Research Publications from 2003

Kennedy Krieger’s scientists and researchers are leaders in the worldwide effort to prevent and treat disorders of the brain, spinal cord, and musculoskeletal system. Learn about our innovative research initiatives and latest findings through our faculty research publications, Research Frontiers articles, and research press releases.

Kurtz, P. F., Chin M. D., Huete J. M., Tarbox R. S. F., O'Connor J. T., Paclawskyj T. R., et al. (2003). Functional analysis and treatment of self-injurious behavior in young children a summary of 30 cases.. Journal of applied behavior analysis. 36(2), 205-19. Abstract

Lipkin, P. H., Butz A. M., & Cozen M. A. (2003). High-dose methylphenidate treatment of attention deficit hyperactivity disorder in a preschooler.. Journal of child and adolescent psychopharmacology. 13(1), 103-6. Abstract

DeLeon, I. G., Arnold K. L., Rodriguez-Catter V., & Uy M. L. (2003). Covariation between bizarre and nonbizarre speech as a function of the content of verbal attention.. Journal of applied behavior analysis. 36(1), 101-4. Abstract

Dawson, J. E., Piazza C. C., Sevin B. M., Gulotta C. S., Lerman D., & Kelley M. L. (2003). Use of the high-probability instructional sequence and escape extinction in a child with food refusal.. Journal of applied behavior analysis. 36(1), 105-8. Abstract

DeLeon, I. G., Kahng S. W., Rodriguez-Catter V., Sveinsdóttir I., & Sadler C. (2003). Assessment of aberrant behavior maintained by wheelchair movement in a child with developmental disabilities.. Research in developmental disabilities. 24(5), 381-90. Abstract

Luo, H. R., Hattori H., Hossain M. A., Hester L., Huang Y., Lee-Kwon W., et al. (2003). Akt as a mediator of cell death.. Proceedings of the National Academy of Sciences of the United States of America. 100(20), 11712-7. Abstract

Matsushita, H., Johnston M. V., Lange M. S., & Wilson M. A. (2003). Protective effect of erythropoietin in neonatal hypoxic ischemia in mice.. Neuroreport. 14(13), 1757-61. Abstract

Hansel, D. E., Hansel C. R. W., Shindle M. K., Reinhardt E. M., Madden L. V., Levey E. B., et al. (2003). Oral baclofen in cerebral palsy: possible seizure potentiation?. Pediatric neurology. 29(3), 203-6. Abstract

Denckla, M. B. (2003). ADHD: topic update.. Brain & development. 25(6), 383-9.

Darbari, A., Sabin K. M., Shapiro C. N., & Schwarz K. B. (2003). Epidemiology of primary hepatic malignancies in U.S. children.. Hepatology (Baltimore, Md.). 38(3), 560-6. Abstract

Hoon, A. H., Belsito K. M., & Nagae-Poetscher L. M. (2003). Neuroimaging in spasticity and movement disorders.. Journal of child neurology. 18 Suppl 1, S25-39. Abstract

Pizzini, F., Fatemi A. S., Barker P. B., Nagae-Poetscher L. M., Horská A., Zimmerman A. W., et al. (2003). Proton MR spectroscopic imaging in Pelizaeus-Merzbacher disease.. AJNR. American journal of neuroradiology. 24(8), 1683-9. Abstract

Bastian, A. J., Kelly V. E., Revilla F. J., Perlmutter J. S., & Mink J. W. (2003). Different effects of unilateral versus bilateral subthalamic nucleus stimulation on walking and reaching in Parkinson's disease.. Movement disorders : official journal of the Movement Disorder Society. 18(9), 1000-7. Abstract

Bastian, A. J., Kelly V. E., Perlmutter J. S., & Mink J. W. (2003). Effects of pallidotomy and levodopa on walking and reaching movements in Parkinson's disease.. Movement disorders : official journal of the Movement Disorder Society. 18(9), 1008-17. Abstract

Kefalov, V., Fu Y., Marsh-Armstrong N., & Yau K. - W. (2003). Role of visual pigment properties in rod and cone phototransduction.. Nature. 425(6957), 526-31. Abstract

Matsushita, K., Morrell C. N., Cambien B., Yang S. X., Yamakuchi M., Bao C., et al. (2003). Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.. Cell. 115(2), 139-50. Abstract

Naidu, S., Bibat G., Kratz L., Kelley R. I., Pevsner J., Hoffman E., et al. (2003). Clinical variability in Rett syndrome.. Journal of child neurology. 18(10), 662-8. Abstract

