Research Publications from 2002

Kennedy Krieger’s scientists and researchers are leaders in the worldwide effort to prevent and treat disorders of the brain, spinal cord, and musculoskeletal system. Learn about our innovative research initiatives and latest findings through our faculty research publications, Research Frontiers articles, and research press releases.

Slifer, K. J., Koontz K. L., & Cataldo M. F. (2002). Operant-contingency-based preparation of children for functional magnetic resonance imaging.. Journal of applied behavior analysis. 35(2), 191-4. Abstract

Sevin, B. M., Gulotta C. S., Sierp B. J., Rosica L. A., & Miller L. J. (2002). Analysis of response covariationamong multiple topographies of food refusal.. Journal of applied behavior analysis. 35(1), 65-8. Abstract

Nallamshetty, L., Ahn N. U., Ahn U. M., Buchowski J. M., An H. S., Rose P. S., et al. (2002). Plain radiography of the lumbosacral spine in Marfan syndrome.. The spine journal : official journal of the North American Spine Society. 2(5), 327-33. Abstract

Jones, K. B., Erkula G., Sponseller P. D., & Dormans J. P. (2002). Spine deformity correction in Marfan syndrome.. Spine. 27(18), 2003-12. Abstract

Frazier, J. L., Wang P. P., Patel S. H., Benson J. E., Cameron D. E., Hoon A. H., et al. (2002). Unusual migration of the distal catheter of a ventriculoperitoneal shunt into the heart: case report.. Neurosurgery. 51(3), 819-22; discussion 822. Abstract

Keysor, C. S., Mazzocco M. M. M., McLeod D. R., & Hoehn-Saric R. (2002). Physiological arousal in females with fragile X or Turner syndrome.. Developmental psychobiology. 41(2), 133-46. Abstract

Slomine, B. S., Gerring J. P., Grados M. A., Vasa R., Brady K. D., Christensen J. R., et al. (2002). Performance on measures of executive function following pediatric traumatic brain injury.. Brain injury : [BI]. 16(9), 759-72. Abstract

Caparrelli, D. J., Cattaneo S. M., Bethea B. T., Shake J. G., Eberhart C., Blue M. E., et al. (2002). Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia.. The Annals of thoracic surgery. 74(3), 838-44; discussion 844-5. Abstract

Cutting, L. E., Huang G. - H., Zeger S., Koth C. W., Thompson R. E., & Denckl M. B. (2002). Growth curve analyses of neuropsychological profiles in children with neurofibromatosis type 1: specific cognitive tests remain "spared" and "impaired" over time.. Journal of the International Neuropsychological Society : JINS. 8(6), 838-46. Abstract

Mostofsky, S. H., Cooper K. L., Kates W. R., Denckla M. B., & Kaufmann W. E. (2002). Smaller prefrontal and premotor volumes in boys with attention-deficit/hyperactivity disorder.. Biological psychiatry. 52(8), 785-94. Abstract

Zabel, A. T., & Chute D. L. (2002). Educational neuroimaging: a proposed neuropsychological application of near-infrared spectroscopy (nIRS).. The Journal of head trauma rehabilitation. 17(5), 477-88. Abstract

Mahone, M. E., Cirino P. T., Cutting L. E., Cerrone P. M., Hagelthorn K. M., Hiemenz J. R., et al. (2002). Validity of the behavior rating inventory of executive function in children with ADHD and/or Tourette syndrome.. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. 17(7), 643-62. Abstract

Yantis, S., Schwarzbach J., Serences J. T., Carlson R. L., Steinmetz M. A., Pekar J. J., et al. (2002). Transient neural activity in human parietal cortex during spatial attention shifts.. Nature neuroscience. 5(10), 995-1002. Abstract

Eichler, F. S., Itoh R., Barker P. B., Mori S., Garrett E. S., van Zijl P. C. M., et al. (2002). Proton MR spectroscopic and diffusion tensor brain MR imaging in X-linked adrenoleukodystrophy: initial experience.. Radiology. 225(1), 245-52. Abstract

Lu, H., Golay X., & van Zijl P. C. M. (2002). Intervoxel heterogeneity of event-related functional magnetic resonance imaging responses as a function of T(1) weighting.. NeuroImage. 17(2), 943-55. Abstract

Nishimura, A., Hohmann C. F., Johnston M. V., & Blue M. E. (2002). Neonatal electrolytic lesions of the basal forebrain stunt plasticity in mouse barrel field cortex.. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 20(6), 481-9. Abstract

