent models.. Journal of hepatology. 45(3), 439-44. Abstract
Singer, H. S., Morris C. M., Williams P. N., Yoon D. Y., Hong J. J., & Zimmerman A. W. (2006).  Antibrain antibodies in children with autism and their unaffected siblings.. Journal of neuroimmunology. 178(1-2), 149-55. Abstract
Jansen, J. F. A., Shamblott M. J., van Zijl P. C. M., Lehtimäki K. K., Bulte J. W. M., Gearhart J. D., et al. (2006).  Stem cell profiling by nuclear magnetic resonance spectroscopy.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 56(3), 666-70. Abstract
Jones, C. K., Schlosser M. J., van Zijl P. C. M., Pomper M. G., Golay X., & Zhou J. (2006).  Amide proton transfer imaging of human brain tumors at 3T.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 56(3), 585-92. Abstract
Aksentijevich, I., Jones R. J., Ambinder R. F., Garrett-Mayer E., & Flinn I. W. (2006).  Clinical outcome following autologous and allogeneic blood and marrow transplantation for relapsed diffuse large-cell non-Hodgkin's lymphoma.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 12(9), 965-72. Abstract
Keefer, J. R., Schneidereith T. A., Mays A., Purvis S. H., Dover G. J., & Smith K. D. (2006).  Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.. Experimental hematology. 34(9), 1151-61. Abstract
Connors, S. L., Matteson K. J., Sega G. A., Lozzio C. B., Carroll R. C., & Zimmerman A. W. (2006).  Plasma serotonin in autism.. Pediatric neurology. 35(3), 182-6. Abstract
Buchowski, J. M., Bhatnagar R., Skaggs D. L., & Sponseller P. D. (2006).  Temporary internal distraction as an aid to correction of severe scoliosis.. The Journal of bone and joint surgery. American volume. 88(9), 2035-41. Abstract
Mahone, M. E., Powell S. K., Loftis C. W., Goldberg M. C., Denckla M. B., & Mostofsky S. H. (2006).  Motor persistence and inhibition in autism and ADHD.. Journal of the International Neuropsychological Society : JINS. 12(5), 622-31. Abstract
Rijnierse, A., van Zijl K. M. F., Koster A. S., Nijkamp F. P., & Kraneveld A. D. (2006).  Beneficial effect of tachykinin NK1 receptor antagonism in the development of hapten-induced colitis in mice.. European journal of pharmacology. 548(1-3), 150-7. Abstract
Huang, H., Zhang J., Wakana S., Zhang W., Ren T., Richards L. J., et al. (2006).  White and gray matter development in human fetal, newborn and pediatric brains.. NeuroImage. 33(1), 27-38. Abstract
Mazzocco, M. M. M. (2006).  The cognitive phenotype of Turner syndrome: Specific learning disabilities.. International congress series / Excerpta Medica. 1298, 83-92. Abstract
Khalifeh, M. R., & Redett R. J. (2006).  The management of patients on anticoagulants prior to cutaneous surgery: case report of a thromboembolic complication, review of the literature, and evidence-based recommendations.. Plastic and reconstructive surgery. 118(5), 110e-117e.