Jarrar, M. H., Danko C. G., Reddy S., Lee Y. - J. M., Bibat G., & Kaufmann W. E. (2003). MeCP2 expression in human cerebral cortex and lymphoid cells: immunochemical characterization of a novel higher-molecular-weight form.. Journal of child neurology. 18(10), 675-82. Abstract

Johnston, M. V., Mullaney B., & Blue M. E. (2003). Neurobiology of Rett syndrome.. Journal of child neurology. 18(10), 688-92. Abstract

Peri, S., Navarro D. J., Amanchy R., Kristiansen T. Z., Jonnalagadda C. K., Surendranath V., et al. (2003). Development of human protein reference database as an initial platform for approaching systems biology in humans.. Genome research. 13(10), 2363-71. Abstract

Lin, D. D. M., Barker P. B., Kraut M. A., & Comi A. (2003). Early characteristics of Sturge-Weber syndrome shown by perfusion MR imaging and proton MR spectroscopic imaging.. AJNR. American journal of neuroradiology. 24(9), 1912-5. Abstract

Slifer, K. J., Diver T., Amari A., Cohn J. F., Hilley L., Beck M., et al. (2003). Assessment of facial emotion encoding and decoding skills in children with and without oral clefts.. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 31(5), 304-15. Abstract

Pei, Z., Oey N. A., Zuidervaart M. M., Jia Z., Li Y., Steinberg S. J., et al. (2003). The acyl-CoA synthetase "bubblegum" (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation... The Journal of biological chemistry. 278(47), 47070-8. Abstract

Johnston, M. V. (2003). Injury and plasticity in the developing brain.. Experimental neurology. 184 Suppl 1, S37-41.

Zhang, J., Richards L. J., Yarowsky P., Huang H., van Zijl P. C. M., & Mori S. (2003). Three-dimensional anatomical characterization of the developing mouse brain by diffusion tensor microimaging.. NeuroImage. 20(3), 1639-48. Abstract

Grados, M. A. (2003). Obsessive-compulsive disorder after traumatic brain injury.. International review of psychiatry (Abingdon, England). 15(4), 350-8. Abstract

Lancelotta, M. P., Sheth R. N., Meyer R. A., Belzberg A. J., Griffin J. W., & Campbell J. N. (2003). Severity and duration of hyperalgesia in rat varies with type of nerve lesion.. Neurosurgery. 53(5), 1200-8; discussion 1208-9. Abstract

Cutting, L. E., Koth C. W., Mahone M. E., & Denckla M. B. (2003). Evidence for unexpected weaknesses in learning in children with attention-deficit/hyperactivity disorder without reading disabilities.. Journal of learning disabilities. 36(3), 259-69. Abstract

Heinzer, A. K., Watkins P. A., Lu J. - F., Kemp S., Moser A. B., Li Y., et al. (2003). A very long-chain acyl-CoA synthetase-deficient mouse and its relevance to X-linked adrenoleukodystrophy.. Human molecular genetics. 12(10), 1145-54. Abstract

Comi, A. M., Hunt P., Vawter M. P., Pardo C. A., Becker K. G., & Pevsner J. (2003). Increased fibronectin expression in sturge-weber syndrome fibroblasts and brain tissue.. Pediatric research. 53(5), 762-9. Abstract

Oguz, K. K., Golay X., Pizzini F. B., Freer C. A., Winrow N., Ichord R., et al. (2003). Sickle cell disease: continuous arterial spin-labeling perfusion MR imaging in children.. Radiology. 227(2), 567-74. Abstract

Mao, R., Zielke C. L., Zielke R. H., & Pevsner J. (2003). Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain.. Genomics. 81(5), 457-67. Abstract

Pillion, J. P., Rawool V. W., Bibat G., & Naidu S. (2003). Prevalence of hearing loss in Rett syndrome.. Developmental medicine and child neurology. 45(5), 338-43. Abstract

Huff, C. A., Fuchs E. J., Noga S. J., O'Donnell P. V., Ambinder R. F., Diehl L., et al. (2003). Long-term follow-up of T cell-depleted allogeneic bone marrow transplantation in refractory multiple myeloma: importance of allogeneic T cells.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 9(5), 312-9. Abstract

Johnston, M. V. (2003). MRI for neonatal encephalopathy in full-term infants.. Lancet. 361(9359), 713-4.

van Zijl, P. C. M., Zhou J., Mori N., Payen J. - F., Wilson D., & Mori S. (2003). Mechanism of magnetization transfer during on-resonance water saturation. A new approach to detect mobile proteins, peptides, and lipids.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 49(3), 440-9. Abstract

Johnston, M. V., Alemi L., & Harum K. H. (2003). Learning, memory, and transcription factors.. Pediatric research. 53(3), 369-74. Abstract

