Reduced insulin sensitivity in adults with pseudohypoparathyroidism type 1a.

TitleReduced insulin sensitivity in adults with pseudohypoparathyroidism type 1a.
Publication TypeJournal Article
Year of Publication2013
AuthorsMuniyappa R, Warren MA, Zhao X, Aney SC, Courville AB, Chen KY, Brychta RJ, Germain-Lee EL, Weinstein LS, Skarulis MC
JournalThe Journal of clinical endocrinology and metabolism
Volume98
Issue11
PaginationE1796-801
Date Published2013 Nov
Abstract

Disruption of the Gsα maternal allele leads to severe obesity and insulin resistance in mice and early-onset obesity in patients with pseudohypoparathyroidism (PHP) type 1a. However, insulin resistance and glucose metabolism have not been systematically characterized in patients with PHP1a.

DOI10.7717/peerj.132
Alternate JournalJ. Clin. Endocrinol. Metab.