Slifer, K. J., Eischen S. E., & Busby S. (2002). Using counterconditioning to treat behavioural distress during subcutaneous injections in a paediatric rehabilitation patient.. Brain injury : [BI]. 16(10), 901-16. Abstract

Cummings, D. D., Singer H. S., Krieger M., Miller T. L., & Mahone M. E. (2002). Neuropsychiatric effects of guanfacine in children with mild tourette syndrome: a pilot study.. Clinical neuropharmacology. 25(6), 325-32. Abstract

Kaczorowski, D. J., Patterson E. S., Jastromb W. E., & Shamblott M. J. (2002). Glucose-responsive insulin-producing cells from stem cells.. Diabetes/metabolism research and reviews. 18(6), 442-50. Abstract

Mori, S., & van Zijl P. C. M. (2002). Fiber tracking: principles and strategies - a technical review.. NMR in biomedicine. 15(7-8), 468-80. Abstract

Jones, K. B., Sponseller P. D., Hobbs W., & Pyeritz R. E. (2002). Leg-length discrepancy and scoliosis in Marfan syndrome.. Journal of pediatric orthopedics. 22(6), 807-12. Abstract

Kates, W. R., Frederikse M., Mostofsky S. H., Folley B. S., Cooper K., Mazur-Hopkins P., et al. (2002). MRI parcellation of the frontal lobe in boys with attention deficit hyperactivity disorder or Tourette syndrome.. Psychiatry research. 116(1-2), 63-81. Abstract

Kelley, R. I., Robinson D., Puffenberger E. G., Strauss K. A., & Morton H. D. (2002). Amish lethal microcephaly: a new metabolic disorder with severe congenital microcephaly and 2-ketoglutaric aciduria.. American journal of medical genetics. 112(4), 318-26. Abstract

Xu, D., Mori S., Solaiyappan M., van Zijl P. C. M., & Davatzikos C. (2002). A framework for callosal fiber distribution analysis.. NeuroImage. 17(3), 1131-43. Abstract

Moran, T. H., Capone G. T., Knipp S., Davisson M. T., Reeves R. H., & Gearhart J. D. (2002). The effects of piracetam on cognitive performance in a mouse model of Down's syndrome.. Physiology & behavior. 77(2-3), 403-9. Abstract

Colantuoni, C., Henry G., Zeger S., & Pevsner J. (2002). SNOMAD (Standardization and NOrmalization of MicroArray Data): web-accessible gene expression data analysis.. Bioinformatics (Oxford, England). 18(11), 1540-1. Abstract

Kaufmann, W. E., Cohen S., Sun H. - T., & Ho G. (2002). Molecular phenotype of Fragile X syndrome: FMRP, FXRPs, and protein targets.. Microscopy research and technique. 57(3), 135-44. Abstract

Kates, W. R., Folley B. S., Lanham D. C., Capone G. T., & Kaufmann W. E. (2002). Cerebral growth in Fragile X syndrome: review and comparison with Down syndrome.. Microscopy research and technique. 57(3), 159-67. Abstract

Kau, A. S. M., Meyer W. A., & Kaufmann W. E. (2002). Early development in males with Fragile X syndrome: a review of the literature.. Microscopy research and technique. 57(3), 174-8. Abstract

Keysor, C. S., & Mazzocco M. M. M. (2002). A developmental approach to understanding Fragile X syndrome in females.. Microscopy research and technique. 57(3), 179-86. Abstract

Golay, X., Jiang H., van Zijl P. C. M., & Mori S. (2002). High-resolution isotropic 3D diffusion tensor imaging of the human brain.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 47(5), 837-43. Abstract

Leet, A. I., Frisancho J., & Ebramzadeh E. (2002). Delayed treatment of type 3 supracondylar humerus fractures in children.. Journal of pediatric orthopedics. 22(2), 203-7. Abstract

Mori, S., Frederiksen K., van Zijl P. C. M., Stieltjes B., Kraut M. A., Solaiyappan M., et al. (2002). Brain white matter anatomy of tumor patients evaluated with diffusion tensor imaging.. Annals of neurology. 51(3), 377-80. Abstract

Ali, Z., Meyer R. A., & Belzberg A. J. (2002). Neuropathic pain after C7 spinal nerve transection in man.. Pain. 96(1-2), 41-7. Abstract

Mahone, M. E., Hagelthorn K. M., Cutting L. E., Schuerholz L. J., Pelletier S. F., Rawlins C., et al. (2002). Effects of IQ on executive function measures in children with ADHD.. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. 8(1), 52-65. Abstract

