Polymorphisms but not mutations of the KCNQ1 gene are associated with lone atrial fibrillation in the Chinese Han population.

TitlePolymorphisms but not mutations of the KCNQ1 gene are associated with lone atrial fibrillation in the Chinese Han population.
Publication TypeJournal Article
Year of Publication2013
AuthorsChu H-M, Feng M-J, Li Y-G, Zhang Y-X, Ma J-F, He B, Yu Y-B, Liu J, Chen X-M
JournalTheScientificWorldJournal
Volume2013
Pagination373454
Date Published2013
Abstract

Recent studies suggest that mutation of the slow delayed rectifier potassium channel (IKs) contributes to familial atrial fibrillation (FAF). In the current study, we identified common genetic variants of KCNQ1 and explored the potential association between KCNQ1 polymorphism with lone AF (LAF).

DOI10.1084/jem.20130212
Alternate JournalScientificWorldJournal