dosReis, S., Butz A., Lipkin P. H., Anixt J. S., Weiner C. L., & Chernoff R. (2006).  Attitudes about stimulant medication for attention-deficit/hyperactivity disorder among African American families in an inner city community.. The journal of behavioral health services & research. 33(4), 423-30. Abstract
Smith, S. A., Farrell J. A. D., Jones C. K., Reich D. S., Calabresi P. A., & van Zijl P. C. M. (2006).  Pulsed magnetization transfer imaging with body coil transmission at 3 Tesla: feasibility and application.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 56(4), 866-75. Abstract
Reich, D. S., Smith S. A., Jones C. K., Zackowski K. M., van Zijl P. C., Calabresi P. A., et al. (2006).  Quantitative characterization of the corticospinal tract at 3T.. AJNR. American journal of neuroradiology. 27(10), 2168-78. Abstract
Kuhn, D. E., DeLeon I. G., Terlonge C., & Goysovich R. (2006).  Comparison of verbal preference assessments in the presence and absence of the actual stimuli.. Research in developmental disabilities. 27(6), 645-56. Abstract
Ladasky, J. J., Boyle S., Seth M., Li H., Pentcheva T., Abe F., et al. (2006).  Bap31 enhances the endoplasmic reticulum export and quality control of human class I MHC molecules.. Journal of immunology (Baltimore, Md. : 1950). 177(9), 6172-81. Abstract
Mathews, R., Gearhart J. P., Bhatnagar R., & Sponseller P. (2006).  Staged pelvic closure of extreme pubic diastasis in the exstrophy-epispadias complex.. The Journal of urology. 176(5), 2196-8. Abstract
Lee, L. - C., Zachary A. A., Leffell M. S., Newschaffer C. J., Matteson K. J., Tyler J. D., et al. (2006).  HLA-DR4 in families with autism.. Pediatric neurology. 35(5), 303-7. Abstract
Leet, A. I., Sampath J. S., Scott C. I., & MacKenzie W. G. (2006).  Cervical spinal stenosis in metatropic dysplasia.. Journal of pediatric orthopedics. 26(3), 347-52. Abstract
Ain, M. C., Shirley E. D., Pirouzmanesh A., Skolasky R. L., & Leet A. I. (2006).  Genu varum in achondroplasia.. Journal of pediatric orthopedics. 26(3), 375-9. Abstract
Mostofsky, S. H., Dubey P., Jerath V. K., Jansiewicz E. M., Goldberg M. C., & Denckla M. B. (2006).  Developmental dyspraxia is not limited to imitation in children with autism spectrum disorders.. Journal of the International Neuropsychological Society : JINS. 12(3), 314-26. Abstract
Barreiro, C. J., Williams J. A., Fitton T. P., Lange M. S., Blue M. E., Kratz L., et al. (2006).  Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest using magnetic resonance spectroscopy.. The Annals of thoracic surgery. 81(5), 1593-8. Abstract
Pekar, J. J. (2006).  A brief introduction to functional MRI.. IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society. 25(2), 24-6.
McDonald, J. W., & Belegu V. (2006).  Demyelination and remyelination after spinal cord injury.. Journal of neurotrauma. 23(3-4), 345-59. Abstract
Pei, Z., Jia Z., & Watkins P. A. (2006).  The second member of the human and murine bubblegum family is a testis- and brainstem-specific acyl-CoA synthetase.. The Journal of biological chemistry. 281(10), 6632-41. Abstract
Farasat, S., Kossoff E. H., Pillas D. J., Rubenstein J. E., Vining E. P., & Freeman J. M. (2006).  The importance of parental expectations of cognitive improvement for their children with epilepsy prior to starting the ketogenic diet.. Epilepsy & behavior : E&B. 8(2), 406-10. Abstract
Levine, T. M., Materek A., Abel J., O'Donnell M., & Cutting L. E. (2006).  Cognitive profile of neurofibromatosis type 1.. Seminars in pediatric neurology. 13(1), 8-20. Abstract
Sponseller, P. D., Jones K. B., Ahn N. U., Erkula G., Foran J. R. H., & Dietz H. C. (2006).  Protrusio acetabuli in Marfan syndrome: age-related prevalence and associated hip function.. The Journal of bone and joint surgery. American volume. 88(3), 486-95. Abstract
