Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template.

TitleStereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template.
Publication TypeJournal Article
Year of Publication2008
AuthorsMori S, Oishi K, Jiang H, Jiang L, Li X, Akhter K, Hua K, Faria AV, Mahmood A, Woods R, Toga AW, Pike BG, Neto PR, Evans A, Zhang J, Huang H, Miller MI, van Zijl P, Mazziotta J
Date Published2008 Apr 1

Brain registration to a stereotaxic atlas is an effective way to report anatomic locations of interest and to perform anatomic quantification. However, existing stereotaxic atlases lack comprehensive coordinate information about white matter structures. In this paper, white matter-specific atlases in stereotaxic coordinates are introduced. As a reference template, the widely used ICBM-152 was used. The atlas contains fiber orientation maps and hand-segmented white matter parcellation maps based on diffusion tensor imaging (DTI). Registration accuracy by linear and non-linear transformation was measured, and automated template-based white matter parcellation was tested. The results showed a high correlation between the manual ROI-based and the automated approaches for normal adult populations. The atlases are freely available and believed to be a useful resource as a target template and for automated parcellation methods.

Alternate JournalNeuroimage