T-type Ca²⁺ channels regulate the exit of cardiac myocytes from the cell cycle after birth.

TitleT-type Ca²⁺ channels regulate the exit of cardiac myocytes from the cell cycle after birth.
Publication TypeJournal Article
Year of Publication2013
AuthorsWang F, Gao H, Kubo H, Fan X, Zhang H, Berretta R, Chen X, Sharp T, Starosta T, Makarewich C, Li Y, Molkentin JD, Houser SR
JournalJournal of molecular and cellular cardiology
Volume62
Pagination122-30
Date Published2013 Sep
Abstract

T-type Ca(2+) channels (TTCCs) are expressed in the fetal heart and then disappear from ventricular myocytes after birth. The hypothesis examined in this study was the α1G TTCCs' influence in myocyte maturation and their rapid withdrawal from the cell cycle after birth.

DOI10.1016/j.outlook.2013.03.006
Alternate JournalJ. Mol. Cell. Cardiol.