A 20-week double blind placebo controlled clinical trial to evaluate the safety and efficacy of rivastigmine in children (ages 10-17) with Down syndrome

The specific aims of this study are to: a) investigate short-term safety and efficacy of rivastigmine treatment; b) build upon the open-label treatment results of overall function and language improvement in children with Down syndrome (DS) in a double-blind, placebo-controlled clinical trial; and c) investigate other specific cognitive domains that may selectively respond to rivastigmine treatment.

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