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Variability in post-error behavioral adjustment is associated with functional abnormalities in the temporal cortex in children with ADHD.
|Title||Variability in post-error behavioral adjustment is associated with functional abnormalities in the temporal cortex in children with ADHD.|
|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Spinelli S, Vasa RA, Joel S, Nelson TE, Pekar JJ, Mostofsky SH|
|Journal||Journal of child psychology and psychiatry, and allied disciplines|
|Date Published||2011 Jul|
Error processing is reflected, behaviorally, by slower reaction times (RT) on trials immediately following an error (post-error). Children with attention-deficit hyperactivity disorder (ADHD) fail to show RT slowing and demonstrate increased intra-subject variability (ISV) on post-error trials. The neural correlates of these behavioral deficits remain unclear. The dorsal anterior cingulate cortex (ACC) and lateral prefrontal cortex (PFC) are key regions implicated in error processing and subsequent behavioral adjustment. We hypothesized that children with ADHD, compared to typically developing (TD) controls, would exhibit reduced PFC activation during post-error (versus post-correct inhibition) trials and reduced dACC activation during error (versus correct inhibition) trials.
|Alternate Journal||J Child Psychol Psychiatry|