Polymorphisms in metabolism/antioxidant genes may mediate the effect of dietary intake on pancreatic cancer risk.

TitlePolymorphisms in metabolism/antioxidant genes may mediate the effect of dietary intake on pancreatic cancer risk.
Publication TypeJournal Article
Year of Publication2013
AuthorsJansen RJ, Robinson DP, Stolzenberg-Solomon RZ, Bamlet WR, Tan X, Cunningham JM, Li Y, Rider DN, Oberg AL, Rabe KG, Anderson KE, Sinha R, Petersen GM
JournalPancreas
Volume42
Issue7
Pagination1043-53
Date Published2013 Oct
Abstract

A source of variation for inconsistent dietary-pancreatic cancer associations may be individuals carrying constitutional metabolism/antioxidant gene variants that differentially benefit compared to homozygous individuals. Seventy-six tag single-nucleotide polymorphisms were genotyped in 13 candidate genes to test differential associations with pancreatic adenocarcinoma.

DOI10.1007/s11033-013-2762-5
Alternate JournalPancreas