[Preliminary study of MALDI-TOF mass spectrometry-based screening of patients with the NSCLC serum-specific peptides].

Title[Preliminary study of MALDI-TOF mass spectrometry-based screening of patients with the NSCLC serum-specific peptides].
Publication TypeJournal Article
Year of Publication2013
AuthorsAn J, Tang C, Wang N, Liu Y, Guo W, Li X, Wang Z, He K, Liu X
JournalZhongguo fei ai za zhi = Chinese journal of lung cancer
Volume16
Issue5
Pagination233-9
Date Published2013 May
Abstract

The improved survival of patients with lung cancer depends on early diagnosis of lung cancer. However, the traditional diagnostic techniques have several limitations. Mass spectrometry (MS) has been applied as a core technology for cancer diagnosis in preliminary proteomic studies. The aim of this study is to explore the differences in the serum peptide levels of patients with non-small cell lung cancer (NSCLC) and healthy individuals using matrix-assisted laser desorption/ionization (MALDI)-time-of-flight (TOF)-MS. A NSCLC serum classification model was then established.

DOI10.5603/CJ.a2013.0057
Alternate JournalZhongguo Fei Ai Za Zhi