IDDRC Translational Neuroscience Core Supported Studies and Investigators

The Translational Neuroscience Core has historically supported approximately 30-40 studies annually. In recent years, the greatest demand has been for the M2-Apotome Microscope and Axiovision Image Analysis system, which is capable of providing investigators with confocal-like images. Currently, the Core supports the following studies and investigators.

Translational Neuroscience Core Studies and Investigators

 

P.I.

Grant Number and Title

 

Baumgartner

R01HL091541, Excitotoxicity in circulatory arrest-brain injury

Burd

K08HD073315, IL-1β regulation of perinatal brain injury

Calabresi

R01 NS041435, The role of KV1.3 in effector T cells

Calabresi

R21NS081418, Selective modulation of thyroid hormone receptors to promote remyelination

Comi

R01 NS061969, Anticonvulsants, ischemic seizures and regeneration in the immature brain

Culotta

R37 GM050016, Genetic determinants of oxygen toxicity

Fatemi

K08 NS063956, Study of White Matter Development in a Rodent Model of Perinatal Brain Injury

Hossain

R01 NS046030, Neurotrophin protection of hypoxic ischemic brain injury

Huganir

R01NS36715, PDZ domains and AMPA receptor function

Huganir

R01 MH095058, High throughput screen for small molecule probes for neural network development

Jonas

R01HL104173, Protection of developing white matter during cardiac surgery

Kannan

R01 HD069562, Mechanisms and novel therapy in intrauterine inflammation induced brain injury

Kazazian

R01GM099875, Retrotransposition in health and disease

Laterra

R01NS073611, Brain cancer stem cell reprogramming by c-Met

Laterra

R01NS076759, Suppression of Glioblastoma Stem Cells by Kruppel-Like Factor 9

Maegawa

R03MH098689, A novel cell-based assay to identify small molecules for B-Galactocerebroisidase

Marsh-Armstrong

RO1EY10157592, Optic Nerve Synucleinopathy in Glaucoma and the Function of gamma-Synuclein

Marsh-Armstrong

R01EY022680, Transcellular degardation of mitochondria in the central nervous system

Meffert

R01MH098016, Microma biogenesis and specificity in neurothrophin-dependent protein synthesis

Meffert

R01MH080740, Mechanisms and function of nf-kappab activation at dendritic spines

Naidu

R01FD004247, PH2 Study of Dextromethorpan in the Treatment of Rett Syndrome

Northington

R01HD070996, Mechanisms of hypothermic neuroprotection in neonates

Pelled

R01NS072171, The role of transcallosal pathway to neuroplasticity following nerve injury

Pelled/Gilad

R01NS079288, Adaptive control of epileptic seizures using a genetically encoded sensor

Reeves

R01HE038384, Genomic approaches in aneuploidy

Ronnett

RO1NS041079, Olfactory abnormalities in the modeling of Rett syndrome

Vernon

K08HD073492, Metabolic studies in disorders of branch chain amino acid metabolism

Wagner

U54 HD060848, Biomarkers for Therapy of FSHD

Wagner

R21NS079529, A novel xenograft mouse model of facioscapulohumeral muscular dystrophy

Zhou

R21 EB015555, Molecular MRI of radiation necrosis in preclinical models