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Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology.
| Title | Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology. |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Abazyan B, Nomura J, Kannan G, Ishizuka K, Tamashiro KL, Nucifora F, Pogorelov V, Ladenheim B, Yang C, Krasnova IN, Cadet JL, Pardo C, Mori S, Kamiya A, Vogel MW, Sawa A, Ross CA, Pletnikov MV |
| Journal | Biological psychiatry |
| Volume | 68 |
| Issue | 12 |
| Pagination | 1172-81 |
| Date Published | 2010 Dec 15 |
| Abstract | Gene-environment interactions (GEI) are involved in the pathogenesis of mental diseases. We evaluated interaction between mutant human disrupted-in-schizophrenia 1 (mhDISC1) and maternal immune activation implicated in schizophrenia and mood disorders. |
| DOI | 10.1097/CCM.0b013e31825457b8 |
| Alternate Journal | Biol. Psychiatry |
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