The role of centralized reading of endoscopy in a randomized controlled trial of mesalamine for ulcerative colitis.

TitleThe role of centralized reading of endoscopy in a randomized controlled trial of mesalamine for ulcerative colitis.
Publication TypeJournal Article
Year of Publication2013
AuthorsFeagan BG, Sandborn WJ, D'Haens G, Pola S, McDonald JW, Rutgeerts P, Munkholm P, Mittmann U, King D, Wong CJ, Zou G, Donner A, Shackelton LM, Gilgen D, Nelson S, Vandervoort MK, Fahmy M, Loftus EV, Panaccione R, Travis SP, Van Assche GA, Vermeire S, Levesque BG
JournalGastroenterology
Volume145
Issue1
Pagination149-157.e2
Date Published2013 Jul
Abstract

Interobserver differences in endoscopic assessments contribute to variations in rates of response to placebo in ulcerative colitis (UC) trials. We investigated whether centralized review of images could reduce these variations.

DOI10.1371/journal.pone.0077060
Alternate JournalGastroenterology