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Quantitative analysis of polysorbates 20 and 40 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
|Title||Quantitative analysis of polysorbates 20 and 40 by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Zhang Q, Meng Y, Yang H, Xiao X, Li X|
|Journal||Rapid communications in mass spectrometry : RCM|
|Date Published||2013 Dec 30|
Polysorbates are nonionic surfactants that consist primarily of fatty acid esters of polyethoxy sorbitan. This study proved that polysorbates can be quantitatively analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Using MALDI-TOF MS, relative intensity and concentration ratios were correlated, and extensive research was conducted to understand the influencing factors.
|Alternate Journal||Rapid Commun. Mass Spectrom.|