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Striatum-based circuitry of adolescent depression and anhedonia.
|Title||Striatum-based circuitry of adolescent depression and anhedonia.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Gabbay V, Ely BA, Li Q, Bangaru SD, Panzer AM, Alonso CM, Castellanos XF, Milham MP|
|Journal||Journal of the American Academy of Child and Adolescent Psychiatry|
|Date Published||2013 Jun|
Striatum-based circuits have been implicated in both major depressive disorder (MDD) and anhedonia, a symptom that reflects deficits of reward processing. Yet adolescents with MDD often exhibit a wide range of anhedonia severity. Addressing this clinical phenomenon, we aimed to use intrinsic functional connectivity (iFC) to study striatum-based circuitry in relation to categorical diagnosis of MDD and anhedonia severity.
|Alternate Journal||J Am Acad Child Adolesc Psychiatry|