Two New Highly Oxygenated and Rearranged Limonoids from Phyllanthus cochinchinensis.

TitleTwo New Highly Oxygenated and Rearranged Limonoids from Phyllanthus cochinchinensis.
Publication TypeJournal Article
Year of Publication2013
AuthorsZhao J-Q, Wang Y-M, He H-P, Li S-H, Li X-N, Yang C-R, Wang D, Zhu H-T, Xu M, Zhang Y-J
JournalOrganic letters
Date Published2013 May 2
Abstract

A new 6/6/5/6-fused limonoid, phyllanthoid A (1), possessing both 19/30 and 19/29 oxygen bridges was isolated from Phyllanthus cochinchinensis (Euphorbiaceae), together with a new related limonoid, phyllanthoid B (2). Their structures were determined by spectroscopic analysis and single-crystal X-ray diffraction in the case of 1. Compound 1 displayed moderate antifeedant against the generalist plant-feeding insect Spodoptera exigua and cytotoxicity against the MCF-7 cell line.

DOI10.1073/pnas.1301766110
Alternate JournalOrg. Lett.