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Reduced Graphene Oxide Functionalized with a Luminescent Rare-Earth Complex for the Tracking and Photothermal Killing of Drug-Resistant Bacteria.
|Title||Reduced Graphene Oxide Functionalized with a Luminescent Rare-Earth Complex for the Tracking and Photothermal Killing of Drug-Resistant Bacteria.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Yang X, Li Z, Ju E, Ren J, Qu X|
|Journal||Chemistry (Weinheim an der Bergstrasse, Germany)|
|Date Published||2013 Dec 10|
An antibacterial platform based on multifunctional reduced graphene oxide (rGO) that is responsive to near-infrared (NIR) light has been constructed. By introducing a luminescent Eu(3+) complex and vancomoycin for bacteria tracking into one system, this platform could specifically recognize and light up bacteria. Antibacterial activity of this nanoscale construction under NIR illumination was investigated. Upon illumination with NIR light, this nanoscale architecture generates great heat locally, resulting in the death of drug-resistant bacteria. These results indicate that the ability of this nanoscale platform to kill drug-resistant bacteria has great potential for clinical pathogenic bacteria diagnosis and treatment.