Kerr, D. A., Lladó J., Shamblott M. J., Maragakis N. J., Irani D. N., Crawford T. O., et al. (2003). Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(12), 5131-40. Abstract

Pulsifer, M. B., Salorio C. F., & Niparko J. K. (2003). Developmental, audiological, and speech perception functioning in children after cochlear implant surgery.. Archives of pediatrics & adolescent medicine. 157(6), 552-8. Abstract

Hagelthorn, K. M., Hiemenz J. R., Pillion J. P., & Mahone M. E. (2003). Age and task parameters in continuous performance tests for preschoolers.. Perceptual and motor skills. 96(3 Pt 1), 975-89. Abstract

Kwiterovich, P. O., Chen S. C., Virgil D. G., Schweitzer A., Arnold D. R., & Kratz L. E. (2003). Response of obligate heterozygotes for phytosterolemia to a low-fat diet and to a plant sterol ester dietary challenge.. Journal of lipid research. 44(6), 1143-55. Abstract

Snoussi, K., Bulte J. W. M., Guéron M., & van Zijl P. C. M. (2003). Sensitive CEST agents based on nucleic acid imino proton exchange: detection of poly(rU) and of a dendrimer-poly(rU) model for nucleic acid delivery and pharmacology.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 49(6), 998-1005. Abstract

Yu, X., Zhan X., D'Costa J., Tanavde V. M., Ye Z., Peng T., et al. (2003). Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells.. Molecular therapy : the journal of the American Society of Gene Therapy. 7(6), 827-38. Abstract

Banks, N. D., Redett R. J., Mofid M. Z., & Manson P. N. (2003). Cutis laxa: clinical experience and outcomes.. Plastic and reconstructive surgery. 111(7), 2434-42; discussion 2443-4.

Mears, S., Schachner M., & Brushart T. M. (2003). Antibodies to myelin-associated glycoprotein accelerate preferential motor reinnervation.. Journal of the peripheral nervous system : JPNS. 8(2), 91-9. Abstract

Okubadejo, G. O., Sponseller P. D., & Gearhart J. P. (2003). Complications in orthopedic management of exstrophy.. Journal of pediatric orthopedics. 23(4), 522-8. Abstract

Khanna, J. A., Wasserman B. A., & Sponseller P. D. (2003). Magnetic resonance imaging of the pediatric spine.. The Journal of the American Academy of Orthopaedic Surgeons. 11(4), 248-59. Abstract

Mostofsky, S. H., Schafer J. G. B., Abrams M. T., Goldberg M. C., Flower A. A., Boyce A., et al. (2003). fMRI evidence that the neural basis of response inhibition is task-dependent.. Brain research. Cognitive brain research. 17(2), 419-30. Abstract

Kaufmann, W. E., Cooper K. L., Mostofsky S. H., Capone G. T., Kates W. R., Newschaffer C. J., et al. (2003). Specificity of cerebellar vermian abnormalities in autism: a quantitative magnetic resonance imaging study.. Journal of child neurology. 18(7), 463-70. Abstract

Teshima, Y., Akao M., Li R. A., Chong T. H., Baumgartner W. A., Johnston M. V., et al. (2003). Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress.. Stroke; a journal of cerebral circulation. 34(7), 1796-802. Abstract

Mazzocco, M. M. M., & Myers G. F. (2003). Complexities in Identifying and Defining Mathematics Learning Disability in the Primary School-Age Years.. Annals of dyslexia. 53(1), 218-253. Abstract

Drachman, D. B., Jones R. J., & Brodsky R. A. (2003). Treatment of refractory myasthenia: "rebooting" with high-dose cyclophosphamide.. Annals of neurology. 53(1), 29-34. Abstract

Phelps, J. Y., Bugg E. M., Shamblott M. J., Vlahos N. P., Whelan J., & Zacur H. A. (2003). Prolactin gene expression in human ovarian follicular cells.. Fertility and sterility. 79(1), 182-5. Abstract

Petri, M., Jones R. J., & Brodsky R. A. (2003). High-dose cyclophosphamide without stem cell transplantation in systemic lupus erythematosus.. Arthritis and rheumatism. 48(1), 166-73. Abstract

Comi, A. M., Fischer R., & Kossoff E. H. (2003). Encephalofacial angiomatosis sparing the occipital lobe and without facial nevus: on the spectrum of Sturge-Weber syndrome variants?. Journal of child neurology. 18(1), 35-8. Abstract

Li, Z., Yang S., Lin H., Huang J., Watkins P. A., Moser A. B., et al. (2003). Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease.. Hepatology (Baltimore, Md.). 37(2), 343-50. Abstract

