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Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids.
|Title||Prospective observational single-centre cohort study to evaluate the effectiveness of treating lupus nephritis with rituximab and mycophenolate mofetil but no oral steroids.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Condon MB, Ashby D, Pepper RJ, Cook TH, Levy JB, Griffith M, Cairns TD, Lightstone L|
|Journal||Annals of the rheumatic diseases|
|Date Published||2013 Aug|
Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE). All current treatment regimens include oral steroids, which are associated with severe adverse events and long-term damage. We have piloted a steroid-avoiding protocol (rituxilup) for the treatment of biopsy-proven active International Society of Nephrology/Renal Pathology Society (ISN/RPS) class III, IV, or class V LN.
|Alternate Journal||Ann. Rheum. Dis.|