Selective reduction of amides to amines by boronic acid catalyzed hydrosilylation.

TitleSelective reduction of amides to amines by boronic acid catalyzed hydrosilylation.
Publication TypeJournal Article
Year of Publication2013
AuthorsLi Y, Molina de La Torre JA, Grabow K, Bentrup U, Junge K, Zhou S, Brückner A, Beller M
JournalAngewandte Chemie (International ed. in English)
Volume52
Issue44
Pagination11577-80
Date Published2013 Oct 25
Abstract

Not a 'B'ore! Benzothiophene-based boronic acids catalyze the reduction of tertiary, secondary, and primary amides in the presence of a hydrosilane. The reaction demonstrates good functional-group tolerance.

DOI10.1080/17441730.2013.807597
Alternate JournalAngew. Chem. Int. Ed. Engl.