Updated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica.

TitleUpdated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica.
Publication TypeJournal Article
Year of Publication2013
AuthorsJiao Y, Fryer JP, Lennon VA, Jenkins SM, Quek AML, Smith CY, McKeon A, Costanzi C, Iorio R, Weinshenker BG, Wingerchuk DM, Shuster EA, Lucchinetti CF, Pittock SJ
JournalNeurology
Volume81
Issue14
Pagination1197-204
Date Published2013 Oct 1
Abstract

To 1) determine, using contemporary recombinant antigen-based assays, the aquaporin-4 (AQP4)-immunoglobulin G (IgG) detection rate in sequential sera of patients assigned a clinical diagnosis of neuromyelitis optica (NMO) but initially scored negative by tissue-based indirect immunofluorescence (IIF) assay; and 2) evaluate the impact of serostatus on phenotype and outcome.

DOI10.1002/anie.201305010
Alternate JournalNeurology