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Spinal cord quantitative MRI discriminates between disability levels in multiple sclerosis.
|Title||Spinal cord quantitative MRI discriminates between disability levels in multiple sclerosis.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Oh J, Saidha S, Chen M, Smith SA, Prince J, Jones C, Diener-West M, van Zijl PCM, Reich DS, Calabresi PA|
|Date Published||2013 Feb 5|
The clinicoradiologic paradox, or disconnect between clinical and radiologic findings, is frequently encountered in multiple sclerosis (MS), particularly in the spinal cord (SC), where lesions are expected to cause clinical impairment. We aimed to assess whether quantitative diffusion tensor and magnetization transfer imaging measures in the SC can distinguish MS cases of comparable lesion burdens with high and low disability.