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Two New Highly Oxygenated and Rearranged Limonoids from Phyllanthus cochinchinensis.
|Title||Two New Highly Oxygenated and Rearranged Limonoids from Phyllanthus cochinchinensis.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Zhao J-Q, Wang Y-M, He H-P, Li S-H, Li X-N, Yang C-R, Wang D, Zhu H-T, Xu M, Zhang Y-J|
|Date Published||2013 May 2|
A new 6/6/5/6-fused limonoid, phyllanthoid A (1), possessing both 19/30 and 19/29 oxygen bridges was isolated from Phyllanthus cochinchinensis (Euphorbiaceae), together with a new related limonoid, phyllanthoid B (2). Their structures were determined by spectroscopic analysis and single-crystal X-ray diffraction in the case of 1. Compound 1 displayed moderate antifeedant against the generalist plant-feeding insect Spodoptera exigua and cytotoxicity against the MCF-7 cell line.
|Alternate Journal||Org. Lett.|