Sheth, R. N., Dorsi M. J., Li Y., Murinson B. B., Belzberg A. J., Griffin J. W., et al. (2002). Mechanical hyperalgesia after an L5 ventral rhizotomy or an L5 ganglionectomy in the rat.. Pain. 96(1-2), 63-72. Abstract

Lipkin, P. H., Davidson D., Spivak L., Straube R., Rhines J., & Chang C. T. (2002). Neurodevelopmental and medical outcomes of persistent pulmonary hypertension in term newborns treated with nitric oxide.. The Journal of pediatrics. 140(3), 306-10. Abstract

Huff, C. A., & Jones R. J. (2002). Bone marrow transplantation for multiple myeloma: where we are today.. Current opinion in oncology. 14(2), 147-51. Abstract

Kelley, R. I., Kratz L. E., Glaser R. L., Netzloff M. L., Wolf L. M., & Jabs E. W. (2002). Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia.. American journal of medical genetics. 110(2), 95-102. Abstract

Shindle, M. K., Khanna J. A., McCarthy E. F., O'Neill P. J., & Sponseller P. D. (2002). Desmoid tumor of the spinal canal causing scoliosis and paralysis.. Spine. 27(12), E304-7. Abstract

Schlund, M. W. (2002). Effects of acquired brain injury on adaptive choice and the role of reduced sensitivity to contingencies.. Brain injury : [BI]. 16(6), 527-35. Abstract

Albayram, S., Melhem E. R., Mori S., Zinreich J. S., Barkovich J. A., & Kinsman S. L. (2002). Holoprosencephaly in children: diffusion tensor MR imaging of white matter tracts of the brainstem--initial experience.. Radiology. 223(3), 645-51. Abstract

Gusenoff, J. A., Redett R. J., & Nahabedian M. Y. (2002). Outcomes for surgical coverage of pressure sores in nonambulatory, nonparaplegic, elderly patients.. Annals of plastic surgery. 48(6), 633-40. Abstract

Smith, D. B., Jones R. J., Lee S. M., Piantadosi S., Vala M. S., Fuller D., et al. (2002). Autologous bone marrow transplantation with 4-hydroperoxycyclophosphamide purging for acute myeloid leukaemia beyond first remission: a 10-year experience.. British journal of haematology. 117(4), 907-13. Abstract

Colantuoni, C., Henry G., Zeger S., & Pevsner J. (2002). Local mean normalization of microarray element signal intensities across an array surface: quality control and correction of spatially systematic artifacts.. BioTechniques. 32(6), 1316-20. Abstract

Matsui, W. H., Gladstone D. E., Vala M. S., Barber J. P., Brodsky R. A., Smith D. B., et al. (2002). The role of growth factors in the activity of pharmacological differentiation agents.. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. 13(6), 275-83. Abstract

Domb, B. G., Sponseller P. D., Ain M., & Miller N. H. (2002). Comparison of dynamic versus static external fixation for pediatric femur fractures.. Journal of pediatric orthopedics. 22(4), 428-30. Abstract

Mihalik, S. J., Steinberg S. J., Pei Z., Park J., Kim D. G., Heinzer A. K., et al. (2002). Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling.. The Journal of biological chemistry. 277(27), 24771-9. Abstract

Bannon, D. I., Portnoy M. E., Olivi L., Lees P. S. J., Culotta V. C., & Bressler J. P. (2002). Uptake of lead and iron by divalent metal transporter 1 in yeast and mammalian cells.. Biochemical and biophysical research communications. 295(4), 978-84. Abstract

Moyo, V. M., Smith D., Brodsky I., Crilley P., Jones R. J., & Brodsky R. A. (2002). High-dose cyclophosphamide for refractory autoimmune hemolytic anemia.. Blood. 100(2), 704-6. Abstract

Goh, D. L. M., Patel A., Thomas G. H., Salomons G. S., Schor D. S. M., Jakobs C., et al. (2002). Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT).. Molecular genetics and metabolism. 76(3), 172-80. Abstract

McCarthy, M. L., Silberstein C. E., Atkins E. A., Harryman S. E., Sponseller P. D., & Hadley-Miller N. A. (2002). Comparing reliability and validity of pediatric instruments for measuring health and well-being of children with spastic cerebral palsy.. Developmental medicine and child neurology. 44(7), 468-76. Abstract

Calhoun, V. D., Pekar J. J., McGinty V. B., Adali T., Watson T. D., & Pearlson G. D. (2002). Different activation dynamics in multiple neural systems during simulated driving.. Human brain mapping. 16(3), 158-67. Abstract

Jones, K. B., Sponseller P. D., & Gearhart J. P. (2002). Staged closure of the pelvis in secondary repair of cloacal exstrophy in the older patient.. Journal of pediatric orthopedics. 22(1), 67-72. Abstract