McCarthy, M. L., MacKenzie E. J., Durbin D. R., Aitken M. E., Jaffe K. M., Paidas C. N., et al. (2006).  Health-related quality of life during the first year after traumatic brain injury.. Archives of pediatrics & adolescent medicine. 160(3), 252-60. Abstract
Slifer, K. J., Pulbrook V., Amari A., Vona-Messersmith N., Cohn J. F., Ambadar Z., et al. (2006).  Social acceptance and facial behavior in children with oral clefts.. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. 43(2), 226-36. Abstract
Trovato, M., Slomine B., Pidcock F., & Christensen J. (2006).  The efficacy of donepezil hydrochloride on memory functioning in three adolescents with severe traumatic brain injury.. Brain injury : [BI]. 20(3), 339-43. Abstract
Vasa, R. A., Carlino A. R., & Pine D. S. (2006).  Pharmacotherapy of depressed children and adolescents: current issues and potential directions.. Biological psychiatry. 59(11), 1021-8. Abstract
Grados, M. A., & Walkup J. T. (2006).  A new gene for Tourette's syndrome: a window into causal mechanisms?. Trends in genetics : TIG. 22(6), 291-3. Abstract
Landa, R., & Garrett-Mayer E. (2006).  Development in infants with autism spectrum disorders: a prospective study.. Journal of child psychology and psychiatry, and allied disciplines. 47(6), 629-38. Abstract
Williams, J. A., Barreiro C. J., Nwakanma L. U., Lange M. S., Kratz L. E., Blue M. E., et al. (2006).  Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery.. The Annals of thoracic surgery. 81(6), 2235-41; discussion 2241-2. Abstract
Mahone, M. E., Wodka E. L., & Hiemenz J. R. (2006).  Hand and eye preference and their association with task approach by preschoolers.. Perceptual and motor skills. 102(3), 691-702. Abstract
Russell, J. C., Szuflita N., Khatri R., Laterra J., & Hossain M. A. (2006).  Transgenic expression of human FGF-1 protects against hypoxic-ischemic injury in perinatal brain by intervening at caspase-XIAP signaling cascades.. Neurobiology of disease. 22(3), 677-90. Abstract
Huff, C. A., Matsui W. H., Smith D. B., & Jones R. J. (2006).  Strategies to eliminate cancer stem cells: clinical implications.. European journal of cancer (Oxford, England : 1990). 42(9), 1293-7. Abstract
Cao, Y., Miller M. I., Mori S., Winslow R. L., & Younes L. (2006).  Diffeomorphic Matching of Diffusion Tensor Images.. Proceedings / CVPR, IEEE Computer Society Conference on Computer Vision and Pattern Recognition. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. 2006, 67. Abstract
Mazzocco, M. M. M., & Myers G. F. (2006).  Maximizing Efficiency of Enrollment for School-Based Educational Research.. Journal of applied social psychology. 32(8), 1577-1587. Abstract
Murphy, M. M., Mazzocco M. M. M., Gerner G., & Henry A. E. (2006).  Mathematics learning disability in girls with Turner syndrome or fragile X syndrome.. Brain and cognition. 61(2), 195-210. Abstract
Jansiewicz, E. M., Goldberg M. C., Newschaffer C. J., Denckla M. B., Landa R., & Mostofsky S. H. (2006).  Motor signs distinguish children with high functioning autism and Asperger's syndrome from controls.. Journal of autism and developmental disorders. 36(5), 613-21. Abstract
Huff, C. A., Matsui W., Smith D. B., & Jones R. J. (2006).  The paradox of response and survival in cancer therapeutics.. Blood. 107(2), 431-4. Abstract
Wang, Y., Zhang J., Mori S., & Nathans J. (2006).  Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(2), 355-64. Abstract
Mostofsky, S. H., Rimrodt S. L., Schafer J. G. B., Boyce A., Goldberg M. C., Pekar J. J., et al. (2006).  Atypical motor and sensory cortex activation in attention-deficit/hyperactivity disorder: a functional magnetic resonance imaging study of simple sequential finger tapping.. Biological psychiatry. 59(1), 48-56. Abstract
Lachance, J. A., & Mazzocco M. M. M. (2006).  A longitudinal analysis of sex differences in math and spatial skills in primary school age children.. Learning and individual differences. 16(3), 195-216. Abstract
