IDDRC Genetics Core Supported Studies and Investigators

The Genetics Core historically supports approximately 20 – 30 studies annually. However, support has been expanding in recent years as ever more powerful methods have become available, and this trend is predicted to continue. The following list contains a summary of current studies supported by the Genetics Core.

Genetics Core Studies and Investigators

 

P.I.

Grant Number and Title

 

Avramopoulos

R01MH085018, Identification of genetic determinants of schizophrenia related phenotypes

Baumgartner

R01HL091541, Excitotoxicity in circulatory arrest-brain injury

Bondy

ZIAHD000628, Gender-specific effects in physiology, pathophysiology and longevity

Chakravarti

R37HD028088, Genetic analysis of Hirschsprung disease

Fallin/Newschaffer

R01ES016433 (NICHD co-funding), Early autism risk longitudinal investigation (EARLI) network

Fallin

R01ES017646 (NICHD co-funding), Environment, the perinatal epigenome, and risk for ASDs

Feinberg

P50 HG 003233, Center for the Epigenetics of Common Human Disease (CEGS)

Hagopian/Cataldo

P01HD055456, Translational Analyses of Chronic Aberrant Behavior across the Lifespan:  Project 3

Huganir

R01NS36715, PDZ domains and AMPA receptor function

Huganir

R01 MH095058, High throughput screen for small molecule probes for neural network development

Johnston/Gipson

K12NS001696, RAPT-Rapamycin for autism phenotype in tuberous sclerosis complex

Laterra

R01NS073611, Brain cancer stem cell reprogramming by c-Met

Laterra

R01NS076759, Suppression of Glioblastoma Stem Cells by Kruppel-Like Factor 9

Maegawa

R03MH098689, A novel cell-based assay to identify small molecules for B-Galactocerebroisidase

Bembea/Moler

U01HL094345, Therapeutic Hypothermia After Pediatric Cardiac Arrest: A Randomized Controlled Trial (THAPCA)

Naidu

R01FD004247, PH2 Study of Dextromethorpan in the treatment of Rett Syndrome

Reeves

R01HE038384, Genomic approaches in aneuploidy

Schupf/Silverman

P01HD035897, Aging and dementia in adults with Down syndrome:  Subproject 4

Silverman

P01HD035897, Aging and dementia in adults with Down syndrome

Tycko/Silverman

P01HD035897, Aging and dementia in adults with Down syndrome:  Subproject 3

Valle

U54HG006542, Baylor-Johns Hopkins Center for Mendelian Genetics

Vernon

K08HD073492, Metabolic studies in disorders of branch chain amino acid metabolism

Wang

R01 NS073854, Identification of Novel X-Linked Intellectual Disability Genes