Lesniak-Karpiak, K., Mazzocco M. M. M., & Ross J. L. (2003). Behavioral assessment of social anxiety in females with Turner or fragile X syndrome.. Journal of autism and developmental disorders. 33(1), 55-67. Abstract

Koontz, K. L., Slifer K. J., Cataldo M. D., & Marcus C. L. (2003). Improving pediatric compliance with positive airway pressure therapy: the impact of behavioral intervention.. Sleep. 26(8), 1010-5. Abstract

Zhou, J., Lal B., Wilson D. A., Laterra J., & van Zijl P. C. M. (2003). Amide proton transfer (APT) contrast for imaging of brain tumors.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 50(6), 1120-6. Abstract

Grados, M. A., Walkup J., & Walford S. (2003). Genetics of obsessive-compulsive disorders: new findings and challenges.. Brain & development. 25 Suppl 1, S55-61. Abstract

Mostofsky, S. H., Newschaffer C. J., & Denckla M. B. (2003). Overflow movements predict impaired response inhibition in children with ADHD.. Perceptual and motor skills. 97(3 Pt 2), 1315-31. Abstract

Ha, P. K., Benoit N. E., Yochem R., Sciubba J., Zahurak M., Sidransky D., et al. (2003). A transcriptional progression model for head and neck cancer.. Clinical cancer research : an official journal of the American Association for Cancer Research. 9(8), 3058-64. Abstract

Zhou, J., Payen J. - F., Wilson D. A., Traystman R. J., & van Zijl P. C. M. (2003). Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI.. Nature medicine. 9(8), 1085-90. Abstract

Lu, H., Golay X., Pekar J. J., & van Zijl P. C. M. (2003). Functional magnetic resonance imaging based on changes in vascular space occupancy.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 50(2), 263-74. Abstract

Ronnett, G. V., Leopold D., Cai X., Hoffbuhr K. C., Moses L., Hoffman E. P., et al. (2003). Olfactory biopsies demonstrate a defect in neuronal development in Rett's syndrome.. Annals of neurology. 54(2), 206-18. Abstract

Stec, A. A. J., Wakim A., Barbet P., McCarthy E. F., Lakshmanan Y., Sponseller P. D., et al. (2003). Fetal bony pelvis in the bladder exstrophy complex: normal potential for growth?. Urology. 62(2), 337-41. Abstract

Iannone, R., Casella J. F., Fuchs E. J., Chen A. R., Jones R. J., Woolfrey A., et al. (2003). Results of minimally toxic nonmyeloablative transplantation in patients with sickle cell anemia and beta-thalassemia.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 9(8), 519-28. Abstract

Comi, A. M. (2003). Pathophysiology of Sturge-Weber syndrome.. Journal of child neurology. 18(8), 509-16. Abstract

Cooper, M. K., Wassif C. A., Krakowiak P. A., Taipale J., Gong R., Kelley R. I., et al. (2003). A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.. Nature genetics. 33(4), 508-13. Abstract

Matsui, W., Huff C. A., Vala M., Barber J., Smith D. B., & Jones R. J. (2003). Anti-tumour activity of interferon-alpha in multiple myeloma: role of interleukin 6 and tumor cell differentiation.. British journal of haematology. 121(2), 251-8. Abstract

Cohen, D. R. S., Matarazzo V., Palmer A. M., Tu Y., Jeon O. - H., Pevsner J., et al. (2003). Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis.. Molecular and cellular neurosciences. 22(4), 417-29. Abstract

Dorsi, M. J., Chen L., Meyer R. A., Pogatzki E., & Belzberg A. J. (2003). Ronald Tasker Award: a novel model of neuroma pain.. Clinical neurosurgery. 50, 382-6.

Heinzer, A. K., C McGuinness M., Lu J. - F., Stine C. O., Wei H., Van der Vlies M., et al. (2003). Mouse models and genetic modifiers in X-linked adrenoleukodystrophy.. Advances in experimental medicine and biology. 544, 75-93.

Moser, H. W., Raymond G. V., Koehler W., Sokolowski P., Hanefeld F., Korenke G. C., et al. (2003). Evaluation of the preventive effect of glyceryl trioleate-trierucate ("Lorenzo's oil") therapy in X-linked adrenoleukodystrophy: results of two concurrent trials.. Advances in experimental medicine and biology. 544, 369-87.

Cheng, L., Hammond H., Ye Z., Zhan X., & Dravid G. (2003). Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture.. Stem cells (Dayton, Ohio). 21(2), 131-42. Abstract

Johnston, M. V. (2003). Brain plasticity in paediatric neurology.. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. 7(3), 105-13. Abstract