A transition metal-free tandem process to pyridazinopyrido[3,2-f][1,4]thiazepine-diones via Smiles rearrangement.

TitleA transition metal-free tandem process to pyridazinopyrido[3,2-f][1,4]thiazepine-diones via Smiles rearrangement.
Publication TypeJournal Article
Year of Publication2013
AuthorsNiu X, Yang B, Li Y, Fang S, Huang Z, Xie C, Ma C
JournalOrganic & biomolecular chemistry
Volume11
Issue24
Pagination4102-8
Date Published2013 Jun 28
Abstract

A transition metal-free methodology for the synthesis of pyridazinopyrido[3,2-f][1,4]thiazepine-diones was studied. The construction of this tricyclic system went through a one-pot coupling/Smiles rearrangement/cyclization process. The high yields of pure products were obtained through simple recrystallization.

DOI10.3389/fonc.2013.00183
Alternate JournalOrg. Biomol. Chem.