Synthesis of allyl allenes through three-component cross-coupling reaction of N-tosylhydrazones, terminal alkynes, and allyl halides.

TitleSynthesis of allyl allenes through three-component cross-coupling reaction of N-tosylhydrazones, terminal alkynes, and allyl halides.
Publication TypeJournal Article
Year of Publication2013
AuthorsYe F, Hossain ML, Xu Y, Ma X, Xiao Q, Zhang Y, Wang J
JournalChemistry, an Asian journal
Volume8
Issue7
Pagination1404-7
Date Published2013 Jul
Abstract

Three's a crowd: Tri- and tetrasubstituted allyl allenes can be easily accessed by this Cu(I)-catalyzed three-component coupling reaction of N-tosylhydrazones, terminal alkynes, and allyl halides. The reaction proceeds through a mechanism involving copper carbene migratory insertion.

DOI10.3978/j.issn.2072-1439.2013.08.53
Alternate JournalChem Asian J