Tortolani, J. P., McCarthy E. F., & Sponseller P. D. (2002). Bone mineral density deficiency in children.. The Journal of the American Academy of Orthopaedic Surgeons. 10(1), 57-66. Abstract

Abounader, R., Lal B., Luddy C., Koe G., Davidson B., Rosen E. M., et al. (2002). In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 16(1), 108-10. Abstract

Melhem, E. R., Mori S., Mukundan G., Kraut M. A., Pomper M. G., & van Zijl P. C. M. (2002). Diffusion tensor MR imaging of the brain and white matter tractography.. AJR. American journal of roentgenology. 178(1), 3-16.

Pidcock, F. S., Wise J. M., & Christensen J. R. (2002). Treatment of severe post-traumatic bruxism with botulinum toxin-A: case report.. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 60(1), 115-7.

Speedie, L. J., Wertman E., Verfaellie M., Butter C., Silberman N., Liechtenstein M., et al. (2002). Reading direction and spatial neglect.. Cortex; a journal devoted to the study of the nervous system and behavior. 38(1), 59-67. Abstract

Mori, S., Kaufmann W. E., Davatzikos C., Stieltjes B., Amodei L., Fredericksen K., et al. (2002). Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 47(2), 215-23. Abstract

Golay, X., Gillen J., van Zijl P. C. M., & Barker P. B. (2002). Scan time reduction in proton magnetic resonance spectroscopic imaging of the human brain.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 47(2), 384-7. Abstract

Hwang, K. - Y., Lee B. - K., Bressler J. P., Bolla K. I., Stewart W. F., & Schwartz B. S. (2002). Protein kinase C activity and the relations between blood lead and neurobehavioral function in lead workers.. Environmental health perspectives. 110(2), 133-8. Abstract

Horská, A., Kaufmann W. E., Brant L. J., Naidu S., Harris J. C., & Barker P. B. (2002). In vivo quantitative proton MRSI study of brain development from childhood to adolescence.. Journal of magnetic resonance imaging : JMRI. 15(2), 137-43. Abstract

Vasa, R. A., Gerring J. P., Grados M., Slomine B., Christensen J. R., Rising W., et al. (2002). Anxiety after severe pediatric closed head injury.. Journal of the American Academy of Child and Adolescent Psychiatry. 41(2), 148-56. Abstract

Gerring, J. P., Slomine B., Vasa R. A., Grados M., Chen A., Rising W., et al. (2002). Clinical predictors of posttraumatic stress disorder after closed head injury in children.. Journal of the American Academy of Child and Adolescent Psychiatry. 41(2), 157-65. Abstract

Bouton, C. M. L. S., & Pevsner J. (2002). DRAGON View: information visualization for annotated microarray data.. Bioinformatics (Oxford, England). 18(2), 323-4. Abstract

Bastian, A. J. (2002). Cerebellar limb ataxia: abnormal control of self-generated and external forces.. Annals of the New York Academy of Sciences. 978, 16-27. Abstract

Mahone, M. E., Zabel A. T., Levey E., Verda M., & Kinsman S. (2002). Parent and self-report ratings of executive function in adolescents with myelomeningocele and hydrocephalus.. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. 8(4), 258-70. Abstract

Denckla, M. B. (2002). The Behavior Rating Inventory of Executive Function: commentary.. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence. 8(4), 304-6.

South, M., Williams B. J., McMahon W. M., Owley T., Filipek P. A., Shernoff E., et al. (2002). Utility of the Gilliam Autism Rating Scale in research and clinical populations.. Journal of autism and developmental disorders. 32(6), 593-9. Abstract

Li, X., Baumgart E., Dong G. - X., Morrell J. C., Jimenez-Sanchez G., Valle D., et al. (2002). PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation.. Molecular and cellular biology. 22(23), 8226-40. Abstract

Shindle, M. K., Khanna J. A., Hoehner J. C., O'Neill P. J., & Sponseller P. D. (2002). Colonic perforation complicating posteroanterior fusion using fibular strut autograft for a high-grade spondylolisthesis.. Journal of spinal disorders & techniques. 15(6), 546-9. Abstract

Heinzer, A. K., Kemp S., Lu J. - F., Watkins P. A., & Smith K. D. (2002). Mouse very long-chain acyl-CoA synthetase in X-linked adrenoleukodystrophy.. The Journal of biological chemistry. 277(32), 28765-73. Abstract

