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Sex-Specific Associations Between Screen Time and Lipoprotein Subfractions.
|Title||Sex-Specific Associations Between Screen Time and Lipoprotein Subfractions.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Frazier-Wood AC, Borecki IB, Feitosa MF, Hopkins PN, Smith CE, Arnett DK|
|Journal||International journal of sport nutrition and exercise metabolism|
|Date Published||2013 Aug 26|
Background: Time spent in sedentary activities (such as watching television) has previously been associated with several risk factors for cardiovascular disease (CVD) such as increased low-density lipoprotein cholesterol (LDL-C). Little is known about associations with lipoprotein subfractions. Using television and computer screen time in hours per day as a measure of sedentary time, we examined the association of screen time with lipoprotein subfractions. Methods: Data were used from men and women forming the Genetics of Lipid Lowering Drugs Network (GOLDN) study population. Mixed linear models specified lipoprotein measures as the outcome, and screen time as the predictor for fourteen lipoprotein subfraction measures, and included age, smoking status, pedigree, and fat, carbohydrate daily alcohol and energy intake as covariates. Analyses were run separately for men (N=623) and women (N=671). A step-down Bonferroni correction was applied to results. The analysis was repeated for significant results (P<.05), additionally controlling for body mass index (BMI) and moderate and vigorous physical activity. Results: Linear models indicated that screen time was associated with five lipoprotein parameters in women: the concentration of large VLDL particles (P=.01), LDL particle number (P=.01), concentration of small LDL particles (P=.04), the concentration of large HDL particles (P=.04), and HDL diameter (P=.02). All associations remained after controlling for moderate or vigorous physical activity and BMI. Conclusions: We show that sedentary time is associated with lipoprotein measures, markers of cardiometabolic disease, independently of physical activity and BMI, in women but not men.
|Alternate Journal||Int J Sport Nutr Exerc Metab|