Cox, C. S., Dubey P., Raymond G. V., Mahmood A., Moser A. B., & Moser H. W. (2006).  Cognitive evaluation of neurologically asymptomatic boys with X-linked adrenoleukodystrophy.. Archives of neurology. 63(1), 69-73. Abstract
Zackowski, K. M., Dubey P., Raymond G. V., Mori S., Bastian A. J., & Moser H. W. (2006).  Sensorimotor function and axonal integrity in adrenomyeloneuropathy.. Archives of neurology. 63(1), 74-80. Abstract
Zhang, J., van Zijl P. C. M., & Mori S. (2006).  Image contrast using the secondary and tertiary eigenvectors in diffusion tensor imaging.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 55(2), 439-49. Abstract
Jiang, H., van Zijl P. C. M., Kim J., Pearlson G. D., & Mori S. (2006).  DtiStudio: resource program for diffusion tensor computation and fiber bundle tracking.. Computer methods and programs in biomedicine. 81(2), 106-16. Abstract
Kossoff, E. H., McGrogan J. R., Bluml R. M., Pillas D. J., Rubenstein J. E., & Vining E. P. (2006).  A modified Atkins diet is effective for the treatment of intractable pediatric epilepsy.. Epilepsia. 47(2), 421-4. Abstract
Marsh, E. B., Freeman J. M., Kossoff E. H., Vining E. P. G., Rubenstein J. E., Pyzik P. L., et al. (2006).  The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year.. Epilepsia. 47(2), 425-30. Abstract
Poling, J. S., Frye R. E., Shoffner J., & Zimmerman A. W. (2006).  Developmental regression and mitochondrial dysfunction in a child with autism.. Journal of child neurology. 21(2), 170-2. Abstract
Steinberg, S. J., Dodt G., Raymond G. V., Braverman N. E., Moser A. B., & Moser H. W. (2006).  Peroxisome biogenesis disorders.. Biochimica et biophysica acta. 1763(12), 1733-48. Abstract
Bastian, A. J. (2006).  Learning to predict the future: the cerebellum adapts feedforward movement control.. Current opinion in neurobiology. 16(6), 645-9. Abstract
Donahue, M. J., Lu H., Jones C. K., Edden R. A. E., Pekar J. J., & van Zijl P. C. M. (2006).  Theoretical and experimental investigation of the VASO contrast mechanism.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 56(6), 1261-73. Abstract
Gordon, L. M., Keller J. L., Stashinko E. E., Hoon A. H., & Bastian A. J. (2006).  Can spasticity and dystonia be independently measured in cerebral palsy?. Pediatric neurology. 35(6), 375-81. Abstract
Wang, W. - Q., Li R., Bai Q. - X., Liu Y. - H., Zhang W. - P., Wang J. - H., et al. (2006).  Gossypol-Induced Differentiation in Human Leukemia HL-60 Cells.. International journal of biomedical science : IJBS. 2(4), 395-401. Abstract
Donahue, M. J., Lu H., Jones C. K., Pekar J. J., & van Zijl P. C. M. (2006).  An account of the discrepancy between MRI and PET cerebral blood flow measures. A high-field MRI investigation.. NMR in biomedicine. 19(8), 1043-54. Abstract
Loeys, B. L., Schwarze U., Holm T., Callewaert B. L., Thomas G. H., Pannu H., et al. (2006).  Aneurysm syndromes caused by mutations in the TGF-beta receptor.. The New England journal of medicine. 355(8), 788-98. Abstract
Comi, A. M., Highet B. H., Mehta P., Hana Chong T., Johnston M. V., & Wilson M. A. (2006).  Dextromethorphan protects male but not female mice with brain ischemia.. Neuroreport. 17(12), 1319-22. Abstract
Denckla, M. B. (2006).  Attention-deficit hyperactivity disorder (ADHD) comorbidity: a case for "pure" Tourette syndrome?. Journal of child neurology. 21(8), 701-3. Abstract
Lin, D. D. M., Barker P. B., Hatfield L. A., & Comi A. M. (2006).  Dynamic MR perfusion and proton MR spectroscopic imaging in Sturge-Weber syndrome: correlation with neurological symptoms.. Journal of magnetic resonance imaging : JMRI. 24(2), 274-81. Abstract
Darbari, A., Kalloo A. N., & Cuffari C. (2006).  Diagnostic yield, safety, and efficacy of push enteroscopy in pediatrics.. Gastrointestinal endoscopy. 64(2), 224-8. Abstract