Onyango, P., Jiang S., Uejima H., Shamblott M. J., Gearhart J. D., Cui H., et al. (2002). Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages.. Proceedings of the National Academy of Sciences of the United States of America. 99(16), 10599-604. Abstract

Brushart, T. M., Hoffman P. N., Royall R. M., Murinson B. B., Witzel C., & Gordon T. (2002). Electrical stimulation promotes motoneuron regeneration without increasing its speed or conditioning the neuron.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22(15), 6631-8. Abstract

Nallamshetty, L., Ahn N. U., Ahn U. M., Nallamshetty H. S., Rose P. S., Buchowski J. M., et al. (2002). Dural ectasia and back pain: review of the literature and case report.. Journal of spinal disorders & techniques. 15(4), 326-9. Abstract

Villemagne, P. M., Naidu S., Villemagne V. L., Yaster M., Wagner H. N., Harris J. C., et al. (2002). Brain glucose metabolism in Rett Syndrome.. Pediatric neurology. 27(2), 117-22. Abstract

Conant, K., Haughey N., Nath A., St Hillaire C., Gary D. S., Pardo C. A., et al. (2002). Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9.. Journal of neurochemistry. 82(4), 885-93. Abstract

Tagawa, Y., Laroy W., Nimrichter L., Fromholt S. E., Moser A. B., Moser H. W., et al. (2002). Anti-ganglioside antibodies bind with enhanced affinity to gangliosides containing very long chain fatty acids.. Neurochemical research. 27(7-8), 847-55. Abstract

Erkula, G., Jones K. B., Sponseller P. D., Dietz H. C., & Pyeritz R. E. (2002). Growth and maturation in Marfan syndrome.. American journal of medical genetics. 109(2), 100-15. Abstract

Cargile, C. B., Goh D. L. - M., Goodman B. K., Chen X. - N., Korenberg J. R., Semenza G. L., et al. (2002). Molecular cytogenetic characterization of a subtle interstitial del(3)(p25.3p26.2) in a patient with deletion 3p syndrome.. American journal of medical genetics. 109(2), 133-8. Abstract

Sung, Y. K., Moon C., Yoo J. - Y., Moon C., Pearse D., Pevsner J., et al. (2002). Plunc, a member of the secretory gland protein family, is up-regulated in nasal respiratory epithelium after olfactory bulbectomy.. The Journal of biological chemistry. 277(15), 12762-9. Abstract

Zhang, J., van Zijl P. C. M., & Mori S. (2002). Three-dimensional diffusion tensor magnetic resonance microimaging of adult mouse brain and hippocampus.. NeuroImage. 15(4), 892-901. Abstract

Walter, K. A., Hossain M. A., Luddy C., Goel N., Reznik T. E., & Laterra J. (2002). Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription.. Molecular and cellular biology. 22(8), 2703-15. Abstract

Goto, S., Xue R., Sugo N., Sawada M., Blizzard K. K., Poitras M. F., et al. (2002). Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery.. Stroke; a journal of cerebral circulation. 33(4), 1101-6. Abstract

Jiang, H., Golay X., van Zijl P. C. M., & Mori S. (2002). Origin and minimization of residual motion-related artifacts in navigator-corrected segmented diffusion-weighted EPI of the human brain.. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 47(4), 818-22. Abstract

Schlund, M. W. (2002). The effects of brain injury on choice and sensitivity to remote consequences: deficits in discriminating response-consequence relations.. Brain injury : [BI]. 16(4), 347-57. Abstract

Pevsner, J. (2002). Leonardo da Vinci's contributions to neuroscience.. Trends in neurosciences. 25(4), 217-20. Abstract

Hossain, M. A., Russell J. C., Gomez R., Laterra J., & Gomes R. (2002). Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/akt-dependent and MAPK/CREB-independent.. Journal of neurochemistry. 81(2), 365-78. Abstract

Poole, L. J., Yu Y., Kim P. S., Zheng Q. - Z., Pevsner J., & Hayward G. S. (2002). Altered patterns of cellular gene expression in dermal microvascular endothelial cells infected with Kaposi's sarcoma-associated herpesvirus.. Journal of virology. 76(7), 3395-420. Abstract

Andreasson, K. I., & Kaufmann W. E. (2002). Role of immediate early gene expression in cortical morphogenesis and plasticity.. Results and problems in cell differentiation. 39, 113-37. Abstract

Nestadt, G., Samuels J. F., Riddle M. A., Bienvenu J. O., Liang K. - Y., Grados M. A., et al. (2002). Obsessive-compulsive disorder: defining the phenotype.. The Journal of clinical psychiatry. 63 Suppl 6, 5-7. Abstract