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Targeting TGF-β signaling in cancer.
|Title||Targeting TGF-β signaling in cancer.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Katz LH, Li Y, Chen J-S, Muñoz NM, Majumdar A, Chen J, Mishra L|
|Journal||Expert opinion on therapeutic targets|
|Date Published||2013 Jul|
The transforming growth factor-β (TGF-β) signaling pathway has a pivotal role in tumor suppression and yet, paradoxically, in tumor promotion. Functional context dependent insights into the TGF-β pathway are crucial in developing TGF-β-based therapeutics for cancer.
|Alternate Journal||Expert Opin. Ther. Targets|