Mazzocco, M. M. M., Thompson L., Sudhalter V., Belser R. C., Lesniak-Karpiak K., & Ross J. L. (2006).  Language use in females with fragile X or Turner syndrome during brief initial social interactions.. Journal of developmental and behavioral pediatrics : JDBP. 27(4), 319-28. Abstract
Halbower, A. C., Degaonkar M., Barker P. B., Earley C. J., Marcus C. L., Smith P. L., et al. (2006).  Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury.. PLoS medicine. 3(8), e301. Abstract
Samuels, J. F., Riddle M. A., Greenberg B. D., Fyer A. J., McCracken J. T., Rauch S. L., et al. (2006).  The OCD collaborative genetics study: methods and sample description.. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 141B(3), 201-7. Abstract
Mazzocco, M. M. M., Singh Bhatia N., & Lesniak-Karpiak K. (2006).  Visuospatial skills and their association with math performance in girls with fragile X or Turner syndrome.. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. 12(2), 87-110. Abstract
Halbower, A. C., & Mahone M. E. (2006).  Neuropsychological morbidity linked to childhood sleep-disordered breathing.. Sleep medicine reviews. 10(2), 97-107. Abstract
McMahon, M. T., Gilad A. A., Zhou J., Sun P. Z., Bulte J. W. M., & van Zijl P. C. M. (2006).  Quantifying exchange rates in chemical exchange saturation transfer agents using the saturation time and saturation power dependencies of the magnetization transfer effect on the magnetic resonance imaging signal (QUEST and QUESP): Ph calibration for poly. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 55(4), 836-47. Abstract
Slomine, B. S., McCarthy M. L., Ding R., MacKenzie E. J., Jaffe K. M., Aitken M. E., et al. (2006).  Health care utilization and needs after pediatric traumatic brain injury.. Pediatrics. 117(4), e663-74. Abstract
Comi, A. M. (2006).  Advances in Sturge-Weber syndrome.. Current opinion in neurology. 19(2), 124-8. Abstract
Huff, C. A., Fuchs E. J., Smith D. B., Blackford A., Garrett-Mayer E., Brodsky R. A., et al. (2006).  Graft-versus-host reactions and the effectiveness of donor lymphocyte infusions.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 12(4), 414-21. Abstract
Gao, F., Qiu B., Kar S., Zhan X., Hofmann L. V., & Yang X. (2006).  Intravascular magnetic resonance/radiofrequency may enhance gene therapy for prevention of in-stent neointimal hyperplasia.. Academic radiology. 13(4), 526-30. Abstract
Moser, H. W. (2006).  Therapy of X-linked adrenoleukodystrophy.. NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics. 3(2), 246-53. Abstract
Parsons, G. N., Siberry G. K., Parsons K. J., Christensen J. R., Joyner M. L., Lee S. L., et al. (2006).  Multidisciplinary, inpatient directly observed therapy for HIV-1-infected children and adolescents failing HAART: A retrospective study.. AIDS patient care and STDs. 20(4), 275-84. Abstract
Johnston, M. V., & Hoon A. H. (2006).  Cerebral palsy.. Neuromolecular medicine. 8(4), 435-50. Abstract
Ting, J. C., Ye Y., Thomas G. H., Ruczinski I., & Pevsner J. (2006).  Analysis and visualization of chromosomal abnormalities in SNP data with SNPscan.. BMC bioinformatics. 7, 25. Abstract
Mori, S., Zhang J., & Bulte J. W. M. (2006).  Magnetic resonance microscopy of mouse brain development.. Methods in molecular medicine. 124, 129-47. Abstract
Kerr, C. L., Shamblott M. J., & Gearhart J. D. (2006).  Pluripotent stem cells from germ cells.. Methods in enzymology. 419, 400-26. Abstract
Wachtel, L. E., & Hagopian L. P. (2006).  Psychopharmacology and applied behavioral analysis: tandem treatment of severe problem behaviors in intellectual disability and a case series.. The Israel journal of psychiatry and related sciences. 43(4), 265-74. Abstract
Zhang, J., Richards L. J., Miller M. I., Yarowsky P., van Zijl P., & Mori S. (2006).  Characterization of mouse brain and its development using diffusion tensor imaging and computational techniques.. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 1, 2252-5. Abstract

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