News & Updates
Search Research Content
Resource Finder at Kennedy Krieger Institute
A free resource that provides access to information and support for individuals and families living with developmental disabilities.
Sipros/ProRata: a versatile informatics system for quantitative community proteomics.
|Title||Sipros/ProRata: a versatile informatics system for quantitative community proteomics.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Wang Y, Ahn T-H, Li Z, Pan C|
|Journal||Bioinformatics (Oxford, England)|
|Date Published||2013 Aug 15|
Sipros/ProRata is an open-source software package for end-to-end data analysis in a wide variety of community proteomics measurements. A database-searching program, Sipros 3.0, was developed for accurate general-purpose protein identification and broad-range post-translational modification searches. Hybrid Message Passing Interface/OpenMP parallelism of the new Sipros architecture allowed its computation to be scalable from desktops to supercomputers. The upgraded ProRata 3.0 performs label-free quantification and isobaric chemical labeling quantification in addition to metabolic labeling quantification. Sipros/ProRata is a versatile informatics system that enables identification and quantification of proteins and their variants in many types of community proteomics studies.